[PDF] Top 20 Study of the Transcription and the Replication of Vesicular Stomatitis Virus by Using Temperature-Sensitive Mutants
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Study of the Transcription and the Replication of Vesicular Stomatitis Virus by Using Temperature-Sensitive Mutants
... Study of the Transcription and the Replication of Vesicular Stomatitis Virus by Using Temperature-Sensitive Mutants Received for publication 6 September 1972 The viral ribonucleic acids [r] ... See full document
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Temperature-sensitive mutants of vesicular stomatitis virus are conditionally defective particles that interfere with and are rescued by wild-type virus.
... QUAGLIANA Department of Microbiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 Received for publication 11 March 1976 In 1973 Preble and Youngner repo[r] ... See full document
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Temperature-Sensitive Mutants of Complementation Group E of Vesicular Stomatitis Virus New Jersey Serotype Possess Altered NS Polypeptides
... The NS polypeptides of all three mutants were labeled with 'Pi to approximately the same extent as wildtype virus NS polypeptide, indicating that gross differences in phosphorylation of [r] ... See full document
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Envelope proteins and replication of vesicular stomatitis virus: in vivo effects of RNA+ temperature-sensitive mutations on viral RNA synthesis.
... 1 Envelope Proteins and Replication of Vesicular Stomatitis Virus: In Vivo Effects of RNA' Temperature-Sensitive Mutations on Viral RNA Synthesis CLAIRE MARTINET,* ARLETTE COMBARD, CHRIS[r] ... See full document
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Differential inhibition of host protein synthesis in L cells infected with RNA - temperature-sensitive mutants of vesicular stomatitis virus.
... Since virus-specific polypeptides are readily identified, the comparative inhibition of host cell protein synthesis and accumulation of virus-specific proteins were determined by differe[r] ... See full document
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Neuropeptide-induced hypothermia and the course of central nervous system disease mediated by temperature-sensitive mutants of vesicular stomatitis virus.
... The course of disease in mice produced by infection with another temperature-sensitive VSV mutant, tsGll VSV complementation group I, also was altered when neurotensin was injected befor[r] ... See full document
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Overlapping Signals for Transcription and Replication at the 3′ Terminus of the Vesicular Stomatitis Virus Genome
... of transcription from these mutant tem- plates by examining the 59 termini of the NDL mRNAs pro- duced from the mutant ...mRNA transcription product and generates the extension products (the doublet marked ... See full document
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Primary In Vivo Transcription of Vesicular Stomatitis Virus and Temperature-Sensitive Mutants of Five Vesicular Stomatitis Virus Complementation Groups
... Primary In Vivo Transcription of Vesicular Stomatitis Virus and Temperature-Sensitive Mutants of Five Vesicular Stomatitis Virus Complementation Groups Received for publication 16 July 1[r] ... See full document
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Phenotypic revertants of temperature-sensitive M protein mutants of vesicular stomatitis virus: sequence analysis and functional characterization.
... 256 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Twenty-five spontaneous temperature-stable revertants of four different temperature-sensitive ts M protein mutants c[r] ... See full document
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Temperature-Sensitive Mutants of Vesicular Stomatitis Virus: Comparison of the In Vitro RNA Polymerase Defects of Group I and Group IV Mutants
... The fact that revertants of mutants tsW15 and tsW28 that had regained their ability to replicate and form infectious virus at 38 C had also reverted to a wild-type transcriptase beDISCUS[r] ... See full document
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Analysis of the defects of temperature-sensitive mutants of vesicular stomatitis virus: intracellular degradation of specific viral proteins.
... Certain viral proteins encoded by the mutant strains, usually the putative mutant protein for the assigned complementation group, were shown to be degraded more rapidly at the nonpermiss[r] ... See full document
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Sequence alterations in temperature-sensitive M-protein mutants (complementation group III) of vesicular stomatitis virus.
... DISCUSSION In comparing the sequences for wild-type M protein of three different strains-the two in this paper and the one of Rose and Gallione 19-it is noteworthy that of the eight amin[r] ... See full document
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RNA- temperature-sensitive mutants of vesicular stomatitis virus: L-protein thermosensitivity accounts for transcriptase restriction of group I mutants.
... Mutants in complementation group I isolated in Glasgow and 596 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest In vitro transcriptase activity of three group I temperat[r] ... See full document
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Assignment of the temperature-sensitive lesion in the replication mutant A1 of vesicular stomatitis virus to the N gene.
... 44 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The replication defect in the temperature-sensitive mutant Al of the New Jersey serotype Hazelhurst subtype of vesicu[r] ... See full document
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Regulation of viral transcription by the matrix protein of vesicular stomatitis virus probed by monoclonal antibodies and temperature-sensitive mutants.
... Enzymatically active RNP VS virions were prepared in two different forms To isolate RNP cores with M protein attached Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Th[r] ... See full document
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Location of the Transcription Defect in Group I Temperature-Sensitive Mutants of Vesicular Stomatitis Virus
... In order to locate the temperature-sensitive transcription defect in the mutants, wt and ts mutant virions were fractionated by Triton X-100-high salt solubilizer into a sedimentable rib[r] ... See full document
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RNA Synthesis in Temperature-Sensitive Mutants of Vesicular Stomatitis Virus
... REICHMANN Department of Microbiology, University of Illinois, Urbana, Illinois 61801 T-particle-free stocks of temperature-sensitive mutants representing the four Glasgow complementation[r] ... See full document
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Transcription and Replication of Vesicular Stomatitis Virus: Effects of Temperature-Sensitive Mutations in Complementation Group IV
... To observe the effect on protein synthesis, HeLa cells or CEF both infected with ts IV111 have been treated by cycloheximide 100 ,ug/ml at the time of the upward shift to 39.2 C and exte[r] ... See full document
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Preliminary Physiological Characterization of Temperature-Sensitive Mutants of Vesicular Stomatitis Virus
... Preliminary Physiological Characterization of Temperature-Sensitive Mutants of Vesicular Stomatitis Virus Different temperature-sensitive mutants of vesicular stomatitis virus have been [r] ... See full document
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Temperature-Sensitive Mutants of Vesicular Stomatitis Virus: Synthesis of Virus-Specific Proteins
... Deficient or defective proteins have been identified at nonpermissive temperatures for two of the three complementation groups of RNA+ mutants of Sindbis virus; mutants of complementatio[r] ... See full document
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