[PDF] Top 20 T cell selection in the thymus
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T cell selection in the thymus
... large T antigen under the control of class I H-2K^ promoter (H2ts m i c e ) ...the thymus in the adults. Conditionally immortalised thymic stromal cell lines were established from such hyperplastic ... See full document
262
Thymus activity measured by T cell receptor excision circles in patients with different severities of respiratory syncytial virus infection
... of T-lymphocyte activity has been associated with mechanical ventilation [18] and a longer duration of oxygen supplementation in infants with RSV infection ...in T-lymphocyte cytokines between disease ... See full document
8
Antigen-Driven T-Cell Selection in Patients with Cervical Cancer as Evidenced by T-Cell Receptor Analysis and Recognition of Autologous Tumor
... renal cell cancer (17), melanoma (19), non-small-cell lung cancer (5), and lymphoma ...single T-cell clones ...(limited) selection of a few TCR clono- types (10, ...I-restricted ... See full document
12
Expression of Mouse Mammary Tumor Virus Superantigen mRNA in the Thymus Correlates with Kinetics of Self-Reactive T-Cell Loss
... and T lymphocytes to facilitate transport of virus from the gut of newborns to mammary cells, and lymphocytes appear to be a reservoir of virus in the postnatal period prior to mam- mary gland development (7, 23, ... See full document
12
Selection for c-myc Integration Sites in Polyclonal T-Cell Lymphomas
... c-myc locus. These experiments revealed that LTRs inserted at virtually any location were capable of stimulating transcription of the c-myc promoters between 2- and 160-fold, consistent with the enhancer function of the ... See full document
13
Analyses of Lymphocytes from Patients with Rheumatoid Arthritis and Systemic Lupus Erythematosus OCCURRENCE OF INTERFERING COLD REACTIVE ANTILYMPHOCYTE ANTIBODIES
... of thymus-derived (T) cells in both diseases was slightly greater than the normal ...blood. T cells primarily accounted for this increase. The T cells typically formed unusually dense rosettes ... See full document
12
Analysis of the adult thymus in reconstitution of T lymphocytes in HIV 1 infection
... + T-cell levels of <50/mm 3 for 51 months prior to ...+ T cells after antiretroviral ...functional thymus tissue, and when present, thymopoiesis did not prevent prolonged ... See full document
9
VIP Regulates the Development & Proliferation of Treg in vivo in spleen
... and thymus were removed and placed in a Falcon tube with RPMI media and stored on ice until labeling with antibodies for flow cytometric analysis of FOXP3 and ...and thymus were teased apart and ... See full document
8
The kinesin motor protein Kif7 is required for T cell development and normal MHC expression on thymic epithelial cells (TEC) in the thymus
... SP cell, T-cell GHYHORSPHQW LQ WKH ...However, T-cells lack primary cilia, and ciliary proteins are located in the immune synapse ...that cell surface CD5 expression was reduced in ... See full document
14
Immunological surveillance against DNA-virus-transformed cells: correlations between natural killer cell cytolytic competence and tumor susceptibility of athymic rodents.
... Theoretically, additional defects, such as alterations in effector cell chemotaxis or amplification, could exist in NK-cell responses and other thymus-independent inflammatory cell respo[r] ... See full document
7
CD8+ T cell selection, function, and death in the primary immune response in vivo
... of T cells specific for the RAKFKQLL and GLCTLVAML epitopes in sam- ples of PBMCs taken during the primary immune response with that of T cells specific for these epi- topes in samples of PBMCs taken 1 year ... See full document
12
T-Lineage Specification and Commitment Requires Constraint of Myeloid Gene Expression Programs by Hes1
... of T-lineage commitment is thought to be complete by the DN2b stage, which is distinguished from the DN2a stage based on decreased levels of Kit ...undergo T-lineage specification and β -selection, ... See full document
177
Impairment of Di(2 Ethylhexyl) Phthalate on Cellular Immunity in Kunming Mice
... suppress T cell-mediated immunity in ...days. T cell-mediated immunity assessed by phytohaemagglutinin (PHA) response was depressed in the DEHP treated mice com- pared with the controls, ... See full document
7
Evidence for a stepwise program of extrathymic T cell development within the human tonsil
... human tonsil. (A) CD34-depleted cells from the human tonsil and thymus and total peripheral blood mononuclear cells were analyzed for expression of DP cells (left). DP events were then analyzed for expres- sion of ... See full document
14
Clustering the Age Classified Preprocessed Automated Blood Cell Counter Data using K Means First Distinct Element Selection and Random Selection Algorithms
... The attributes RBC, WBC, Hg count, MCH, MCHC, MCV, MPV, PCT, RDW and WBC components percentages were required for analyzing the blood cell counter data and hence the records without these fields were removed. The ... See full document
7
Analysis of Chicken T Cell Mediated Responses on Thymus after Immune Stress
... + T cells was investigated in thymus using the avidin-biotin complex (ABC) method for immunohistochemistry ...tive T cells accounted for 100 T ... See full document
7
Understanding T Cell Recovery Following Thymus Injury
... robust T lineage potential (Saran et ...the thymus at early time points, it remains possible that these progenitors either directly seed the thymus or they very rapidly seed another organ where they ... See full document
124
Combination central tolerance and peripheral checkpoint blockade unleashes antimelanoma immunity
... the thymus involutes with age, whether thymus output can be manipulated in adults for therapeutic purpose is an open ...TRP-1–specific T cells in adult mice (Supplemental Figure 5 and ...that ... See full document
14
CD117+CD44+ Stem T Cells Develop in the Thymus and Potently Suppress T-cell Proliferation by Modulating the CTLA-4 Pathway
... Thymocytes from naive mice were stained with antibody cocktail to confirm whether CD117 expression is associ- ated with CD44 expression in the other thymocyte subpop- ulations. In three experiments performed ... See full document
13
Gata3 restrains B cell proliferation and cooperates with p18 INK4c to repress B cell lymphomagenesis
... lymphoid cell differentiation and its function in T cell commitment and development has been extensively ...promotes T cell specification by repressing B cell potential in pro ... See full document
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