[PDF] Top 20 An amino-terminal domain of the Sendai virus nucleocapsid protein is required for template function in viral RNA synthesis.
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An amino-terminal domain of the Sendai virus nucleocapsid protein is required for template function in viral RNA synthesis.
... C. Nucleocapsid product RNAs were detected by Northern anal- ysis with a DI probe as described in Materials and ...DI RNA in cells transfected only with the DI-H plasmid, showing that genome amplification ... See full document
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Regulation of Viral RNA Synthesis by the V Protein of Parainfluenza Virus 5
... of viral RNA synthesis by the C terminus of V is not ...cysteine-rich domain, and sin- gle point mutations of the cysteine residues resulted in disruption of the structure of the domain ... See full document
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Zinc Finger Domain of Murine Leukemia Virus Nucleocapsid Protein Enhances the Rate of Viral DNA Synthesis in Vivo
... NC protein is generally considered to be an RNA chaperone during reverse ...processive viral DNA synthesis by destabi- lizing secondary structures has also been studied in vitro (36, 42, ... See full document
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The Amino-Terminal Domain of Bovine Viral Diarrhea Virus Npro Protein Is Necessary for Alpha/Beta Interferon Antagonism
... by RNA viruses, involve the production of cRNA molecules in the form of extended dsRNA ...uncharacterized viral signals, activates a cascade of events that converge to activate several transcription ... See full document
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Mutations in the N-terminal domain of human immunodeficiency virus type 1 nucleocapsid protein affect virion core structure and proviral DNA synthesis.
... the viral core. NCp7 molecules are tightly associated with the genomic RNA dimer to form the nucleocapsid, which also includes reverse transcriptase and integrase ...HIV-1 RNA, inducing ... See full document
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Measles Virus Phosphoprotein Gene Products: Conformational Flexibility of the P/V Protein Amino-Terminal Domain and C Protein Infectivity Factor Function
... enveloped virus with a nonsegmented negative-strand RNA genome belonging to the Morbillivirus genus of the Paramyxoviridae family ...species Sendai virus (SeV), is tightly encapsidated by ... See full document
9
The C-Terminal 88 Amino Acids of the Sendai Virus P Protein Have Multiple Functions Separable by Mutation
... genome RNA, which is then nonspecifically encapsidated by the NP protein encoded by ...the viral polymerase with multiple rounds of amplification required to detect ...genome RNA as ... See full document
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The Amino-Terminal Domain of Alphavirus Capsid Protein Is Dispensable for Viral Particle Assembly but Regulates RNA Encapsidation through Cooperative Functions of Its Subdomains
... of viral particles, which have provided the field with a detailed knowledge of the structures of alphavirus glycoprotein spikes and their interactions with ...of viral RNA replication, and then are ... See full document
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Interaction of the Influenza A Virus Nucleocapsid Protein with the Viral RNA Polymerase Potentiates Unprimed Viral RNA Replication
... NP protein potentiates the synthesis of cRNA, the first step in viral RNA replication, in the absence of a ...vRNA synthesis using purified recombi- nant ...cRNA synthesis, we ... See full document
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Newly Identified Phosphorylation Site in the Vesicular Stomatitis Virus P Protein Is Required for Viral RNA Synthesis
... P protein to support both transcription and replication indicates that either this Tyr residue or phosphorylation at this site affects a fundamental function of P with the ...not required for ... See full document
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Cytoplasmic Domain of Sendai Virus HN Protein Contains a Specific Sequence Required for Its Incorporation into Virions
... Sendai virus (SV), a prototype paramyxovirus, encodes at least six structural proteins: the two viral membrane glycopro- teins HN and F, which are responsible for virus attachment, ... See full document
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Identification of Sendai Virus L Protein Amino Acid Residues Affecting Viral mRNA Cap Methylation
... polymerase protein responsible for the replication and transcription of the viral genome as well as all posttranscriptional modifications of viral ...L protein is conserved among all members ... See full document
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Single-Amino-Acid Alterations in a Highly Conserved Central Region of Vesicular Stomatitis Virus N Protein Differentially Affect the Viral Nucleocapsid Template Functions
... disease virus, rhabdovirus, and influenza A virus, suggests a very similar organizational pattern, having at least five conserved helices in the amino-terminal domain and three ... See full document
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Genetic analysis of a hydrophobic domain of coxsackie B3 virus protein 2B: a moderate degree of hydrophobicity is required for a cis-acting function in viral RNA synthesis.
... B virus protein 2B contains near its C terminus a hydrophobic domain with an amino acid composition that is characteristic for transmembrane ...this domain in virus reproduction ... See full document
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The Amino-Terminal Half of Sendai Virus C Protein Is Not Responsible for either Counteracting the Antiviral Action of Interferons or Down-Regulating Viral RNA Synthesis
... be required for pathogenesis at an acute phase of infection and also for the establishment of persistent infection in cultured cells or ...Y2 protein equally circumvent the antiviral action of alpha/ beta ... See full document
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A Role for the Sendai Virus P Protein Trimer in RNA Synthesis
... P protein, the vesicular stomatitis virus (VSV) P protein is found as an oligomer, possibly a trimer (14), although there are clearly differences in the ways these struc- tures ...P protein ... See full document
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Sequence in the Influenza A Virus Nucleoprotein Required for Viral Polymerase Binding and RNA Synthesis
... is required for viral RNA synthesis as determined in minigenome ...is required for viral RNA ...the RNA-binding groove (15, ...(Ud) virus in each of these ... See full document
6
Andes Virus Nucleocapsid Protein Interrupts Protein Kinase R Dimerization To Counteract Host Interference in Viral Protein Synthesis
... the synthesis of globin peptides in response to elevated heme ...Andes virus at an MOI of 1, followed by transfection with either empty vector or a plasmid expressing N-terminally Myc-tagged PKR at 24 h ... See full document
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Amino-Terminal Precursor Sequence Modulates Canine Distemper Virus Fusion Protein Function
... cleaved. Protein maturation continues during transport through the ER and Golgi apparatus to the cell surface (re- viewed in reference ...The amino-terminal part ranges in length between 8 and more ... See full document
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Non structural protein 1 is required for West Nile virus replication complex formation and viral RNA synthesis
... While the ability of ectopically-expressed NS1 to trans- complement flaviviruses (WNV or YFV) containing gene deletions in NS1 has been demonstrated previously [22,25], our studies show uniquely for WNV that heterol- ... See full document
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