[PDF] Top 20 Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C).
Has 10000 "Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C)." found on our website. Below are the top 20 most common "Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C).".
Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C).
... the APC/C on cessation of SAC signalling ...the APC/C generates canonical Lys48-linked chains also using two E2s: the initiating E2 Ubc4 and the elongating E2 Ubc1 ...the APC/C ... See full document
27
The Anaphase-Promoting Complex/Cyclosome Is Required for Anaphase Progression in Multinucleated Ashbya gossypii Cells
... The anaphase-promoting complex/cyclosome (APC/C) is responsible for the protein destruction required for the initiation of anaphase and the exit from mitosis, including ... See full document
16
Studies on the Contribution of Human Cytomegalovirus UL21a and UL97 to Viral Growth and Inactivation of the Anaphase-Promoting Complex/Cyclosome (APC/C) E3 Ubiquitin Ligase Reveal a Unique Cellular Mechanism for Downmodulation of the APC/C Subunits APC1, APC4, and APC5
... the APC/C was shown to be more growth im- paired than a double mutant that contained a UL97 deletion and UL21a point mutations where UL21a was still able to degrade APC4 and APC5 (19), suggesting that ... See full document
12
Asymmetric localisation of Miranda and its cargo proteins during neuroblast division requires the anaphase promoting complex/cyclosome
... Ubiquitylation is clearly an important aspect of the Miranda localisation process, but in its absence a proportion of the Miranda present in the NB can be localised at the basal cortex by other mechanisms. Hence, ... See full document
7
APC/C-Cdh1-dependent anaphase and telophase progression during mitotic slippage
... inhibits anaphase progression in the presence of insufficient kinetochore-microtubule attachments, but cells can eventually override mitotic arrest by a process known as mitotic slippage or ...of anaphase ... See full document
15
Apoptin Nucleocytoplasmic Shuttling Is Required for Cell Type-Specific Localization, Apoptosis, and Recruitment of the Anaphase-Promoting Complex/Cyclosome to PML Bodies
... requires APC/C ...the APC/C ...Apoptin, APC/C would be present in PML ...the C terminus of cyan fluo- rescent protein ...the APC/C becomes sequestered in PML ... See full document
11
In Vivo Characterization of the Nonessential Budding Yeast Anaphase-Promoting Complex/Cyclosome Components Swm1p, Mnd2p and Apc9p
... Figure 1.—Identification of SWM1 and MND2 as new budding yeast APC/C components. (A) Terminal arrest phenotype of apc1-21. Upon shift to 37⬚ for 3 hr, the majority of apc1-21 cells (YVA1098) arrest with ... See full document
18
Nuclear pore protein NUP88 activates anaphase promoting complex to promote aneuploidy
... the anaphase-promoting complex/ cyclosome (APC/C) coactivator ...and anaphase onset by inhibiting APC/C CDC20 -mediated ... See full document
18
Orthologues of the Anaphase-Promoting Complex/Cyclosome Coactivators Cdc20p and Cdh1p Are Important for Mitotic Progression and Morphogenesis in Candida albicans
... potential APC/C func- tion in ...inhibit anaphase pro- gression, but this is thought to act in concert with securin and/or compensate for its loss (32, 33, ... See full document
14
The function of APC/CCdh1 in cell cycle and beyond
... and APC/C (anaphase promoting complex/ cyclosome), control the timely transitions of cell cycle phases by promoting the degradation of many key cell cycle ...SCF ... See full document
7
Multiple Subunits of the Caenorhabditis elegans Anaphase-Promoting Complex Are Required for Chromosome Segregation During Meiosis I
... the anaphase-promoting complex or cyclosome ...other APC/C subunits are essential for the segregation of chromosomal homologs during meiosis ...requires APC/C ... See full document
9
Mechanisms for the temporal regulation of substrate ubiquitination by the anaphase-promoting complex/cyclosome
... regulating APC/C activity and mitosis exit, and serves as a molecu- lar switch to convert BUBR1 from an APC/C inhibitor, to a substrate of APC/C complex (with CDC20 in ... See full document
18
Changes in the Localization of the Saccharomyces cerevisiae Anaphase-Promoting Complex Upon Microtubule Depolymerization and Spindle Checkpoint Activation
... The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase in the ubiquitin-mediated proteolysis pathway ...the APC/C was targeted to its ... See full document
16
Emerging role of F-box proteins in the regulation of epithelial-mesenchymal transition and stem cells in human cancers
... APC/C: Anaphase-promoting complex or cyclosome; CASC2: Cancer susceptibility candidate 2; CRL: Cullin-RING E3 ligase; CRPC: Castration- resistant prostate cancer; CSCs: Cancer ... See full document
11
Accumulation of Substrates of the Anaphase-Promoting Complex (APC) during Human Cytomegalovirus Infection Is Associated with the Phosphorylation of Cdh1 and the Dissociation and Relocalization of APC Subunits
... the anaphase-promoting complex (APC), a multisubunit E3 ubiquitin ligase, and accumulation of its ...the APC from infected cells indicates that the core APC also may be ...core ... See full document
9
The Anaphase Promoting Complex Regulates Yeast Lifespan and rDNA Stability by Targeting Fob1 for Degradation
... cellular functions that involve the APC also continues to ...These functions include maintenance of genomic stability and control of chromatin ...that APC mutants result in loss of chromosomes ... See full document
17
A Functional Analysis Reveals Dependence on the Anaphase-Promoting Complex for Prolonged Life Span in Yeast
... accumulation APC-dependent aging pathway that we have character- of ERCs (Sinclair et ...the mechanisms control- was found to be synthetically lethal when combined ling life-span determination in higher ... See full document
16
Contribution of CAF-I to Anaphase-Promoting-Complex-Mediated Mitotic Chromatin Assembly in Saccharomyces cerevisiae
... cerevisiae APC is required for longevity ...the APC plays a pivotal role in resistance to cancer (5, 53, ...the mechanisms employed by the APC to control chromatin assembly in ... See full document
12
Control the Host Cell Cycle: Viral Regulation of the Anaphase-Promoting Complex
... ligase anaphase-promoting complex (APC) that targets effector proteins for ubiquitination and proteasome ...The APC is essential for cells to progress through anaphase, exit from ... See full document
8
Antagonistic Gcn5-Hda1 interactions revealed by mutations to the Anaphase Promoting Complex in yeast
... in APC function, as altered expression of APC regulators may underlie the observed growth phe- ...in APC activity, whereas Pds1, Bcy1 and Mad2 have a negative impact ... See full document
16
Related subjects