Association Mapping
A two-stage microbial association mapping framework with advanced FDR control
... OMiAT-HBH, OMiAT-SST, and traditional BH methods each identified 15 ABH-associated species, among which 14 species are common (Table 1). In contrast, AGG-HBH and AGG-SST only identified five ABH associated species due to ...
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An Association Mapping Framework To Account for Potential Sex Difference in Genetic Architectures
... Although we tried to account for many possible phenom- ena that can occur due to the sex difference in genetic association mapping, our model might still have limitations. In our method, we explicitly ...
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Mapping Some Seed Quality Traits in Bread Wheat (Triticum aestivum L.) by Association Mapping Using SSR Markers
... targeted association mapping of seed quality ...an association between markers and traits, Q-matrix, quality traits matrix, and scored SSR markers matrix were tested using the mixed linear model ...
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Density based clustering in haplotype analysis for association mapping
... We combined the density-based clustering algorithm of Li and Jiang [1] with the general linear model (GLM) approach of Schaid et al. [2,3] for association mapping. Based on real pedigrees and SNPs, the ...
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Multipoint association mapping for longitudinal family data: an application to hypertension phenotypes
... Gene-based association mapping was conducted for all SNPs on chromosome 3. This approach accounts for correlations between markers and repeated phenotypes within subjects, and correlations between subjects ...
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Resistance to greenbugs in the sorghum nested association mapping population
... The greenbug, Schizaphis graminum, is a serious pest of sorghum (Sorghum bicolor). For the past several decades, resistant sorghum hybrids have been used to control greenbug populations. However, the durability of plant ...
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Combined Linkage and Association Mapping of Quantitative Trait Loci by Multiple Markers
... (LD) mapping or associa- using two markers are proposed for high-resolution link- tion study, one may use one marker a ...and association mapping of quantitative trait loci the resolution of the ...
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Recovering Power in Association Mapping Panels with Variable Levels of Linkage Disequilibrium
... genome-wide association stud- ies (GWAS), in which phenotypes and genotypes of individ- uals in highly diverse panels are used to detect QTL (Lynch and Walsh ...linkage mapping, more markers are therefore ...
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A powerful microbiome-based association test and a microbial taxa discovery framework for comprehensive association mapping
... group association testing method, optimal microbiome-based association test ...kernel association test ...significant association signals arising from varying microbial abundances and ...
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Genetic Association Mapping of Agronomic, Fruit Quality, and Metabolic Traits in Blueberry and Broccoli.
... improves the stability of anthocyanins (Horbowicz et al., 2008; Jia et al., 2017; Khoo et al., 2017; Koyama et al., 2010; Majda & Robert, 2018; Ozga & Reinecke, 2003; Perrot- Rechenmann, 2010; Wahyuningsih et ...
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Rapid and robust association mapping of expression quantitative trait loci
... Association mapping is commonly used in detecting quantitative trait loci ...wide association of multiple quantitative traits (such as global gene expression) due to the need to solve a large number ...
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Association mapping to dissect and exploit existing natural variation for crop improvement
... genetic mapping is called quantitative trait loci mapping ...such mapping populations in all crop ...the association mapping technique is ...based mapping association ...
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Assessment of gene covariate interactions by incorporating covariates into association mapping
... multipoint association mapping approach using case-control ...the mapping, in order to estimate τ more ...our association mapping to estimate the disease locus for RA and to assess ...
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Strategies for haplotype-based association mapping in a complex pedigreed population
... genome-wide association studies that used simulated or real data investigated the power and precision of QTL findings ...QTL mapping, but did not compare type I ...in association mapping has ...
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Association mapping via a class of haplotype sharing statistics
... We present a class of haplotype-sharing statistics useful for association mapping in case-parent trio data. The framework presented allows derivation of novel tests as well as new simplified variance ...
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High-Resolution Association Mapping of Quantitative Trait Loci: A Population-Based Approach
... LD mapping and a linkage study of QTL by variance component models in the spirit of our previous ...that association study-based population data are prone to false positives, due to the population ...
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Linkage disequilibrium maps and association mapping
... Association mapping localizes genes affecting disease suscep- tibility or other phenotypes through association with nearby polymorphisms, usually ...Often association mapping is ori- ...
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Association mapping of susceptibility loci for rheumatoid arthritis
... for association mapping under the framework of the Malecot model and composite likelihood, we identified a region showing significant association with RA (p < ...significant association ...
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Association mapping of major starch biosynthesis genes in Zea mays ssp. mays.
... an association approach: Amylose extender1 (Ae1), Brittle endosperm2 (Bt2), Shrunken1 (Sh1), Shrunken2 (Sh2), Sugary1 (Su1), and Waxy1 ...linkage mapping studies implicating the Sh2 chromosomal region in ...
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Impact of marker density on the accuracy of association mapping
... We studied the impact of marker density on the accuracy of association mapping using Genetic Analysis Workshop 15 simulated dense single-nucleotide polymorphism (SNP) data on chromosome 6. A total of 1500 ...
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