Metformin HCL
FORMULATION AND EVALUATION OF BILAYER TABLETS OF METFORMIN HCL AND PIOGLITAZONE HCL
... and Metformin hydrochloride for sustained release using EUDRAGIT ESPO as matrix forming ...of Metformin hydrochloride was evaluated using the regression coefficient ...of Metformin HCl matrix ...
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DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF GLIBENCLAMIDE AND METFORMIN HCL IN BULK AND TABLETS USING UV – VISIBLE SPECTROSCOPY
... Two simple, precise and economical UV methods have been developed and validated for the simultaneous estimation of Glibenclamide and Metformin hydrochloride in bulk and pharmaceutical combined dosage form. The ...
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FORMULATION AND EVALUATION OF FLOATING MATRIX TABLETS OF METFORMIN HCl FOR THE TREATMENT OF TYPE 2 DIABETES MELLITUS
... CONCLUSION: Floating matrix tablets of Metformin HCl with HPMC K15M and Carbopol 934P were prepared and optimized using central composite statistical design. The quantitative effect of these factors at ...
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FORMULATION AND OPTIMIZATION OF SUSTAINED RELEASE MATRIX TABLET OF METFORMIN HCL 500 MG USING RESPONSE SURFACE METHODOLOGY
... forms. Metformin HCL, the only available biguanide, remains the first line drug therapy for patients with Type 2 diabetes mellitus (T2DM), acts by decreasing hepatic glucose output and peripheral insulin ...
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Gamma scintigraphic evaluation of floating gastroretentive tablets of metformin HCl using a combination of three natural polymers in rabbits
... Abstract: The present research was aimed at formulating a metformin HCl sustained- release formulation from a combination of polymers, using the wet granulation tech- nique. A total of 16 formulations ...
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STABILITY INDICATING CHROMATOGRAPHIC METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF METFORMIN HCl & ANAGLIPTIN IN ITS SYNTHETIC MIXTURE BY HPLC
... drug Metformin HCl and Anagliptin preferably analyzed by reverse phase columns and accordingly C18 column was selected so the elution of the compound from the column was influenced by polar mobile ...for ...
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Density, Viscosity and Refractive Index Studies of Metformin HCl in Aqueous System at 303.15K.
... The densities, viscsity and refractive indices of Metformin HCl in aqueous system at different concentrations and at temperature of 303.15K were measured. These physicochemical properties were further used ...
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DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF SAXAGLIPTIN AND METFORMIN HCl BY USING RP-HPLC METHOD
... drug. Metformin HCl is 1-carbamimidamido-N,N-dimethylmethanimidamide and used as anti-diabetic ...and Metformin HCl revealed several methods based on techniques ...and Metformin ...
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FORMULATION EVALUATION AND OPTIMIZATION OF METFORMIN HCl MATRIX TABLET USING NATURAL POLYMER
... Tablets: Metformin HCl tablets were prepared by wet granulation ...of Metformin HCl was prepared by using drug Metformin HCl, HPMC-K-100, PVP-K-30, microcrystalline cellulose, ...
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DEVELOPMENT AND VALIDATION OF RP HPLC METHOD FOR ESTIMATION OF ANTIDIABETIC DRUGS ALOGLIPTIN BENZOATE AND METFORMIN HCL IN PHARMACEUTICAL FORMULATION
... mixture of Methanol: 10 mM potassium dihydrogen phosphate pH 2.5 in the ratio 30:70 as mobile phase, at a flow rate of 1.0 ml/min. UV detection was performed at 224 nm. The method was validated according to ICH ...
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STABILITY INDICATING RP – HPLC METHOD FOR DETERMINATION OF GLIBENCLAMIDE & METFORMIN HCL IN PURE AND PHARMACEUTICAL FORMULATION
... A simple, rapid and accurate and stability indicating RP-HPLC method was developed for the determination of Glibenclamide & Metformin HCL in pure and tablet forms. The method showed a linear response ...
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Development and validation of TLC densitometry method for simultaneous determination of metformin HCl and glibenclamide in tablets dosage form
... of metformin HCl, including HPLC [4-11] and spectrophotometry ...mixed metformin HCl and glibenclamide in tablet dosage forms ...mixed metformin HCl and glibenclamide in tablet ...
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FIRST ORDER DERIVATIVE SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF ANAGLIPTIN AND METFORMIN HCl IN BULK AND SYNTHETIC MIXTURE
... of Metformin HCl & Anagliptin in bulk drug and syntheticmixture without any interference from the ...of Metformin HCl & Anagliptin in ...
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ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF ERTUGLIFLOZIN AND METFORMIN HCl IN BULK AND PHARMACEUTICAL DOSAGE FORM BY HPLC
... and Metformin hydrochloride (MET) was developed and validated by high-performance liquid chromatography (HPLC) as per ICH ...and Metformin hydrochloride ...
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DEVELOPMENT AND VALIDATION OF RP HPLC AND UV DERIVATIVE SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF METFORMIN HCL AND PIOGLITAZONE IN PHARMACEUTICAL FORMULATIONS
... Tetrahydrofuran in the ratio of 70:30%v/v at a flow rate of 1ml/min. The drugs were monitored at 230 nm. The retention time of Metformin HCl and Pioglitazone were found to be 1.02 and 2.51min respectively. ...
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Development and validation of uv spectrophotometric method for the determination of metformin hcl, rosuvastatin calcium and telmisartan in bulk drug
... for Metformin HCl, Rosuvastatin Calcium and Telmisartan ...of Metformin HCl, Rosuvastatin Calcium and Telmisartan was proved by ...of Metformin HCl, Rosuvastatin Calcium and ...
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DEVELOPMENT AND VALIDATION OF CHROMATOGRAPHIC AND SPECTROSCOPIC METHODS FOR ESTIMATION OF REPAGLINIDE AND METFORMIN HCl IN COMBINED DOSAGE FORM
... The proposed study describes an HPLC and second derivative spectrophotometric methods for estimation of repaglinide and metformin HCl in bulk or in their combination. The methods were validated and found to ...
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Development and Validation of RP-HPLC method for the simultaneous estimation of Miglitol and Metformin Hcl in Pharmaceutical formulations
... routine analysis in research institutions, quality control department in industries, approved testing laboratories, bio-pharmaceutics and bio- equivalence studies and in clinical pharmacokinetic studies. The method ...
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Stability Indicating Method Development and Validation for Simultaneous Estimation of Linagliptin and Metformin HCl in Tablets by HPLC
... A new RP-HPLC method has been developed for simultaneous estimation of linagliptin and metformin HCl in marketed formulation. The method showed good resolution between the two drugs and also with degradants ...
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Article: Formulation and evaluation of metformin HCl floating microspheres
... pure metformin HCl which indicates that metformin HCl is compatible with the ...of metformin HCl may prove to be potential candidate for safe and effective sustained drug ...
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