Protein-Protein Interaction
Modular organization in the reductive evolution of protein protein interaction networks
... throughput protein interaction maps of ...Buchnera interaction networks was based on the assumed low rate of protein interaction turnover [16] and the weak probability that new ...
8
High throughput protein-protein interaction data: clues for the architecture of protein complexes
... TATA-binding protein and other transcrip- tion factors [34,35] It has three distinct functional modules [26,28,35,36] along with other associated pro- ...put protein-protein interaction ...
9
HMNPPID—human malignant neoplasm protein–protein interaction database
... their protein–protein interactions [21], which was constructed by combining proteins from seven KEGG (Kyoto Encyclopedia of Genes and Ge- nomes) 14 [22] classical cancer-associated signaling pathways ...
10
Evolution of protein-protein interaction networks in yeast
... of protein-protein and genetic interaction networks has been rising in recent years, but the lack of large-scale high quality comparative datasets has acted as a ...predicted protein- ...
21
Protein-protein interaction databases: keeping up with growing interactomes
... known protein – protein interactions has increased ...store protein – protein interaction data. Protein – protein interactions have been retrieved from six major ...
7
Detecting Protein Complexes by an Improved Affinity Propagation Algorithm in Protein-Protein Interaction Networks
... of protein complexes in protein-protein interaction (PPI) networks is important in understanding cellular ...discover protein complexes with high precision by compared with the AP, MCL, ...
8
Construction and analysis of protein-protein interaction network associated with human sperm-egg interaction
... identify protein-protein interaction between human sperm and egg (Evans, ...of protein complexes, many efforts have failed to comprehensively elucidate the fusion mechanism and the molecular ...
44
Systematic protein protein interaction and pathway analyses in the idiopathic inflammatory myopathies
... explored. Protein-protein interaction (PPI) analyses have been performed in a number of complex diseases, including breast cancer, schizophrenia and mul- tiple sclerosis ...
13
DIFFERENT APPROACHES FOR STUDYING PROTEIN PROTEIN INTERACTION AND ANALYSIS
... in protein and protein networking databases gives the first insight to study such macromolecular interactions paving the way for their in-vitro and in-vivo ...the protein-protein ...
20
Construction of Protein Protein Interaction Network Using Community Molecular Detection
... The number of proteins continues grow. Machine learning is a subfield of computer science that includes the study of systems that can learn from data, rather than follow only explicitly programmed instructions. Some of ...
12
Reciprocal Perspective for Improved Protein-Protein Interaction Prediction
... of protein-protein interaction net- works: Reciprocal Perspective (RP), which jointly considers an interaction from the perspective of each partner to determine a new assessment of the ...that ...
12
Fitting a geometric graph to a protein-protein interaction network
... for protein–protein interaction (PPI) networks is a fundamental ...PPI interaction data and embeds proteins into a low-dimensional Euclidean space, under the premise that connectivity ...
7
CoreAlign: Core based Global Alignment for Protein Protein Interaction Networks
... Nowadays, the real-world phenomenon of binding proteins to each other plays a powerful roll in configuring how cells work together to perform various functions. This progress helps in disease and drug discovery and gives ...
7
Algorithmic approaches to protein-protein interaction site prediction
... on protein surfaces mediate virtually all biological activities, and their identification holds promise for disease treatment and drug ...modern protein-protein interaction site (PPIS) ...
21
Construction and Analysis of Tissue-Specific Protein-Protein Interaction Networks in Humans
... Studying Protein- Protein Interaction Networks (PINs) on a genome-scale has become possible through advances in high-throughput experimental ...of interaction data for several species ...
13
A Study on Dependency Tree Kernels for Automatic Extraction of Protein Protein Interaction
... the protein-protein interaction (PPI) extraction task on the AIMed corpus show that tree kernels based on our proposed DT struc- tures achieve higher accuracy than previously proposed DT and phrase ...
10
Characterization of Protein Interfaces to Infer Protein-Protein Interaction
... of interaction of two key macromolecular species is one of the major problems in structural and molecular ...of protein – protein interactions depend upon knowledge of both the three dimensional ...
5
Comparison of computational tools for protein-protein interaction (PPI) mapping and analysis
... the protein-protein interaction data from the two databases and displays it in its network ...create protein-protein interaction network by manually typing in the information in ...
8
Complex tree: the basic framework of protein protein interaction networks
... determined protein-protein interaction data was ut- ilized as the input ...the Protein-Protein Interactions with binary relations data from DIP, version DIP_20081014 ...
7
A New Algorithm for Protein-Protein Interaction Prediction
... Currently, the understanding of protein-protein interaction (PPI) networks is far from satisfactory. Even for very small organisms, the ratio between known and potential PPIs is about 1:500 [15, 40]. ...
57