[PDF] Top 20 The Effect of Strong Purifying Selection on Genetic Diversity
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The Effect of Strong Purifying Selection on Genetic Diversity
... than selection can purge them and there will be substantial fitness variation at the ...of selection against the allele depends on the average num- ber of deleterious mutations that the individuals that ... See full document
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Genetic diversity and selection of common bean lines based on technological quality and biofortification.
... is genetic dissimilarity, especially for cooking time (G3), calcium concentration (G2), and iron concentration ...inhibitory effect on iron and zinc absorption by the body (Ariza-Nieto et ... See full document
13
Disjunct Populations of a Locally Common North American Orchid Exhibit High Genetic Variation and Restricted Gene Flow
... higher genetic diversity in Pogonia ophioglossoides as compared to other common terre- strial orchids that used nSSR markers ...of genetic variation observed in ...high genetic ... See full document
17
Finding the Factors of Reduced Genetic Diversity on X Chromosomes of Macaca fascicularis: Male-Driven Evolution, Demography, and Natural Selection
... X/A genetic diversity near CDS in the whole-genome sequence data is much weaker than that in our 10-locus ...of purifying selection (Lu and Wu 2005), the natural selection on the genes ... See full document
17
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... under strong purifying selection, indi- cating that host immune responses targeting these antigens might not be ...human genetic diversity might help identify additional targets that ... See full document
6
Genetic diversity as an additional selection criterion in a carioca common bean recurrent selection program for resistance to common bacterial blight
... genotype effect, indicating genetic variability and thus justifying selection for superior genotypes since there is the possibility of obtaining genetic gains for these traits (Table ...the ... See full document
15
Hill-Robertson Interference Reduces Genetic Diversity on a Young Plant Y-Chromosome
... in strong linkage disequilibrium, making them vulnerable to diversity loss due to selection against strongly deleterious mutations (background selection; Charlesworth et ...of genetic ... See full document
11
Natural Selection and Genetic Diversity in the Butterfly Heliconius melpomene
... natural selection on linked sites. Selection acting on one locus can cause the removal of genetic variation at physically linked, neutral ...ground selection”) (Charlesworth et ...neutral ... See full document
67
An Important Role for Purifying Selection in Archaeal Genome Evolution
... population genetic theory ...undergo strong purifying selection owing to a generally large effective population size to maintain compact genomes ...weak purifying selection, ... See full document
5
Breeding Strategies Based on Diversity Analysis in Advance Breeding Lines of Chilli (Capsicum annuum var. annuum L.)
... the genetic variance is expected to derive mainly from additive ...Therefore, selection of genotypes as superior and diverse parents for hybridization programme should be based on diverse ...detect ... See full document
11
Understanding rare and common diseases in the context of human evolution
... of genetic information generated in the last ten years, thanks largely to the publication of se- quencing datasets for both modern human populations and ancient DNA samples [14 – 18], is making it possible to ... See full document
14
The effects of purifying selection on patterns of genetic differentiation between Drosophila melanogaster populations.
... (hereafter the SI sites), to retain sites under the least amount of selective constraint (Halligan and Keightley, 2006; Parsch et al., 2010). This left us with 7483 autosomal and 752 X-linked short introns, and 8851 ... See full document
13
Strong purifying selection in endogenous retroviruses in the saltwater crocodile (Crocodylus porosus) in the Northern Territory of Australia
... Exogenous retroviruses and their endogenous counter- parts comprise a large and diverse family that can be divided into seven genera: Alpharetrovirus, Betaretro- virus, Gammaretrovirus, Deltaretrovirus, Epsilonretro- ... See full document
11
Effects of Natural Selection on Interpopulation Divergence at Polymorphic Sites in Human Protein-Coding Loci
... gene diversity (heterozygosity) at 2000; Schork et ...the genetic contribu- where SNPs caused amino acid changes, particularly those tion to complex diseases such as cancer and heart disease, predicted to ... See full document
8
Distortions in Genealogies due to Purifying Selection and Recombination
... weak purifying selection, but only in the purely asexual ...sequence diversity are identical to the effects of fewer strongly selected mutations, making it possible to “map” weakly selected ... See full document
16
Leaf traits drive plant diversity effects on litter decomposition and FPOM production in streams
... negative effect of plant diversity loss on litter decomposition [11] and with the only available study reporting a negative effect of plant diversity loss on FPOM production to our knowledge ... See full document
16
Stabilizing Selection, Purifying Selection, and Mutational Bias in Finite Populations
... influence selection on codon usage (Plotkin and Kudla 2011), and their relative importance is ...stabilizing selection model is that the GC content of a message may increase its folding energy, so that ... See full document
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Baculovirus Molecular Evolution via Gene Turnover and Recurrent Positive Selection of Key Genes
... found strong founder effects, population structure, and low diversity due to positive selection, all of which have helped to shape our understanding of (i) how viruses adapt to host systems, (ii) ... See full document
22
Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy
... no selection of advantageous amino acids was observed, multiple silent transitional substitutions, which were present at >1% in the initial patient serum or donor inoculum, became dominant in the population ... See full document
23
A Conservative Test of Genetic Drift in the Endosymbiotic Bacterium Buchnera: Slightly Deleterious Mutations in the Chaperonin groEL
... that genetic drift and the accumulation of slightly deleterious mutations can explain this rate ...for strong purifying selection on groEL, our intraspecific analysis of this gene documents ... See full document
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