[PDF] Top 20 Formulation and Evaluation of Hydroxypropyl Methylcellulose-based Controlled Release Matrix Tablets for Theophylline

... ratio. Theophylline was procured from Amratlal and Co. Chennai. Hydroxypropyl methylcellulose (HPMC K100M) a hydrophilic polymer and magnesium stearate a glidant and antiadherent was procured from ... See full document

... Bioadhesive drug delivery systems (BDDS) are used as a delivery device within the lumen toenhance drug absorption in a site specific manner. This approach involves the use of bioadhesivepolymers, which can adhere to the ... See full document

... Controlled release tablet will provide a long lasting and more reliable release of drug in GIT to develop a once daily ...1 Theophylline is an oral bronchodilator medicine which is prescribed ... See full document

... sustained release matrix tablets of ...sustained release matrix tablets using polymer such as hydroxyl propyl methyl cellulose (HPMC) and xanthan ...The tablets were ... See full document

... to release the medication in a prolonged rate to maintain plasma drug ...drug release profile in matrix systems by different ...of matrix tablet as a sustained release had made a new ... See full document

... acetate based excipient for directly compressible matrix tablets by direct compression has attracted much attention due to its technological simplicity in comparison with other controlled ... See full document

... independent controlled release matrix tablet containing mannitol based quaternary inclusion complex (QIC) of domperidone (DOM) for the treatment of diabetic ...The tablets were prepared ... See full document

... Extended release hydrophilic matrix tablet formulations of cefuroxime axetil were developed and evaluated to observe the effect of different high viscosity hydroxypropyl methylcellulose ... See full document

... extended release of drug were originally developed to reduce or eliminate unwanted effects such as gastrointestinal disturbances, nausea, and vomiting; the short half life of the drug also indicates the need for ... See full document

... polymers. Controlled release polymeric systems are the most promising as they increase efficacy of drugs substance and reduced undesirable side ...of formulation variables available to control the ... See full document

... bilayer tablets of Salbutamol sulphate with sustained drug release can be successfully prepared by direct compression method using HPMC3 cps, HPMC5cps, HPMC K4M, HPMC K15M along with Carbopol 940 as ... See full document

... [1][2] Controlled release dosage forms have number of advantages over conventional dosage forms, such as improved patience compliance due to decrease in dosing frequencies, reduction in fluctuation in ... See full document

... In-vitro release data various kinetic models were ...drug release rate is independent of its ...the release from system where release rate is concentration ...the release of drugs from ... See full document

... drug release was more by diffusion and less by ...and release rate of NA. Increase in the amount of gum in the formulation from 50%w/w to 150%w/w, resulted in slower rate, and decreased the amount of ... See full document

... mg theophylline in matrix-type tablets were prepared by direct compression method using two kinds of matrices – glycerylbehenate (hydrophobic) and hydroxypropylmethyl cellulose ...vitro ... See full document

... is based on its preferential inhibition of Type II 5a-reductase through the formation of a stable complex with the ...control release tablets are prepared by using excipients magnesium stearate, ... See full document

... formulate controlled release matrix tablets of miglitol using three retardants namely hydroxypropyl methylcellulose used as primary rate controlling polymer and effect on in ... See full document

... oral controlled release lamivudine matrix tablets using hydroxypropyl methylcellulose (HPMC) as the retardant polymer, sodium alginate, acacia gum to study the effect of various ... See full document

... The evaluation results confirmed that the prepared tablets have exhibited satisfactory physicochemical properties such as weight uniformity, thickness uniformity, friability, hardness and drug content ...of ... See full document

... various matrix tablets is indicated in table 2. The formulated matrix tablets released the drug for 24 hours and follow near zero order release (formulations: F1, F4, F5 to F7, F9 to ... See full document