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[PDF] Top 20 Identification of protein complexes from multi-relationship protein interaction networks

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Identification of protein complexes from multi-relationship protein interaction networks

Identification of protein complexes from multi-relationship protein interaction networks

... a multi-relationship protein interaction net- work by integrating PPI networks and GO annotation ...the multi- relationship network, we design a new method for pre- ... See full document

10

Ontology integration to identify protein complex in protein interaction networks

Ontology integration to identify protein complex in protein interaction networks

... that identification of protein complexes is useful to explain certain biological progress and to pre- dict functions of ...identify protein complexes based on the new large weighted ... See full document

10

FAC-PIN: An efficient and fast agglomerative clustering algorithm for protein interaction networks to predict protein complexes and functional modules

FAC-PIN: An efficient and fast agglomerative clustering algorithm for protein interaction networks to predict protein complexes and functional modules

... or protein complexes in protein interaction ...PINs from different species for validating functional modules and protein complexes generated from FAC-PIN with ... See full document

85

Detecting Protein Complexes by an Improved Affinity Propagation Algorithm in Protein-Protein Interaction Networks

Detecting Protein Complexes by an Improved Affinity Propagation Algorithm in Protein-Protein Interaction Networks

... Abstract— Identification of protein complexes in protein-protein interaction (PPI) networks is important in understanding cellular ...discover protein ... See full document

8

A graph modification approach for finding core–periphery structures in protein interaction networks

A graph modification approach for finding core–periphery structures in protein interaction networks

... PPI networks is the identification of protein complexes and functional ...that complexes in a PPI network are strongly connected among them- selves and weakly connected to other ... See full document

13

Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein 2 Interacts with a Host Protein Complex Involved in Mitochondrial Biogenesis and Intracellular Signaling

Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein 2 Interacts with a Host Protein Complex Involved in Mitochondrial Biogenesis and Intracellular Signaling

... the protein expression profile under these conditions, we pursued a purification strategy to isolate nsp-containing complexes from SARS-CoV-infected ...isolating protein complexes ... See full document

5

Identification of RNA-Protein Interaction Networks Involved in the Norovirus Life Cycle

Identification of RNA-Protein Interaction Networks Involved in the Norovirus Life Cycle

... Cellular nucleic acid-binding proteins are associated with the viral replication complexes. Further analysis of the localiza- tion of the identified host factors and the effect of virus infection on the ... See full document

14

Protein complex detection with semi-supervised learning in protein interaction networks

Protein complex detection with semi-supervised learning in protein interaction networks

... However, protein complexes are likely to overlap and the interaction data are very ...meaningful protein complex ...macromolecular complexes involving two or more proteins to perform ... See full document

9

Unveiling Disease-Protein Associations by Navigating a Structural Alphabet-Encoded Protein Network  

					                Tung et al.

Unveiling Disease-Protein Associations by Navigating a Structural Alphabet-Encoded Protein Network Tung et al.

... molecular networks are, however, inevitably limited by the assembled interactome network in terms of data quality, completeness and the biological significance of the interactions among ...using protein ... See full document

19

Original Article Exploring genes of rectal cancer based on protein interaction network

Original Article Exploring genes of rectal cancer based on protein interaction network

... a protein-protein interaction network of rectal cancer which is based on genetic genes, and then predicted biological pathways underlying the molecular complexes in the ...downloaded ... See full document

18

Identification of Candidate Genes related to Bovine Marbling using Protein-Protein Interaction Networks

Identification of Candidate Genes related to Bovine Marbling using Protein-Protein Interaction Networks

... gene networks or biological ...the identification of candidate genes related to complex diseases or traits at the system ...by protein-protein interaction (PPI) from the Human ... See full document

11

Filtering Gene Ontology semantic similarity for identifying protein complexes in large protein interaction networks

Filtering Gene Ontology semantic similarity for identifying protein complexes in large protein interaction networks

... length from the root node to x passing through its ...specificity from its ancestor a can be measured by the path length from a to ...paths from one node to another in DAGs, we define dis- ... See full document

10

Revealing Alzheimer’s disease genes spectrum in the whole-genome by machine learning

Revealing Alzheimer’s disease genes spectrum in the whole-genome by machine learning

... selected from the literature published before 2015, we also checked the predicted AD candidate gene set by scanning papers published post-2014 to verify the accuracy of our prediction (described in Table ... See full document

8

iOPTICS-GSO for identifying protein complexes from dynamic PPI networks

iOPTICS-GSO for identifying protein complexes from dynamic PPI networks

... the complexes identified by our algorithm, we calculated the p-value of the identified protein complexes on Biological Process ontologies based on four datasets by using the tool SGD ’ s GO: ... See full document

12

A model for collaboration networks giving rise to a power law distribution with exponential cutoff

A model for collaboration networks giving rise to a power law distribution with exponential cutoff

... in protein, e-mail, actor and collaboration net- works, and possibly in the web graph [MBSA02]; it is likely that exponential cutoffs also occur in other complex ...with networks such as collaboration and ... See full document

14

The Evolution of Gene-Specific Transcriptional Noise Is Driven by Selection at the Pathway Level

The Evolution of Gene-Specific Transcriptional Noise Is Driven by Selection at the Pathway Level

... fers from that in natural conditions under which natural selec- tion ...gene interaction are incomplete, and network-based mea- sures most likely have large error ... See full document

17

A fast approach to global alignment of protein protein interaction networks

A fast approach to global alignment of protein protein interaction networks

... results from two matching algorithms are reported [6], namely their implementation of the greedy and Hungarian algorithms – thus justifying the selection of iso greedy and iso hungarian names for the complete ... See full document

11

Modular organization in the reductive evolution of protein protein interaction networks

Modular organization in the reductive evolution of protein protein interaction networks

... throughput protein interaction maps of ...Buchnera interaction networks was based on the assumed low rate of protein interaction turnover [16] and the weak probability that new ... See full document

8

Accuracy improvement in protein complex prediction from protein interaction networks by refining cluster overlaps

Accuracy improvement in protein complex prediction from protein interaction networks by refining cluster overlaps

... First, we used varying parameter values of minCov and minCons between 0 and 1 to explore the effect of minCss on protein complex detection accuracy. Since the minimum consensus of 0 means taking the union of all ... See full document

12

Complex tree: the basic framework of protein protein interaction networks

Complex tree: the basic framework of protein protein interaction networks

... determined protein-protein interaction data was ut- ilized as the input ...the Protein-Protein Interactions with binary relations data from DIP, version DIP_20081014 ... See full document

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