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[PDF] Top 20 Integrin expression and function in osteoblasts

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Integrin expression and function in osteoblasts

Integrin expression and function in osteoblasts

... through integrin mediated signalling ...avp3 integrin is often associated with increased motility and invasiveness exhibited by malignant cells (Albelda et al, 1990) although the MG63 osteosarcoma cell-line ... See full document

190

Lack of effect of adenosine on the function of rodent osteoblasts and osteoclasts in vitro

Lack of effect of adenosine on the function of rodent osteoblasts and osteoclasts in vitro

... rodent osteoblasts or mouse osteoclasts. In rat bone marrow osteoblasts, 2-chloroadenosine exerted small effects on TNAP activity and bone formation, but only when added to cell cultures in extremely high ... See full document

29

Mobilization and homing of peripheral blood progenitors is related to reversible downregulation of alpha4 beta1 integrin expression and function

Mobilization and homing of peripheral blood progenitors is related to reversible downregulation of alpha4 beta1 integrin expression and function

... lates expression and function of the a 4 b 1 ...Increased expression of the a 4 b 1 integrin results in increased a 4-depen- dent adhesion of mobilized PB ...1 integrin is thought to be ... See full document

13

Sequential activation of the AKT pathway in human osteoblasts treated with Oscarvit: a bioactive product with positive effect both on skeletal pain and mineralization in osteoblasts

Sequential activation of the AKT pathway in human osteoblasts treated with Oscarvit: a bioactive product with positive effect both on skeletal pain and mineralization in osteoblasts

... the osteoblasts in growth medium supplemented with OSC there were qualitative differences when compared to the control cells growing in non-OSC-supplemented ...the osteoblasts after cultivation in ... See full document

9

The homeoprotein engrailed 1 has pleiotropic functions in calvarial intramembranous bone formation and remodeling

The homeoprotein engrailed 1 has pleiotropic functions in calvarial intramembranous bone formation and remodeling

... endosteal osteoblasts of wild-type calvarial bone, is severely impeded in En1 mutants ...mature osteoblasts in bone is not entirely clear; however, it correlates with previous studies ascribing inductive ... See full document

12

PET Imaging of Integrin αVβ3 Expression

PET Imaging of Integrin αVβ3 Expression

... of integrin expression is expected in the near fu- ...of integrin expression for patient se- lection and monitoring in the context of antiangio- genic or combined cytotoxic / antiangiogenic ... See full document

10

Rolipram, a Phosphodiesterase 4 Inhibitor, Stimulates Inducible cAMP Early Repressor Expression in Osteoblasts

Rolipram, a Phosphodiesterase 4 Inhibitor, Stimulates Inducible cAMP Early Repressor Expression in Osteoblasts

... mRNA expression was shown to require the de novo protein synthesis in osteoblasts ...enhanced expression of TRANCE by the activation of PKA would be determined by a complex balance of activation by ... See full document

6

ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function

ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function

... purified integrin recep- tors enhances receptor binding to collagen I, confirming a critical role for sialylation in regulating integrin ...1 integrin is integral to multicellular spheroid formation ... See full document

8

Integrin function and regulation in development

Integrin function and regulation in development

... Another interesting change in integrin expression during muscle development concerns the β1 subunit. By performing a PCR screening of the β1 mRNA in different tissues, we and others have identified a β1 ... See full document

7

Alterated integrin expression in lichen planopilaris

Alterated integrin expression in lichen planopilaris

... the expression of integrins and basement membrane (BM) components of the hair folli- cle in active LPP lesions and in healthy ...subjects. Integrin α 6 β 4 , a component of hemidesomsomes, is normally con- ... See full document

5

The adaptor protein Disabled-2: new insights into platelet biology and integrin signaling

The adaptor protein Disabled-2: new insights into platelet biology and integrin signaling

... species-specific expression of Dab2 isoforms are not yet ...Knock-in expression of p59-Dab2 only partially compromises the absence of Dab2 in the Dab2-knockout mice ...creased expression of p82-Dab2 ... See full document

7

Activin B induces human endometrial cancer cell adhesion, migration and invasion by up-regulating integrin β3 via SMAD2/3 signaling

Activin B induces human endometrial cancer cell adhesion, migration and invasion by up-regulating integrin β3 via SMAD2/3 signaling

... up-regulates integrin β3 mRNA and protein levels without altering the expression of integrin ...αv. Integrin β3 forms only two α-β heterodimers, αvβ3 and αIIbβ3, both of which are receptors ... See full document

15

Bcr/Abl expression stimulates integrin function in hematopoietic cell lines

Bcr/Abl expression stimulates integrin function in hematopoietic cell lines

... Bcr/Abl expression on the functions of two nonleukemic, IL-3–dependent, murine cell lines, 32D and BaF/3, derived from normal bone marrow cul- tures (29, ...Bcr/Abl expression similarly increased the ... See full document

9

Expression, topography, and function of integrin receptors are severely altered in keratinocytes from involved and uninvolved psoriatic skin

Expression, topography, and function of integrin receptors are severely altered in keratinocytes from involved and uninvolved psoriatic skin

... by integrin receptors that are segregated to discrete membrane ...the expression and function of integrins in psoriatic keratinocytes were examined, both in vivo and in ...the integrin ... See full document

14

A novel leukocyte adhesion deficiency caused by expressed but nonfunctional β2 integrins Mac 1 and LFA 1

A novel leukocyte adhesion deficiency caused by expressed but nonfunctional β2 integrins Mac 1 and LFA 1

... diminished expression of b2(CD18) ...lymphocyte function– associated molecule (LFA)-1 and Mac-1 at 40%–60% of normal ...of expression should be adequate for normal integrin function, ... See full document

11

Loss of beta1 integrin function results in upregulation of connexin expression in embryonic stem cell derived cardiomyocytes

Loss of beta1 integrin function results in upregulation of connexin expression in embryonic stem cell derived cardiomyocytes

... 1 integrin function correlated with up-regulated expres- sion of genes encoding gap junctional proteins in ES-derived cardiac cells; and this was paralleled by increased abundance of cardiac clusters ... See full document

9

Role of Integrin-linked kinase in epidermal integrity and barrier function

Role of Integrin-linked kinase in epidermal integrity and barrier function

... animals, expression of Cre recombinase under the control of the keratin-14 promoter results in excision of mTomato-encoding sequences, with the simultaneous induction of GFP ... See full document

235

Slowdown promotes muscle integrity by modulating integrin mediated adhesion at the myotendinous junction

Slowdown promotes muscle integrity by modulating integrin mediated adhesion at the myotendinous junction

... muscle-specific integrin receptors and their ligand ...specific integrin, we compared the viability of slow homozygous mutant female flies to that of slow mutant females that lack, in addition, one allele ... See full document

10

Upregulated expression and function of integrin adhesive receptors in systemic lupus erythematosus patients with vasculitis

Upregulated expression and function of integrin adhesive receptors in systemic lupus erythematosus patients with vasculitis

... of integrin adhesive receptors has been implicated in various pathological ...examined expression and function of integrin adhesive receptors on peripheral blood lymphocytes from patients with ... See full document

10

Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions

Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions

... recycling vesicles. These morphological characteristics putatively define the Vps3- and Vps8-positive vesicles as recycling vesicles. To determine whether the Vps3- and Vps8-positive vesicles also contain CORVET core ... See full document

13

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