[PDF] Top 20 Localization of epitopes of herpes simplex virus type 1 glycoprotein D.

... One of these, group VII antibody, was shown to react with a type-common continuous epitope within residues 11 to 19 of the mature glycoprotein residues 36 to 44 of the predicted sequence[r] ... See full document

... 1 Localization of Discontinuous Epitopes of Herpes Simplex Virus Glycoprotein D: Use of a Nondenaturing "Native" Gel System of Polyacrylamide Gel Electrophoresis Coupled with Western Blo[r] ... See full document

... a herpes vaccine will need to induce responses against a num- ber of promiscuous epitopes that are recognized in the context of many different HLA ...T-cell epitopes that belong to these supertypes ... See full document

... of virus travel within epidermal or neuronal cells, that gE is involved in release of virus into synaptic spaces, and that gE is required for efficient transport of virus from one cell to another ... See full document

... Location of the gene for gF on the HSV-2 genome and the genes for gC 9, 14 and TK 17, 32 on the HSV-1 genome and a summary of the results obtained from screening AraTr viruses that conta[r] ... See full document

... Cysteine mutants of herpes simplex virus type 1 glycoprotein D exhibit temperature-sensitive properties in structure and function.. Glycoprotein D protects mice against lethal challenge [r] ... See full document

... the epitopes have previously been localized for the respective, purified anti-mgG-2 antibody samples ...a type-specific anti-mgG-2 MAb in the serotyping of 2,400 clin- ical HSV-2 ... See full document

... This virus, derived from HSV strain 17, encodes gD with green fluorescent protein (GFP) fused to its C terminus; it replicates normally in vitro and will be described ... See full document

... 102-108 0022-538X/84/010102-07$02.00/0 Copyright C 1984, American Society for Microbiology Localization and Synthesis of an Antigenic Determinant of Herpes Simplex Virus Glycoprotein D T[r] ... See full document

... Herpes simplex virus (HSV) is an alpha-herpesvirus with two subtypes, HSV type 1 (HSV-1) and HSV-2, which both establish latent infections with different or similar clinical ex- ... See full document

... spread, virus was detected in the N chamber only in the presence of Vero cells; no virus was detected from neurites ...no virus is detected from free neurites (13). In contrast, West Nile ... See full document

... of virus were added for 1 h at 37°C to 5- to 8-day-old confluent monolayers of MDCK cells, and then monolayers were washed and overlaid with ...of virus was introduced via a soft ...at 1, 3, ... See full document

... With these problems in mind, we examined the vaccine potential of a fully disabled herpes simplex virus type 1 mutant that is capable of only a single round of replication, since a virus[r] ... See full document

... Detection of gH and gL oligomers during entry of HSV-1. Previously we showed that we could demonstrate the presence of gH-gL complexes in the virion by increasing the sensitivity of our detection system (19). This ... See full document

... The 104-S antibody also weakly precipiated the 130,000-molecular-weight herpes simplex virus type 1 HSV-1 glycoprotein gC from both infected cell extracts and purified preparations obtai[r] ... See full document

... When we analyzed each of the mutants in a complementation assay for virus function 38, only two mutant proteins, Cys-2 and Cys-4, Glycoprotein D gD of herpes simplex virus HSV is a struc[r] ... See full document

... D isolated from infected extracts had the same tryptic methionine peptide profile as D isolated from the virion envelope.. Thus, processing of pD to D does not involve any major alterati[r] ... See full document

... recombinant virus construc- tion. The UL20/UL53(gK) double-null recombinant virus, ⌬gK/⌬UL20, was gen- erated essentially as described previously for the isolation of the UL20-null virus ⌬UL20/gKDIV5 ... See full document

... Herpes simplex virus type 1 (HSV-1) glycoprotein gC binds complement component C3b, and purified gC inhibits complement ...after 1 h of incubation with serum. In ... See full document

... Cloned fragments derived from ANG or KOS or constructed from both were transfected into cells with ANG BamHI-A/EcoRI-D and KOS DNA, and the progeny virus was tested by inoculation on rea[r] ... See full document