[PDF] Top 20 Mutations in the 5' end of the herpes simplex virus type 2 latency-associated transcript (LAT) promoter affect LAT expression in vivo but not the rate of spontaneous reactivation of genital herpes.
Has 10000 "Mutations in the 5' end of the herpes simplex virus type 2 latency-associated transcript (LAT) promoter affect LAT expression in vivo but not the rate of spontaneous reactivation of genital herpes." found on our website. Below are the top 20 most common "Mutations in the 5' end of the herpes simplex virus type 2 latency-associated transcript (LAT) promoter affect LAT expression in vivo but not the rate of spontaneous reactivation of genital herpes.".
Mutations in the 5' end of the herpes simplex virus type 2 latency-associated transcript (LAT) promoter affect LAT expression in vivo but not the rate of spontaneous reactivation of genital herpes.
... of LAT copies in latently infected guinea pig ...the LAT in each sample. About 1 ng of sample RNA in 5 m l was added to each ...4, 5 m l of competitor RNA was added in fourfold-increasing ... See full document
8
A 371-nucleotide region between the herpes simplex virus type 1 (HSV-1) LAT promoter and the 2-kilobase LAT is not essential for efficient spontaneous reactivation of latent HSV-1.
... The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) gene is essential for efficient spontaneous reactivation of HSV-1 from ... See full document
5
The spontaneous reactivation function of the herpes simplex virus type 1 LAT gene resides completely within the first 1.5 kilobases of the 8.3-kilobase primary transcript.
... The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) gene is essential for efficient spontaneous reactivation of HSV-1 from ... See full document
9
Latency-Associated Transcript (LAT) Exon 1 Controls Herpes Simplex Virus Species-Specific Phenotypes: Reactivation in the Guinea Pig Genital Model and Neuron Subtype-Specific Latent Expression of LAT
... Herpes simplex virus 1 (HSV-1) and HSV-2 cause similar acute infections but differ in their abilities to reactivate from trigeminal and lumbosacral dorsal root ...During latency, HSV-1 ... See full document
9
Tissue-Specific Splicing of the Herpes Simplex Virus Type 1 Latency-Associated Transcript (LAT) Intron in LAT Transgenic Mice
... the LAT have been previ- ously ...constitutive promoter (cytomegalovirus [CMV]) and was used to examine the effect of expression of the ...2.0-kb LAT intron on acute and latent HSV-1 ... See full document
10
The Latency-Associated Transcript Gene Enhances Establishment of Herpes Simplex Virus Type 1 Latency in Rabbits
... The latency-associated transcript (LAT) gene the only herpes simplex virus type 1 (HSV-1) gene abundantly transcribed during neuronal latency, is essential ... See full document
7
In vivo epinephrine reactivation of ocular herpes simplex virus type 1 in the rabbit is correlated to a 370-base-pair region located between the promoter and the 5' end of the 2.0 kilobase latency-associated transcript.
... FIG. 2. Southern blot analysis of DNA isolated from virus following in vivo reactivation or explant ...rescuant virus were explanted. The DNA from reactivated virus was isolated, ... See full document
5
Identification of Herpes Simplex Virus Type 1 Latency-Associated Transcript Sequences That both Inhibit Apoptosis and Enhance the Spontaneous Reactivation Phenotype
... The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) gene is essential for the high spontaneous and induced reactivation ... See full document
6
A Herpes Simplex Virus Type 1 Latency-Associated Transcript Mutant with Increased Virulence and Reduced Spontaneous Reactivation
... The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) gene is essential for efficient spontaneous reactivation of HSV-1 from ... See full document
10
Analysis of the promoter and cis-acting elements regulating expression of herpes simplex virus type 2 latency-associated transcripts.
... HSV-2 LAT genes are highly conserved (19, ...HSV-2 LAT promoter (2LATP) region identical to those found in the HSV-1 LAT promoter (1LATP) region, namely, the TATA box and ... See full document
8
The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency.
... Herpes simplex virus type 1 establishes latent infections in sensory ...During latency only one locus, the latency-associated transcript (LAT), is abundantly ... See full document
9
A Novel Herpes Simplex Virus Type 1 Transcript (AL-RNA) Antisense to the 5′ End of the Latency-Associated Transcript Produces a Protein in Infected Rabbits
... infection, herpes simplex virus type 1 (HSV-1) establishes a lifelong latent infection in sensory neurons of the trigeminal ...ganglia. Latency-associated transcript ... See full document
8
An avirulent ICP34.5 deletion mutant of herpes simplex virus type 1 is capable of in vivo spontaneous reactivation.
... maintain) latency with approximately 19 to 36% of the efficiency of the rescued virus, as judged by semiquantitative PCR analysis of viral ...this type of analysis (7, ...establish latency at ... See full document
9
Herpes Simplex Virus 2 Latency-Associated Transcript (LAT) Region Mutations Do Not Identify a Role for LAT-Associated MicroRNAs in Viral Reactivation in Guinea Pig Genital Models
... noncoding latency-associated transcript (LAT), which is transcribed from within the long repeats of the viral genome ...the LAT promoter is highly active during latency, ... See full document
12
Deacetylation of the Herpes Simplex Virus Type 1 Latency-Associated Transcript (LAT) Enhancer and a Decrease in LAT Abundance Precede an Increase in ICP0 Transcriptional Permissiveness at Early Times Postexplant
... Herpes simplex virus type 1 (HSV-1) is characterized by its ability to establish latency as an episome in neurons ...the latency-associated transcript (LAT), ... See full document
6
Detection of herpes simplex virus type 1 latency-associated transcript expression in trigeminal ganglia by in situ reverse transcriptase PCR.
... of LAT expression detected by ISH as a measure of the number of genome- containing cells underestimates the number of latent HSV genome-containing cells in a trigeminal ...detect LAT ... See full document
5
Physical characterization of the herpes simplex virus latency-associated transcript in neurons.
... 1194 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest RNA transfer Northern blot analysis was used to perform the physical characterization of the transcript expressed i[r] ... See full document
9
Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1.
... By using various fragments and deletion constructs, this promoter activity 3269 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest To identify promoter regions which contr[r] ... See full document
11
The region of the herpes simplex virus type 1 LAT gene that is colinear with the ICP34.5 gene is not involved in spontaneous reactivation.
... tivated virus recovered from the eyes of rabbits latently in- fected with the ...wild- type virus or mutant virus that had somehow reverted back to wild-type virus, Southern ... See full document
10
Evidence that the Herpes Simplex Virus Type 1 ICP0 Protein Does Not Initiate Reactivation from Latency In Vivo
... of latency, including the number of latently infected neu- rons and the number of viral genomes present in individual neurons, were ...vitro reactivation of ⌬ Tfi 22 h postexplant was indistinguishable from ... See full document
12
Related subjects