[PDF] Top 20 Original Article Genetic polymorphisms and phenotypic analysis of CYP2A6 in the Sherpa population
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Original Article Genetic polymorphisms and phenotypic analysis of CYP2A6 in the Sherpa population
... in CYP2A6 alleles and CYP2A6 activity have been studied in several ...of CYP2A6 allele frequency in the Sherpa populations, we systematically screened the whole CYP2A6 genes of 100 ... See full document
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Original Article Genetic polymorphisms of INSIG2 were associated with coronary artery disease in Uygur Chinese population in Xinjiang, China
... Weight and height were measured in a stan- dard method, and body mass index (BMI) was calculated. After 5 min of rest, blood pressure was measured three times within 10 min and the median value was used in the ... See full document
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Original Article Relationship between H19 genetic polymorphisms and the risk of unexplained recurrent miscarriage in a Chinese population: a population-based study
... H19 genetic polymorphisms (rs2067051, rs2251375, rs217727 and rs4929984) and the risk of unexplained recurrent miscarriage (RM) in a Chinese popu- ...detect genetic polymorphisms of rs2067051, ... See full document
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Original Article Genetic polymorphisms of ADIPOQ and osteonecrosis of the femoral head risk in Chinese population
... study population was consis- tent with the standard of the selection and pos- sessed the representativeness of ...association analysis between ADIPOQ polymorphisms with ONFH susceptibil- ity, the ... See full document
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Original Article Association between MLL3 genetic polymorphisms and development of laryngeal cancer in a Chinese population
... sequence analysis of well-annotat- ed human protein coding genes or consensus coding sequences in colorectal cancers and breast cancers indicated that mutations of MLL3 were frequent in these cancers [26, ... See full document
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Original Article Genetic polymorphisms of pharmacogenomic VIP variants in the lhoba population of southwest China
... global genetic variation distribution for these specific ...the genetic structure analysis of 12 ...Lhoba population differed from those of the ASW, CEU, CHB, CHD, GIH, JPT, LWK, MEX, MKK, ... See full document
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Original Article Genetic association of cyclooxygenase-2 gene polymorphisms with Parkinson’s disease susceptibility in Chinese Han population
... the genetic association of cyclooxygenase-2 (COX2) gene promoter region polymorphisms with Parkinson’s disease (PD) susceptibility in Chinese Han ...gene polymorphisms was conducted by polymerase ... See full document
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Original Article Genetic polymorphisms in COL18A1 influence the development of osteosarcoma
... regression analysis, we found that individuals with the NN genotype of COL18A1 D104N were significantly associated with an increased risk of osteosarcoma when compared with the DD genotype ... See full document
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Original Article Association between vitamin D receptor genetic polymorphisms and haplotypes and risk of lumbar degenerative disc disease in a Chinese population
... Abstract: Degenerative disc disease is a continuous degeneration process of intervertebral discs. We performed a case-control study to investigate the association between 16 common SNPs of VDR and degenerative disc ... See full document
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Original Article Genetic analysis of drug-metabolizing enzyme CYP3A5 polymorphisms in Tibetans in China
... We screened the CYP3A5 genetic polymor- phisms of Tibetan population by DNA direct sequencing. Genomic DNA was extracted from whole peripheral blood using a GoldMag-Mini Whole Blood Genomic DNA Purification ... See full document
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Original Article Association of SELP genetic polymorphisms and additional gene-smoking interaction on cardiovascular disease in Chinese Han population
... (SELP) genetic polymorphisms and its interaction with smok- ing on cardiovascular disease (CVD) risk based on Chinese ...regression analysis showed that CVD risk was significantly lower in carriers ... See full document
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Original Article Association analysis of ALOX5 gene polymorphisms with stroke risk: a case-control study in a Chinese Han population
... world. Genetic factors have been implicated in stroke risk but few have been ...gene polymorphisms and stroke risk in a Chinese Han ...nucleotide polymorphisms (SNPs) of the ALOX5 gene to test the ... See full document
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Original Article Genetic polymorphisms of C-reactive protein increase susceptibility to HBV-related hepatocellular carcinoma in a Guangxi male population
... by genetic variation in CRP ...CRP polymorphisms and HBV-related HCC risk in a Chinese male ...this population. In haplotype analysis between HBV patients with HCC and HBV patients without ... See full document
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Original Article The genetic analysis of β2 adrenergic receptor gene polymorphisms and preterm birth risk in a Chinese population
... exists genetic polymor- phism, especially SNPs and they affect the bio- logical characteristics of acceptor through modifying the structure of ADRB2 gene or expression level of ADRB2 protein ... See full document
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Original Article Genetic polymorphisms and the susceptibility to brain arteriovenous malformation
... mixed population under the dormant model (AA+AG vs ...ALK1 polymorphisms and BAVM risk in 503 Dutch ...meta- analysis collected 410 BAVM patients and 684 healthy controls showed that ALK1 rs2071219 ... See full document
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Original Article Association of genetic polymorphisms with pulmonary tuberculosis in a Chinese Tibetan population: a case-control study
... We selected 20 SNPs from GWA studies that were previously reported to be associated with pulmonary tuberculosis. Minor allele frequen- cies of all SNPs were > 5%, in the HapMap of the Chinese Han Beijing (CHB) ... See full document
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Original Article Polymorphisms and phenotypic analysis of cytochrome P450 3A4 in the Uygur population in northwest China
... the analysis of novel genetic variants in the promoter region, -747C > G, -667C > T, and -392A > G altered the transcription binding site in promoter ... See full document
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Original Article Genetic distribution and association analysis of DRD2 gene polymorphisms with major depressive disorder in the Chinese Han population
... A total of 338 unrelated adult Chinese, includ- ing 224 healthy volunteers and 114 patients with MDD were recruited in this study. All of them were biologically unrelated individuals of Chinese Han origin living in ... See full document
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Original Article Genetic polymorphisms of the drug-metabolizing enzyme cytochrome P450 2A6 in a Tibetan Chinese population
... We used the online tools SIFT (http://sift.bii.a- star.edu.sg/) and PolyPhen-2 (http://genetics. bwh.harvard.edu/pph2/) to predict protein fun- ction of non-synonymous SNPs in CYP2A6 cod- ing regions. Each variant ... See full document
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Original Article Genetic polymorphisms and phenotypic analysis of drug-metabolizing enzyme CYP2C19 in a Li Chinese population
... Genetic polymorphisms in CYP2C19 are highly involving in the metabolism of many clinically prescribed drugs and may give rise to impor- tant inter-individual and inter-ethnic differenc- es in patient ... See full document
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