[PDF] Top 20 Rolling circle DNA replication by extracts of herpes simplex virus type 1-infected human cells.

... of herpes simplex virus type 1 (HSV-1) circularizes upon the infection of susceptible cells and replicates predominantly by a rolling circle mechanism ... See full document

... Herpes simplex virus type 1 (HSV-1) is a neurotropic her- pesvirus which causes a variety of infections in ...lytic replication of the virus after reactivation from ... See full document

... of herpes simplex virus type 1 (HSV-1) (nuc mutations) induce almost wild-type levels of viral DNA; however, mutant viral yields are ...to 1% of ... See full document

... The herpes simplex virus type 1 (HSV-1) origin of DNA replication, oriS, contains three binding sites for the viral origin binding protein (OBP) flanked by ... See full document

... with herpes simplex virus type 1 (HSV-1) results in the rapid elimination of mitochondrial DNA (mtDNA) from host ...viral replication or the biology of HSV-1 ... See full document

... of infected DC was proportional to the input multiplicity, but it never exceeded 80% of total DC population, even at 10 PFU/cell, indicating that a portion of DC were refractory to the ...of cells remained ... See full document

... replicating DNA from cells infected with the AN-1 ...during replication to prevent the formation of aberrant ...late replication may be initiated by strand invasion of 39 ends, ... See full document

... 2 cells (Stratagene, La Jolla, ...with 1 ␮g of plasmid using Lipofectamine (Gib- coBRL, Carlsbad, ...tion, cells were infected with KOS at an MOI of 5 in the presence or absence of 400 ␮g of ... See full document

... early human cytomegalovirus infection, an- other herpesvirus, appears to favor infectious viral production (18), but this was not the case for measles virus ...HSV-1–infected cells were ... See full document

... HSV-1 replication in human macrophage cell ...for replication of the HSV-1 DNA ge- ...cycling cells but is unphosphorylated at this residue in noncycling myeloid ... See full document

... the replication complex. These results suggest that the DNA replication in this assay is not fully processive and that substantial displacement of the rep- lication complex is occurring at specific ... See full document

... the replication fork located between the recom- bining a inverted ...two replication forks are now chasing each other on the circular genome, with the production of concatemers, as in a rolling ...of ... See full document

... on human cancer epithelial cells ...HEL cells using different shRNAs ...Vero cells. We found that in CD63 knockdown HEL cells the wild-type virus yields were ⬎ 20-fold ... See full document

... lular DNA replication lends indirect support to the concept that UL29 may be bound to single-stranded ...single-stranded DNA, thereby forming prereplicative ...identified. Cells trans- fected ... See full document

... one type of animal cell death in which cells die by an active cellular process under the genetic control of the cells (“death program”) ...in infected cells (5, 23, 25), it has not been ... See full document

... MeWO cells infected in parallel either with WT virus in the presence or absence of drugs or with ...viral DNA synthesis was blocked genetically or ... See full document

... in infected BJ cells raised the pos- sibility that endogenous IFN-␤ was synthesized, presumably following the pathway in which activated IRF-3, in conjunction with other cellular factors, forms the ... See full document

... In the present study, we show that topoisomerase II activity persists in HSV-1-infected cells and that both forms are present throughout the infection; however, only p170 topoisomerase I[r] ... See full document

... of human AP endonuclease (HAP-1), suggesting that HAP-1 promotes AP site release by UNG and couples the steps of base excision repair ...abasic DNA in vitro (13, 42), the previously observed ... See full document

... herpesvirus type 1 (EHV-1), bovine herpesvirus type 1 (BHV-1), varicella-zoster virus (VZV), HSV-1, and Marek’s disease virus (MDV) were aligned using the ... See full document