[PDF] Top 20 Subgenomic Negative-Strand RNA Function during Mouse Hepatitis Virus Infection
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Subgenomic Negative-Strand RNA Function during Mouse Hepatitis Virus Infection
... minus strand to detach and reinitiate transcription (in cis or in trans) at the 5⬘ end of the ...all subgenomic negative strands originate from the genomic RNA directly, rather than from ... See full document
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Polypyrimidine Tract-Binding Protein Binds to the Complementary Strand of the Mouse Hepatitis Virus 3′ Untranslated Region, Thereby Altering RNA Conformation
... Mouse hepatitis virus (MHV) RNA transcription is regulated mainly by the leader and intergenic (IG) ...for subgenomic mRNA transcription; deletion of nucleotides (nt) 270 to 305 from ... See full document
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The Leader RNA of Coronavirus Mouse Hepatitis Virus Contains an Enhancer-Like Element for Subgenomic mRNA Transcription
... Mouse hepatitis virus (MHV) is the prototype of Murine coronavirus, a member of the family ...single-stranded RNA genome 31 kb long, which encodes seven to eight genes (16, 18, ...Upon ... See full document
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Interactions between the cytoplasmic proteins and the intergenic (promoter) sequence of mouse hepatitis virus RNA: correlation with the amounts of subgenomic mRNA transcribed.
... the negative-strand IG sequence of MHV ...and negative strands of the 5 9 UTR of MHV RNA (5), which are the sequence involved in the regulation of RNA synthesis ...MHV RNA also ... See full document
8
Mouse Hepatitis Virus Stem-Loop 4 Functions as a Spacer Element Required To Drive Subgenomic RNA Synthesis
... directing subgenomic RNA ...genomic RNA, as described in the negative-strand discon- tinuous transcription model defined by Zuniga et ...MHV RNA leader TRS, and heterogeneous ... See full document
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Identification of the Intragenomic Promoter Controlling Hepatitis E Virus Subgenomic RNA Transcription
... SG RNA synthesis were truly dependent on this cis-acting element, then mutations in this region abrogating this function would severely impair particle pro- duction and release, as the SG RNA is the ... See full document
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Hepatitis C Virus Subgenomic Replicon Requires an Active NS3 RNA Helicase
... cellular RNA was extracted from ...cellular RNA using SuperScript II RNase H- reverse transcriptase (RT) (Invitrogen) in the presence of 100 nM of one of two primers complementary to the HCV 5 ⬘ ... See full document
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Specific Interaction of Hepatitis C Virus Protease/Helicase NS3 with the 3′-Terminal Sequences of Viral Positive- and Negative-Strand RNA
... C virus (HCV) is the primary causative agent of parenterally transmitted non-A, non-B hepatitis and affects a significant part of the world’s ...HCV infection fre- quently leads to chronic ... See full document
14
Function of a 5'-end genomic RNA mutation that evolves during persistent mouse hepatitis virus infection in vitro.
... measured during MHV persistence through 119 days postin- ...positive-stranded RNA viruses, including trans- missible gastroenteritis virus (27, 40, ...leader RNA evolved at much lower rates ... See full document
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Coronavirus transcription: subgenomic mouse hepatitis virus replicative intermediates function in RNA synthesis.
... Because only genome-length negative-strand templates were found in mouse hepatitis virus MHV-infected cells and in replicative intermediates RIs obtained from MHV-infected cells and beca[r] ... See full document
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Search for Hepatitis C Virus Negative-Strand RNA Sequences and Analysis of Viral Sequences in the Central Nervous System: Evidence of Replication
... visna virus infection ...HIV-1 infection (28, ...HCV negative-strand RNA is rarely detected in PBMC from normal subjects (15, 24), it is commonly found in HIV-coinfected patients ... See full document
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Lack of detection of negative-strand hepatitis C virus RNA in peripheral blood mononuclear cells and other extrahepatic tissues by the highly strand-specific rTth reverse transcriptase PCR.
... of negative-strand HCV RNA in PBMC from humans infected with ...PBMC RNA was purified, diluted in normal cell RNA, and subjected to strand-specific RT-PCR for ... See full document
5
Identification of the Hepatitis C Virus RNA Replication Complex in Huh-7 Cells Harboring Subgenomic Replicons
... plus-strand RNA viruses where single pro- teins expressed alone or in the context of the entire open reading frame induced membrane alterations very similar to membrane changes found during natural ... See full document
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Secondary Structure of the 3′ Terminus of Hepatitis C Virus Minus-Strand RNA
... (⫺) strand RNA is the strict anti- sense sequence of the (⫹) strand ...(⫺) strand RNA, SL-AI, is indeed the mirror image of domain in the ...(⫺) strand RNA as stressed by ... See full document
11
Common Mechanism for RNA Encapsidation by Negative-Strand RNA Viruses
... without RNA and an ...own RNA encapsidation cavity ...the RNA are sequestered in the nucleocapsid, as observed for the RVFV ...the RNA cavity to interact with the neighboring N subunit ...kept ... See full document
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Specific Sindbis virus-coded function for minus-strand RNA synthesis.
... In cultures infected with tsll of complementation group B, the synthesis of viral minusstrand RNA ceased, whereas the synthesis of 42S and 26S plus-strand RNAs continued for at least 5 h[r] ... See full document
11
Specific detection of hepatitis C virus minus strand RNA in hematopoietic cells
... of negative (or positive) strand RNA to tightly match the vari- ous HCV genotype sequences so far described, thus allowing the unambiguous amplification of distinct HCV genotypes (In- chauspé, ... See full document
8
Evolution of mouse hepatitis virus: detection and characterization of spike deletion variants during persistent infection.
... coronavirus mouse hepatitis virus JHM (MHV- JHM) causes acute and chronic neurological disease upon infection of the central nervous system (CNS) of susceptible rodents and has been ... See full document
11
Poly(A) at the 3′ End of Positive-Strand RNA and VPg-Linked Poly(U) at the 5′ End of Negative-Strand RNA Are Reciprocal Templates during Replication of Poliovirus RNA
... positive-strand RNA viruses ...their RNA genomes (16, 25), yet the mechanisms by which 3 ⬘ poly(A) sequences are derived during viral replication are un- ...Picornavirus RNA genomes, ... See full document
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Synthesis of subgenomic mRNA's of mouse hepatitis virus is initiated independently: evidence from UV transcription mapping.
... VAN DER ZEIJST* Institute of Virology, Veterinary Faculty, State University, 3508 TD Utrecht, The Netherlands The target sizes of the templates for the synthesis of the genome-sized RNA [r] ... See full document
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