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[PDF] Top 20 Visualizing Allele Specific Expression In Single Cells

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Visualizing Allele Specific Expression In Single Cells

Visualizing Allele Specific Expression In Single Cells

... detecting single-nucleotide polymorphisms (SNPs) at the single-cell and single-molecule level using RNA fluorescent in situ hybridization ...mutant cells have di↵erent imprinting behavior that ... See full document

134

Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene

Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene

... strict allele-specific association of DNA methylation and chromatin markers at imprinted genes, histone modifications at the nonimprinted, monoalleli- cally expressed IGF2BP1 gene do not predict the active ... See full document

16

Discovering Single Nucleotide Polymorphisms Regulating Human Gene Expression Using Allele Specific Expression from RNA-seq Data

Discovering Single Nucleotide Polymorphisms Regulating Human Gene Expression Using Allele Specific Expression from RNA-seq Data

... relative expression of the two copies of the gene (Figure ...” allele at the regulatory SNP site causes higher expression of the gene relative to the “T” ... See full document

11

An in vitro ES cell imprinting model shows that imprinted expression of
the Igf2r gene arises from an allele specific expression bias

An in vitro ES cell imprinting model shows that imprinted expression of the Igf2r gene arises from an allele specific expression bias

... In allele-specific QPCR assays, the maternal to paternal Igf2r ratio did not exceed 10:1 in differentiated cells, even though the calculated specificity for the QPCR SNP assay was at least ... See full document

12

MBASED: allele specific expression detection in cancer tissues and cell lines

MBASED: allele specific expression detection in cancer tissues and cell lines

... a single sample of oral cancer ...The single exception among the tumor tissues came from NSCLC individual 2, which exhibited ASE in 17% of tested genes (similar to other cancer tissue samples; Figure 4B), ... See full document

21

Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states

Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states

... ESC-PGA cells is different from the female oocyte donor: B6D2F1 ESC-PGA lines are homozygous proximal to the cen- tromere, while they are heterozygous at distal regions for most chromosomes ...for allele- ... See full document

21

Allele-specific expression in the human heart and its application to postoperative atrial fibrillation and myocardial ischemia

Allele-specific expression in the human heart and its application to postoperative atrial fibrillation and myocardial ischemia

... cardiac cells and is an interesting target for further ...that expression differences affecting this pathway are in- volved in the immediate response to ischemia and they serve as interesting targets for ... See full document

12

Allele specific binding of ZFP57 in the epigenetic regulation of imprinted and non imprinted monoallelic expression

Allele specific binding of ZFP57 in the epigenetic regulation of imprinted and non imprinted monoallelic expression

... the expression of 19 genes adjacent to these sites. Allele-specific expression was investigated using four different reciprocal hybrid ES cell lines and neural stem (NS) cell progenitors ... See full document

18

Allele-specific detection of single mRNA molecules in situ

Allele-specific detection of single mRNA molecules in situ

... (13 allele-specific probes), the spots from cells expressing only Castaneus transcripts form a cloud along the Cy5 axis, while dots from cells expressing only 129 transcripts form a cloud ... See full document

11

Notch induced T cell development requires phosphoinositide dependent kinase 1

Notch induced T cell development requires phosphoinositide dependent kinase 1

... flDneo allele had occurred in T-PDK L155E/" DPs (Supplementary Figure ...with specific phosphorylated S6 ...that expression of a single WT PDK1 allele can support activation of S6K1 ... See full document

10

SCALE: modeling allele specific gene expression by single cell RNA sequencing

SCALE: modeling allele specific gene expression by single cell RNA sequencing

... whose allele-specific bursting is in a coordinated fashion than those for which it is in a repulsed ...of cells during mouse embryonic develop- ment, as we combine the early-, mid-, and ... See full document

15

Advances in the identification and analysis of allele-specific expression

Advances in the identification and analysis of allele-specific expression

... Allele-specific expression (ASE) is essential for normal development and many cellular processes but, if impaired, can result in ...germ cells, which are haploid), resulting in multiple ... See full document

5

Allele-specific expression of mutated in colorectal cancer (MCC) gene and alternative susceptibility to colorectal cancer in schizophrenia

Allele-specific expression of mutated in colorectal cancer (MCC) gene and alternative susceptibility to colorectal cancer in schizophrenia

... and rs2227947 were in the range of 0.52–3.79, 0.5–3.33, 0.57–2.42, and 0.48–3.24 respectively (Fig. 1), and that of the MCC gene ranged from 0.52 to 3.79 (Fig. 2). Moreover, we were able to ensure the accuracy and ... See full document

15

Allele-specific disparity in breast cancer

Allele-specific disparity in breast cancer

... of allele-specific chromoso- mal aberrations and loss of heterozygocity (LOH) status ...a single- SNP, cytogenic region as well as in gene lists and at the pathway ... See full document

13

Protein-DNA Interactions and Protein-Protein Interactions Affect Transcriptional Regulation of Wood Cell Wall Biosynthesis in Populus trichocarpa

Protein-DNA Interactions and Protein-Protein Interactions Affect Transcriptional Regulation of Wood Cell Wall Biosynthesis in Populus trichocarpa

... assays, specific antibodies against native TF proteins is essential, but the quality of antibodies for IP are difficult to generate for many TFs in network- scale experiments (Mourik et ...cultured cells ... See full document

208

Visualizing Herpesvirus Procapsids in Living Cells

Visualizing Herpesvirus Procapsids in Living Cells

... fected cells, and these structures failed to acquire red ...in visualizing procapsids in living ...not specific to procapsids but rather labels all capsid ... See full document

11

Engineering heat tolerance in potato by temperature dependent expression of a specific allele of HEAT SHOCK COGNATE 70

Engineering heat tolerance in potato by temperature dependent expression of a specific allele of HEAT SHOCK COGNATE 70

... alleles of the presumed HSc70 gene in this study are more closely related to other HSc70 genes in Arabidopsis and tomato than to HSP70 sequences (Figure S5). Nevertheless, the A2 allele identified here is clearly ... See full document

11

EXPRESSION AND STABILITY OF THE MARBLED ALLELE IN MAIZE

EXPRESSION AND STABILITY OF THE MARBLED ALLELE IN MAIZE

... Since preliminary observations had suggested that the frequency of self-colored mutants might be greater in dark than in light marbled lines, three very light families (1-5 per[r] ... See full document

7

ALLELE SPECIFIC DETERMINANTS OF HOMOTHALLISM IN SACCHAROMYCES LACTIS

ALLELE SPECIFIC DETERMINANTS OF HOMOTHALLISM IN SACCHAROMYCES LACTIS

... ‘To test the second alternative, that the observed instability in mating type was due to some quality unique to the newly derived a cell, the homothallic behavior of segregants de[r] ... See full document

14

PCR-based assays for validation of single nucleotide polymorphism markers in rice and mungbean

PCR-based assays for validation of single nucleotide polymorphism markers in rice and mungbean

... In a previous work, a set of 26 local Vietnamese Oryza sativa spp. japonica and spp. indica rice cultivars held in the National Crop Genebank of the Plant Resources Center of the Vietnam Academy of Agricultural Sciences, ... See full document

13

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