protein-protein interaction (PPI)
Fitting a geometric graph to a protein-protein interaction network
... for protein–protein interaction (PPI) networks is a fundamental ...PPI interaction data and embeds proteins into a low-dimensional Euclidean space, under the premise that connectivity ...
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A New Algorithm for Protein-Protein Interaction Prediction
... The proteins are some of the most important molecules in cells ([34]). They carry out most of the cellular processes. Quite often, they keep the cells functioning by interacting with other proteins in stable or transient ...
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Detecting Protein Complexes by an Improved Affinity Propagation Algorithm in Protein-Protein Interaction Networks
... of protein complexes in protein-protein interaction (PPI) networks is important in understanding cellular ...discover protein complexes with high precision by compared with the AP, MCL, ...
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HMNPPID—human malignant neoplasm protein–protein interaction database
... plasm Protein–Protein Interaction Database (HMNPPID) was constructed, whose data was extracted by an auto- matic PPI extraction tool, named PPIExtractor [27], from a large number of PubMed 15 ...
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RETRACTED ARTICLE: Establishing an osteosarcoma associated protein-protein interaction network to explore the pathogenesis of osteosarcoma
... Compared to the control samples, the expressions of 42 and 341 genes were altered in non-metastatic OS were analyzed in duplicate), and 11 samples for metastatic patients (10 of which were analyzed in duplicate). ...
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Complex tree: the basic framework of protein protein interaction networks
... determined protein-protein interaction data was ut- ilized as the input ...the Protein-Protein Interactions with binary relations data from DIP, version DIP_20081014 ...
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Modular organization in the reductive evolution of protein protein interaction networks
... throughput protein interaction maps of ...Buchnera interaction networks was based on the assumed low rate of protein interaction turnover [16] and the weak probability that new ...
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Construction and analysis of protein-protein interaction network associated with human sperm-egg interaction
... identify protein-protein interaction between human sperm and egg (Evans, ...of protein complexes, many efforts have failed to comprehensively elucidate the fusion mechanism and the molecular ...
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High throughput protein-protein interaction data: clues for the architecture of protein complexes
... TATA-binding protein and other transcrip- tion factors [34,35] It has three distinct functional modules [26,28,35,36] along with other associated pro- ...put protein-protein interaction ...
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Characterization of Protein Interfaces to Infer Protein-Protein Interaction
... of interaction of two key macromolecular species is one of the major problems in structural and molecular ...of protein – protein interactions depend upon knowledge of both the three dimensional ...
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Modularity detection in protein protein interaction networks
... Background: Many recent studies have investigated modularity in biological networks, and its role in functional and structural characterization of constituent biomolecules. A technique that has shown considerable promise ...
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Protein-protein interaction databases: keeping up with growing interactomes
... known protein – protein interactions has increased ...store protein – protein interaction data. Protein – protein interactions have been retrieved from six major ...
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DIFFERENT APPROACHES FOR STUDYING PROTEIN PROTEIN INTERACTION AND ANALYSIS
... in protein and protein networking databases gives the first insight to study such macromolecular interactions paving the way for their in-vitro and in-vivo ...the protein-protein ...
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Algorithmic approaches to protein-protein interaction site prediction
... on protein surfaces mediate virtually all biological activities, and their identification holds promise for disease treatment and drug ...modern protein-protein interaction site (PPIS) ...
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A fast approach to global alignment of protein protein interaction networks
... From an evolutionary standpoint, one can argue that the set of orthologous genes in the pair of species could have diverged and either gained or lost specific functions. These functional adaptations are reflected in the ...
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Protein-Protein Interaction Network Alignment
... about protein complexes, pathways and modules are also very important in PPI network ...in protein functions research, they are also a vital standard to measure network alignment ...annotated protein ...
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Learning Protein–Protein Interaction Extraction using Distant Supervision
... PPI extraction is usually tackled by classifying the n 2 undirected protein mention pairs within a sentence, where n is the number of protein men- tions in the sentence. Classification of such pairs is ...
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Training host pathogen protein–protein interaction predictors
... of protein-protein interactions (PPIs) plays a vital role in molecular ...(Host-Pathogen Interaction Predictor) that can predict interactions between human and viral ...
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GIDMP: Good protein-protein interaction data metamining practice
... on protein-protein interactions (PPI), while ConsensusPathDB and PathwayCommons strive to create biological pathways containing ...the interaction being available in one of the source databases mined ...
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A Meta-Heuristic Approach to Predict Protein-Protein Interaction Network
... functional organization of the cell. Understanding biological processes thus relies on a comprehensive knowledge of different types of protein–protein interactions (PPIs) and interaction mechanisms. ...
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