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Quantitative trait locus mapping

Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22

Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22

... gene locus in our study may be due to population differences or the fact that the subjects in our population did not, in general, exhibit elevated blood pressure and were not primarily ascertained from fami- lies ...

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Consequences of Recombination Rate Variation on Quantitative Trait Locus Mapping Studies: Simulations Based on the Drosophila melanogaster Genome

Consequences of Recombination Rate Variation on Quantitative Trait Locus Mapping Studies: Simulations Based on the Drosophila melanogaster Genome

... backcross mapping studies if 1000 progeny were ...interval mapping (Zeng 1994) procedure on the simulated results with a window size of 10 cM and using up to five background ...

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Selective Genotyping With Epistasis Can Be Utilized for a Major Quantitative Trait Locus Mapping in Hypertension in Rats

Selective Genotyping With Epistasis Can Be Utilized for a Major Quantitative Trait Locus Mapping in Hypertension in Rats

... this locus, we found qualitative borderline of this study, we attempted to backcross the former DRY significance in cosegregation with BP phenotype, that Tanase used 30 years ago to SHR (Tanase ...

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Rank-Based Statistical Methodologies for Quantitative Trait Locus Mapping

Rank-Based Statistical Methodologies for Quantitative Trait Locus Mapping

... nonnormal quantitative traits with focus on experimental crosses. QTL mapping is typically based on the assumption that the traits follow normal distributions, which may not be true in ...interval ...

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Selecting Informative Traits for Multivariate Quantitative Trait Locus Mapping Helps to Gain Optimal Power

Selecting Informative Traits for Multivariate Quantitative Trait Locus Mapping Helps to Gain Optimal Power

... expression trait (e-trait) data of 211 recombi- nant inbred lines (RILs) that were derived from two parental inbred Arabidopsis thaliana accessions, Bayreuth-0 (Bay-0) and Shahdara (Sha), by selfing (Loudet ...

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Impact of gene expression data pre processing on expression quantitative trait locus mapping

Impact of gene expression data pre processing on expression quantitative trait locus mapping

... Another potential factor for explaining differences between methods is departure from normality of the phe- notypic distribution, especially when using a variance- component approach. We found that, in general, GCRMA led ...

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Linkage Disequilibrium on the Bovine X Chromosome: Characterization and Use in Quantitative Trait Locus Mapping

Linkage Disequilibrium on the Bovine X Chromosome: Characterization and Use in Quantitative Trait Locus Mapping

... for quantitative trait loci (QTL) affecting 48 traits of importance to the dairy industry and provide evidence for the presence of QTL affecting 5 of these traits on the bovine X ...

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Identification of glucosinolate profile in Brassica oleracea for quantitative trait locus mapping

Identification of glucosinolate profile in Brassica oleracea for quantitative trait locus mapping

... segregating mapping population sorted by trait type using the Win QTL Cartographer program with IM ...each trait, with positive effect associated with A12DH and negative effect associated with GD33DH ...

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Transcriptional Regulatory Pattern in Yeast Revealed through Expression Quantitative Trait Locus Mapping

Transcriptional Regulatory Pattern in Yeast Revealed through Expression Quantitative Trait Locus Mapping

... expression Quantitative Trait Locus (eQTL) analysis has been applied in yeast (Brem et ...eQTL mapping would guarantees that eQTL are significantly more likely to harbor biological elements ...

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Quantitative Trait Locus Mapping Based on Resampling in a Vast Maize Testcross Experiment and Its Relevance to Quantitative Genetics for Complex Traits

Quantitative Trait Locus Mapping Based on Resampling in a Vast Maize Testcross Experiment and Its Relevance to Quantitative Genetics for Complex Traits

... of polygenic quantitative traits such as grain yield. our results could be the assumption of only few segregat- Depending on the genetic architecture of the trait ing QTL (5 and 10) in the study by Moreau ...

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Honesty, power and bootstrapping in composite interval quantitative trait locus mapping

Honesty, power and bootstrapping in composite interval quantitative trait locus mapping

... interval mapping studies that have used Zmapqtl Model 6 of QTL ...provides quantitative bootstrap support for putative ...QTL mapping experiments were ac- companied by at least a modest set of ...and ...

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Estimation of Quantitative Trait Locus Effects with Epistasis by Variational Bayes Algorithms

Estimation of Quantitative Trait Locus Effects with Epistasis by Variational Bayes Algorithms

... ABSTRACT Bayesian hierarchical shrinkage methods have been widely used for quantitative trait locus mapping. From the computational perspective, the application of the Markov chain Monte Carlo ...

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Submergence Tolerant Rice: SUB1’s Journey from Landrace to Modern Cultivar

Submergence Tolerant Rice: SUB1’s Journey from Landrace to Modern Cultivar

... fine mapping of SUBMERGENCE 1 (SUB1), a robust quantitative trait locus from the submergence tolerant FR13A landrace, has enabled marker-assisted breeding of high-yielding rice capable of ...

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Model Selection in Binary Trait Locus Mapping

Model Selection in Binary Trait Locus Mapping

... Quantitative trait locus (QTL) mapping methodology for continuous normally distributed traits is the subject of much attention in the ...Binary trait locus (BTL) mapping ...

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The Dissection of Expression Quantitative Trait Locus Hotspots

The Dissection of Expression Quantitative Trait Locus Hotspots

... Let’s begin by considering the kidney chromosome 13 hot- spot (Figure 5, C and D). For these multivariate likelihood analyses, we focus on the top 50 expression traits mapping to the region in terms of their LOD ...

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Mapping and characterization of a quantitative trait locus resistance to the brown planthopper in the rice variety IR64

Mapping and characterization of a quantitative trait locus resistance to the brown planthopper in the rice variety IR64

... Results: Resistance genes in the rice variety IR64 were evaluated considering the seedling bulk test and seedling survival rate. As a result, a locus with a large LOD score of 7.23 was found between markers RM302 ...

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Mapping a Quantitative Trait Locus Involved in Melanotic Encapsulation of Foreign Bodies in the Malaria Vector, Anopheles gambiae

Mapping a Quantitative Trait Locus Involved in Melanotic Encapsulation of Foreign Bodies in the Malaria Vector, Anopheles gambiae

... Mapping a Quantitative Trait Locus Involved in Melanotic hcapsulation of Foreign Bodies in the Malaria Vector, Anopheles gambiae.. Maureen J.[r] ...

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Mapping of a Milk Production Quantitative Trait Locus to a 420-kb Region on Bovine Chromosome 6

Mapping of a Milk Production Quantitative Trait Locus to a 420-kb Region on Bovine Chromosome 6

... physical mapping was required for further ...hybrid mapping as well as BAC clones, the bovine and human comparative maps in the region are resolved, and the QTL is mapped within a distance of 420 ...

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Dietary obesity linked to genetic loci on chromosomes 9 and 15 in a polygenic mouse model

Dietary obesity linked to genetic loci on chromosomes 9 and 15 in a polygenic mouse model

... by Quantitative Trait Locus (QTL) analysis of two mapping populations derived from a cross between AKR/J and SWR/J ...F2 mapping population of 931 male mice we found significant linkage ...

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Mouse Inbred Strain Sequence Information and Yin-Yang Crosses for Quantitative Trait Locus Fine Mapping

Mouse Inbred Strain Sequence Information and Yin-Yang Crosses for Quantitative Trait Locus Fine Mapping

... these quantitative differences, the two re- and SNP databases for several mouse inbred strains pre- sources (RI strains and a set of inbred strains) are con- sents a novel resource, which might be applicable to ...

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