[PDF] Top 20 Development and Validation of an New High Performance Liquid Chromatography Method for Determination of Apixaban Isomers

... embolism. Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of ... See full document

... The calibration curve was plotted with five concentrations of the standard drug solution 10.0- 80.0ppm and chromatography was repeated five times for each dilution. The linearity was evaluated by linear regression ... See full document

... Accuracy of the method was established by performing recovery studies according to the ICH guidelines. Spiked samples were prepared by spiking pre-analyzed sample solutions with standard drug at three different ... See full document

... by high-performance liquid chromatography (HPLC) [3], determination of modafinil in human plasma by solid- phase and liquid-liquid extraction by HPLC [4-6] ... See full document

... its determination as drugs, in pharmaceutical formulation and in various biological fluids such as artificial neural network and near-infrared spectrometry [6], colorimetric [5], micellar enhanced ... See full document

... The percent recovery of Darifenacin hydrobromide was good under most conditions and didn’t show any significant change when the critical parameters were modified. The tailing factor for Darifenacin hydrobromide was ... See full document

... HPLC method that it is very friendly with the type of release ...This method exhibited best sensitivity, accuracy and precision for inter‑ and intra‑day ...proposed method is recommended as the ... See full document

... Atorvastatin calcium, chemically (3R,5R)-7-[2-(4- Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)- 1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt [1], is an inhibitor of the 3-hydroxy-3-methylglutaryl- ... See full document

... the development and validation of a new ultra high performance chromatography (UHPLC) procedure for the simultaneous determination of isoniazid (INH), rifampicin (RIF), ... See full document

... a new, simple, rapid, and precise stability indicating HPLC method was for the simultaneous estimation of Clindamycine, Metronidazole, and Clotrimazole in pharmaceutical dosage form, with less complex ... See full document

... The validation characteristics included accuracy, precision, specificity, linearity, and robust, and stability ...The method was demonstrated to be robust, resistant to small variations of chromatographic ... See full document

... HPLC method has been developed for the determination of ...proposed method is simple, rapid, accurate and ...HPLC method for the estimation of Rifabutin is simple and accurate in bulk and ... See full document

... The HPLC procedure was optimized with a view to develop a stability indicating assay method. Functional group analysis revealed the presence of acidic character to the molecules. Therefore we evaluated the ... See full document

... work new, simple reversed‑phase high performance liquid chromatographic method was developed and validated for the determination of hydroxychloroquine sulphate in blood ... See full document

... proposed method is applicable for the determination of Pyrantel pamoate and Febantel without interference and with good ...The method was validated entirely showing adequate data for all the ... See full document

... reversed-phase high-performance liquid chromatography (RP-HPLC) method for KET and ...[12-23], liquid chromatography–mass spectrometry [24], and ion-pair ... See full document

... Temperature was maintained ambient, mobile phase used was buffer: acetonitrile (55:45 v/v), and the flow rate was maintained at 1 ml/ min. The diluent used throughout the method was water: acetonitrile (50:50 v/v) ... See full document

... the development and validation of an analytical method by high performance liquid chromatography (HPLC) for the determination of catechin in a standardized dry ... See full document

... many determination methods already described in the literature, where some of them aim to simultaneously measure CUR and others curcuminoids employing HPLC based techniques (Jayaprakasha et ...simultaneous ... See full document

... A method using LC-ESI-MS/MS for the determina- tion of MEM in rat plasma employing simple liquid- liquid extraction was ...The method is rapid, simple, specific, and sensitive and additionally ... See full document