[PDF] Top 20 Formulation and In-vitro Evaluation of Matrix Controlled Lamivudine Tablets

... Human immune deficiency virus (HIV) is a retrovirus that can lead to acquired immunodeficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life threatening opportunistic ... See full document

... floating tablets: Domperidone was mixed with required quantity of polymer (HPMC K4M or carbopol 934P or SA), sodium bicarbonate and lactose in mortar for 5 min by using a ... See full document

... Formulation and the development of a pharmaceutical product is not complete without proper stability analysis, carried out on it to assess the physical and chemical stability and the ... See full document

... as matrix type sustained release drug delivery ...by matrix formation there by allow the drug to get solubility and absorption completely from intestinal ...like matrix upon ... See full document

... in vitro dissolution of Gliclazide can be enhanced by solid dispersion ...F6 formulation prepared by co-grinding method using Guar gum as carrier in 1:3 ratio shown the better release of Gliclazide ... See full document

... Tablets can be designed and manufactured to have separate layers or a core tablet inside a tablet. In this way, two or more drugs can be kept separate in a single tablet. Such complicated systems have found ... See full document

... formulate controlled release matrix tablets of nicotinic acid (NA), using xyloglucon (XGL), xanthan gum and guar gum separately, which tend to reduce “flushing” effect caused by immediate release of ... See full document

... G.A. Green 40 et al., Controlled-release (CR) medications offer many clinical and convenience advantages for patients as compared to immediate-release (IR) formulations. Among these are reductions of fluctuations ... See full document

... levofloxacin tablets were prepared by direct compression method. The tablets were evaluated for its hardness, weight variation, content uniformity and ...of tablets and it plays a vital role for drug ... See full document

... oral controlled-release drug delivery system is not just to sustain the drug release but also to prolong the presence of the dosage form within the gastrointestinal tract (GIT) until all the drug is completely ... See full document

... provide controlled drug release, although insoluble polymers have been ...hydrophobic matrix are water insoluble in ...hydrophobic matrix during drug ...hydrophobic matrix systems generally ... See full document

... hardness, thickness, diameter, weight variation and evaluated for drug content uniformity, drug release profiles was compared with pure drug. All the batches of matrix tablets prepared were found to be ... See full document

... floating matrix tablets of diltiazem ...Ram2,. Formulation and in-vitro evaluation gastroretentive drug delivery system of Cefixime for prolong ... See full document

... [1][2] Controlled release dosage forms have number of advantages over conventional dosage forms, such as improved patience compliance due to decrease in dosing frequencies, reduction in fluctuation in steady-state ... See full document

... (1). Controlled drug delivery technology is fast growing because of its many potential advantages like minimum fluctuations in plasma drug concentration and a reduced frequency of dosing when compared to the ... See full document

... compressible matrix tablets by direct compression has attracted much attention due to its technological simplicity in comparison with other controlled release ... See full document

... the matrix tablets was determined according to in-house standards and it meets the requirements if the amount of the active ingredient in each of the 3 tested tablets lies within the range of 90% to ... See full document

... Osmotically controlled oral drug delivery systems utilize osmotic pressure as energy source for the controlled delivery of drugs, independent of pH and hydrodynamic conditions of gastro intestinal tract ... See full document

... the matrix is much higher than drug solubility; ii) drug diffusion takes place only in one dimension iii) drug particles are much smaller than system thickness (iv) matrix swelling and dissolution are ... See full document

... The matrix tablets of various batches formulated were evaluated for test such as uniformity of weight, hardness, thickness, friability and drug ...tablet formulation was found to be (F1: ...all ... See full document