[PDF] Top 20 Integrated analysis of long non-coding RNAs in human colorectal cancer

... to human reference genome hg19 using TopHat [38] with default ...(DE) analysis from the raw counts and the results from the two packages were overlapped for further ... See full document

... of long non-coding RNAs (lncRNAs) in human cells and their crucial roles in various diseases, including cancers ...of RNAs with more than 200 nucleotides in length, which are not ... See full document

... in human CRC tissues and colon cancer cell ...mesenchymal-like cancer cells and primary CRC cancer tissues [27, ...in human colorectal cancer tissues and three cell lines ... See full document

... of rRNA by using an mRNA-ONLY Eukaryotic mRNA IsolationKit (Epicentre Biotechnologies, USA). Then, each sample was transcribed to double strand cDNA, then synthesized into cRNA and labeled with Cyanine-3-CTP. The labeled ... See full document

... in-depth analysis of ncRNAs in CRC has not been reported to ...by human genes, includ- ing miRNA, long noncoding RNA (lncRNA), circular RNA (circRNA), pRNA, and ... See full document

... microarray analysis results exhibited that HNF1A-AS1 was downregulated in GCs tissues (mean fold change ...adjacent non-neoplastic tissues (low expression, 94 of 161; low expression rate, ...multivariate ... See full document

... Two studies involved the multivariate Cox regression analysis of prognostic parameters including the expression of ANRIL in NSCLC patients. Ling et al (N = 87) and Nie et al (N = 68) had clinical follow-ups of 60 ... See full document

... threatened human life worldwide throughout ...of cancer are metastasis and recurrence. Cancer stem cells are a group of tumor cells that possess self-renewal and differentiation ability, which is a ... See full document

... of human GBM with no less than 40 ...for human GBM data sets that had no less than 50 samples and simultaneously available survival information in NCBI GEO and EBI ...needed human GBM gene expression ... See full document

... in human monocytes and monocytic cell lines have been extensively studied using both microarrays 1 and serial analysis of gene expression 2,3 ...both coding and non-coding regions of ... See full document

... after human genome sequencing, it became evident that although over 90% of the genome is actively transcribed [1, 2], the majority of transcripts is represented by non-coding RNA (ncRNA) and ... See full document

... (the human ortholog of PIWI) expression and diverse group of cancers including pancreatic [79] and gastric [80] adenocarcinomas, sarcomas [81], hepa- tocellular carcinomas [82], colorectal cancer ... See full document

... LncRNAs play critical roles in epigenetic modulation of chromatin structure by regulating key genes in spe- cific cancerous cells [186,187]. Distinct chromatin signa- tures are associated with lncRNAs encoding genes, and ... See full document

... and colorectal cancers [90, ...ovarian cancer tissues and cell ...gastric cancer, methylation of the MEG3 promoter has been linked to miR-148a down-regulation through its ability to target DNMT1 ... See full document

... informatics analysis of RNA-seq data identify that dia- betes can change the expression of several long ...Furthermore, human lncRNA E330013P06 genomic organization is similar to the mouse gene and ... See full document

... class of large intergenic non-coding RNAs (lincRNAs) [3]. The amenability of technology for deep sequencing of transcriptome [6] and computational tools to under- stand transcript diversity, ... See full document

... The meta-analysis was conducted with Stata 12.0 (Stata Corporation, College Station, TX, USA) and Meta-Disc 1.4 (XI Cochrane Colloquium, Barcelona, Spain) software. We calculated several primary outcomes, ... See full document

... Long non-coding RNAs (lncRNAs), typically >200bp, are nature prognostic biomarkers in indicating the intrinsic characteristics of cancer metastasis since they are the effector ... See full document

... primary human ovarian and endometrial cancers, confirming the H19/let-7- dependent regulation [39] ...ovarian cancer tissues, especially in malignant serous cystadenocarcinomas [40] ...ovarian cancer ... See full document

... Gene-level fragment counts for each polyA and total RNA sample were quantified using featureCounts v1.4.6 [53], using the flags: -p -s 2 -B -C -t exon -g gene_id. Count tables were normalized to Transcripts per Million ... See full document