[PDF] Top 20 Multiple sclerosis lesions: relationship between MR enhancement pattern and magnetization transfer effect

... the magnetization transfer ef- fect are quite complex, and although magneti- zation transfer imaging holds promise in pro- viding specific biochemical and biophysical information, it is still unclear ... See full document

... matter lesions in 18 patients, ages 18 to 65 years (mean age, ...gadolinium-enhanced MR and magnetization ...images, magnetization transfer images (see below), and 3- to 5-mm contiguous ... See full document

... In MR pattern A, probably only minor demyelina- tion occurs and may even be purely edematous or inflammatory in nature ...isointense lesions may represent the less aggressive lesions, as evi- ... See full document

... active lesions and form a major imaging marker for determining response to therapy or efficacy of new drugs; much activity is taking place that is not nec- essarily defined by enhancement ... See full document

... the relationship between the appearance of multiple sclerosis lesions identified on unenhanced T1-weighted images and their corresponding magnetization transfer ...matter ... See full document

... effects, lesions (indicated by white ar- rows on Fig 2) could be identified on both ihMTR and MTR maps and exhibited hypointensities compared with the surrounding nor- mal-appearing ...in lesions, which ... See full document

... diffusion-weighted MR imaging and showed a lack of correlation between average MTR and D ¯ of BT ...correlations between lesion MTR, D ¯ , and ...DT MR imaging provide relatively independent ... See full document

... matter lesions in multiple ...cortical lesions, it has not been fully optimized for visualization of white matter lesions and thus has not been used for delineating lesions in ... See full document

... contrast between gadolinium-enhanced im- aging with and without MTC is obvious, single-dose MTC and triple-dose gadolinium images were scored separately with an interval of 1 ...MS lesions were marked, and ... See full document

... hanced MR imaging for monitoring short-term MS evolution, either natural or modified by treatment (1, ...enhancing lesions in patients with MS ...this effect and its magnitude, thus suggesting that ... See full document

... of multiple sclerosis (MS) is judged on magnetic resonance (MR) images by plaque enhancement after intravenous injection of contrast material (1, ...Delayed MR imaging and ... See full document

... remitting multiple sclerosis (MS) using radiological and clinical ...various MR imaging sequences in order to assess both lesions and normal appearing brain tissue ...magnetisation ... See full document

... of enhancement is ...that lesions with higher degrees of enhancement should show more ...nonenhancing lesions appears to argue against this ...meaningful relationship between the ... See full document

... data. MR imaging was performed on a ...tion transfer (800/20/1; 5-mm sections with ...without magnetization transfer (800/ 20/1; 5-mm sections with ...tion transfer sequences were ... See full document

... categorize lesions with the same type of disease, we classified lesions into three groups depending on their appearance on T2-weighted images at the site of the MR spectroscopy voxel: group 1 was ... See full document

... in lesions detected in ex- perimental allergic encephalomyelitis, which is an animal model of ...MS lesions and that ADC was elevated in NAWM in patients with a benign disease ...no relationship ... See full document

... MS lesions and in the three areas of supratentorial normal-appearing white matter (NAWM) were obtained by averaging the pixel values in the regions of interest (ROIs) on the MTR ...the lesions on the ... See full document

... in these areas has been regarded as reflecting the pathologic conditions in pyramidal tract de- generation. In some cases, abnormal signals were also seen in the paraventricular white mat- ter and in the posterior limbs ... See full document

... differences between normal and multiple sclerosis (MS) brains are unknown, it has been shown that their global magnetization transfer ratio (MTR) values are significantly ...conversion ... See full document

... confluent lesions, it is possible that some of the discrete lesions seen on fast spin-echo images and not on fast FLAIR images were actually present on fast FLAIR images but not counted as separate ... See full document