[PDF] Top 20 Nonstructural proteins of herpes simplex virus. II. Major virus-specific DNa-binding protein.
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Nonstructural proteins of herpes simplex virus. II. Major virus-specific DNa-binding protein.
... When maximum levels of the ICSP 11,12 protein were attained about 18 h at 37°C postinfection Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The major herpes simplex vi[r] ... See full document
9
Phosphorylation of the Herpes Simplex Virus Type 1 Origin Binding Protein
... The herpes simplex virus type 1 (HSV-1) origin binding protein (OBP), the product of the UL9 gene, is one of seven HSV-encoded proteins required for viral DNA ...a ... See full document
10
Mutations that specifically impair the DNA binding activity of the herpes simplex virus protein UL42.
... bind DNA and were also im- paired for Pol binding, suggesting that those deletions either affected regions involved in both activities or otherwise caused a global misfolding of the protein ...UL42 ... See full document
7
Cellular Protein WDR11 Interacts with Specific Herpes Simplex Virus Proteins at the trans-Golgi Network To Promote Virus Replication
... with specific viral proteins, including gB, VP16, and VP5, but not ICP4, gC, or ...tegument proteins binding to one another as well as to the cyto- plasmic tails of envelope glycoproteins on ... See full document
12
ICP4, the major regulatory protein of herpes simplex virus, shares features common to GTP-binding proteins and is adenylated and guanylated.
... We conclude from these experiments the following: i only a small set of proteins in isolated nuclei from infected and mock-infected HeLa cells is labeled by [_x-32P]GTP; ii the labeling [r] ... See full document
11
Identification of a Region of the Herpes Simplex Virus Single-Stranded DNA-Binding Protein Involved in Cooperative Binding
... The herpes simplex virus type 1 (HSV-1) UL29 gene prod- uct, commonly designated ICP8, is the major single-strand- DNA-binding protein (SSB) present in infected ...viral ... See full document
9
Association between the herpes simplex virus major DNA-binding protein and alkaline nuclease.
... In this communication, we will demonstrate an interaction between two herpes simplex virus HSV-encoded proteins, the major DNAbinding protein and alkaline nuclease, which we believe must[r] ... See full document
10
Herpes simplex virus type 1 origin-specific binding protein: oriS-binding properties and effects of cellular proteins.
... Incubation of infected cell extracts with the lower-affinity site II DNA as a probe resulted in the appearance of two protein-DNA complexes with mobilities identical to those of the A an[r] ... See full document
11
Role of the UL25 Protein in Herpes Simplex Virus DNA Encapsidation
... UL25 protein is one of seven viral proteins that are required for DNA cleavage and ...of DNA-containing C capsids on the capsid ...multifunctional protein required: (i) to stabilize ... See full document
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Characterization of a major DNA-binding domain in the herpes simplex virus type 1 DNA-binding protein (ICP8).
... ICP8, the major DNA-binding protein from herpes simplex virus type 1 HSV-1, belongs to a class of singlestranded DNA-binding proteins.. These proteins are required for DNA replication, p[r] ... See full document
8
Characterization of the major mRNAs transcribed from the genes for glycoprotein B and DNA-binding protein ICP8 of herpes simplex virus type 1.
... 960 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The structural genes encoding the herpes simplex virus type 1 glycoprotein B and the major DNA-binding protein ICP8 [r] ... See full document
10
Genetic analysis of temperature-sensitive mutants which define the gene for the major herpes simplex virus type 1 DNA-binding protein.
... 354-366 0022-538X/83/010354-13$02.00/0 Copyright C 1983, American Society for Microbiology Genetic Analysis of Temperature-Sensitive Mutants Which Define the Gene for the Major Herpes Si[r] ... See full document
13
Comparison of the detection of herpes simplex virus in direct clinical specimens with herpes simplex virus specific DNA probes and monoclonal antibodies
... Comparison of the Detection of Herpes Simplex Virus in Direct Clinical Specimens with Herpes Simplex Virus-Specific DNA Probes and Monoclonal Antibodies JOAN C.. FUNG,1* JOHN SHANLEY,23 [r] ... See full document
6
Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein.
... In the absence of viral DNA replication, HSV Pol colocalized with the HSV DNA-binding protein ICP8 in nuclear framework-associated structures called prereplicative sites.. In the presenc[r] ... See full document
8
Mutations in the major DNA-binding protein gene of herpes simplex virus type 1 result in increased levels of viral gene expression.
... We have found that at the nonpermissive temperature, the synthesis of certain immediate early, early, and late viral polypeptides was greater in cells infected with the temperature-sensi[r] ... See full document
9
Identification of the gene encoding the 65-kilodalton DNA-binding protein of herpes simplex virus type 1.
... 818 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Hybrid arrest of in vitro translation was used to localize the region of the herpes simplex virus type 1 genome enco[r] ... See full document
8
Direct and Specific Binding of the UL16 Tegument Protein of Herpes Simplex Virus to the Cytoplasmic Tail of Glycoprotein E
... for virus entry in all other situations and is also known to be required for cell-to-cell spread (33, 55, 66, 67, 71, ...tegument proteins with gE might be needed for such a mech- ...GTPase-activating ... See full document
12
The herpes simplex virus Us11 open reading frame encodes a sequence-specific RNA-binding protein.
... Kovler Viral Oncology Laboratories, The University of Chicago, Chicago, Illinois 60637 Received 21 February 1990/Accepted 12 April 1990 In this paper we report that a protein encoded by [r] ... See full document
8
Purification of the herpes simplex virus type 1 65-kilodalton DNA-binding protein: properties of the protein and evidence of its association with the virus-encoded DNA polymerase.
... 8 Purification of the Herpes Simplex Virus Type 1 65-Kilodalton DNA-Binding Protein: Properties of the Protein and Evidence of Its Association with the Virus-Encoded DNA Polymerase MICHA[r] ... See full document
10
Expression of herpes simplex virus type 1 major DNA-binding protein, ICP8, in transformed cell lines: complementation of deletion mutants and inhibition of wild-type virus.
... In addition to cell lines which complemented ts mutants, two lines, U-27 and U-35, significantly inhibited plaque formation by wild-type virus, contained 30 and 100 copies of the ICP8 ge[r] ... See full document
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