[PDF] Top 20 Normal Appearing White Matter Changes Vary with Distance to Lesions in Multiple Sclerosis
Has 10000 "Normal Appearing White Matter Changes Vary with Distance to Lesions in Multiple Sclerosis" found on our website. Below are the top 20 most common "Normal Appearing White Matter Changes Vary with Distance to Lesions in Multiple Sclerosis".
Normal Appearing White Matter Changes Vary with Distance to Lesions in Multiple Sclerosis
... MR-visible lesions (both focal and diffuse) were outlined by an experienced observer on the fast spin-echo Pd/T2-weighted images, and from these, the total cerebral lesion volume—referred to as “lesion load”—was ... See full document
7
Voxel Based Analysis of Quantitative T1 Maps Demonstrates That Multiple Sclerosis Acts throughout the Normal Appearing White Matter
... MS lesions from the WM masks of the patients with MS creates holes with no data in their NAWM T1 ...MS lesions between patients, for any given voxel in standard space, there is a high probability that for ... See full document
7
Gene expression profiling of the astrocyte transcriptome in multiple sclerosis normal appearing white matter reveals a neuroprotective role
... Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the central nervous system ...(CNS). White matter lesions in MS are surrounded by areas of non- demyelinated ... See full document
25
Characterization of multiple sclerosis plaques with T1 weighted MR and quantitative magnetization transfer
... focal white matter lesions in guinea pigs with experimental allergic ...these lesions were edem- atous without demyelination. In white matter lesions identified on ... See full document
7
Characterisation of tissue type metabolic content in secondary progressive multiple sclerosis : a magnetic resonance spectroscopic imaging study
... progressive multiple sclerosis ...in white matter lesions compared with normal-appearing white matter, suggestive of higher myelin turnover (higher choline), ... See full document
8
Analysis of Normal Appearing White Matter in Multiple Sclerosis: Comparison of Diffusion Tensor MR Imaging and Magnetization Transfer Imaging
... individual lesions, the correlation between fractional anisotropy and MTR was modest (r 5 ...ab- normal WM in general, whereas MTR measure- ments are more specific in showing areas of sub- stantial ... See full document
8
Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis
... Fig. 1 Schematic representation of the experimental approach. Series of cryostat sections of post-mortem brain tissue, dissected from subcortical NAWM of 18 MS patients and 9 control subjects, were used for RNA ... See full document
19
Low Choline Concentrations in Normal Appearing White Matter of Patients with Multiple Sclerosis and Normal MR Imaging Brain Scans
... spinal MR imaging can reach almost 100% sensitivity. Of course, this raises the question of whether MS diagnosis is plausible in case subjects with a negative brain and spinal MR imaging. In our patient population, many ... See full document
7
Magnetization Transfer Imaging in Patients with Clinically Isolated Syndromes Suggestive of Multiple Sclerosis
... pathologic changes in multiple sclerosis (MS) ...the white matter that appears normal on studies obtained with conventional imaging techniques ...mal-appearing ... See full document
5
T1 Recovery Is Predominantly Found in Black Holes and Is Associated with Clinical Improvement in Patients with Multiple Sclerosis
... in normal-appearing white and gray matter during a 2-year follow-up in patients with primary-progressive MS and found a significant correlation between increasing T1- RTs and clinical ...MS ... See full document
6
Cortical Perfusion Alteration in Normal Appearing Gray Matter Is Most Sensitive to Disease Progression in Relapsing Remitting Multiple Sclerosis
... T1 changes (in milliseconds) in response to the contrast agent injections (precontrast versus postcontrast) used as part of a DSC perfusion ...T1 changes in normal-appearing white ... See full document
8
A Comparison of Magnetization Transfer Ratio, Magnetization Transfer Rate, and the Native Relaxation Time of Water Protons Related to Relapsing remitting Multiple Sclerosis
... imaging: normal-ap- pearing white matter (NAWM), diffuse white matter changes, and focal non-acute and acute ...Diffuse white matter changes comprised areas ... See full document
7
Magnetic resonance spectroscopy of normal appearing white matter in early relapsing-remitting multiple sclerosis: correlations between disability and spectroscopy
... demyelinating lesions and one area of normal appearing white matter in MS patients and in one area of normal white matter in the healthy control ... See full document
10
MAGNETIC RESONANCE SPECTROSCOPY OF NORMAL APPEARING WHITE MATTER IN EARLY RELAPSING-REMITTING MULTIPLE SCLEROSIS
... acute lesions and in NAWM of MS patients , indicating that elevated levels of Glu are involved in the progression of MS even in this non-lesional MS ...no white matter lesions are found ]28 [ ... See full document
8
Early relapsing remitting multiple sclerosis: A magnetic resonance imaging study investigating normal appearing brain tissue and lesion changes and their relationship to clinical disability
... remitting multiple sclerosis (MS) using radiological and clinical ...both lesions and normal appearing brain tissue ...in lesions and ...of changes in diffusivity and ... See full document
205
Localisation of citrullinated proteins in normal appearing white matter and lesions in the central nervous system in multiple sclerosis
... to multiple post-translational modi fi cations that have important consequences for its structure and functions (Middeldorp and Hol, ...MS lesions have not received major attention; however, the above ... See full document
12
Production of IL-16 correlates with CD4+ Th1 inflammation and phosphorylation of axonal cytoskeleton in multiple sclerosis lesions
... chronic lesions, and lower but still above normal levels in normal appearing white matter, may be due to generalization of inflammatory and degenerative processes beyond focal ... See full document
13
Measurement of Volumetric Lesion Load in Multiple Sclerosis: Moving from Normal to Dirty Appearing White Matter
... images. Changes in MTR likely indicate, for example, alter- ations in chemical exchange of bulk water associated with that bound to the macromolecular environment ...macromolecular changes in those ... See full document
6
Magnetization transfer: a potential method to determine the age of multiple sclerosis lesions
... Normal-appearing white matter in all of the patients with multiple sclerosis had magnetization transfer effect values ranging from 0.41 to 0.45.. The magnetization transfer effect value [r] ... See full document
6
The common marmoset ( Callithrix jacchus ): a relevant preclinical model of human (auto)immune-mediated inflammatory disease of the brain
... visualize white- matter lesions, as depicted in Fig. 1b. Once lesions of suf- ficient size for quantification of inflammatory activity were detected, treatment with the antibody or placebo was ... See full document
14
Related subjects