[PDF] Top 20 Physical characterization of the herpes simplex virus latency-associated transcript in neurons.
Has 10000 "Physical characterization of the herpes simplex virus latency-associated transcript in neurons." found on our website. Below are the top 20 most common "Physical characterization of the herpes simplex virus latency-associated transcript in neurons.".
Physical characterization of the herpes simplex virus latency-associated transcript in neurons.
... 1194 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest RNA transfer Northern blot analysis was used to perform the physical characterization of the transcript expressed i[r] ... See full document
9
Transcription of the Herpes Simplex Virus Latency-Associated Transcript Promotes the Formation of Facultative Heterochromatin on Lytic Promoters
... modifications associated with cHC (22, 57), it was also possible that the genome was associated with ...also associated with lytic gene promoters, albeit to lower levels than ...classically ... See full document
9
Herpes Simplex Virus Latency-Associated Transcript Sequence Downstream of the Promoter Influences Type-Specific Reactivation and Viral Neurotropism
... During latency, HSV-1 and HSV2-LAT-S1 did not re- activate ...chimeric virus, which contained both the HSV-1 LAT promoter and sequence, implying that an interaction of the HSV-2 LAT promoter and HSV-1 LAT ... See full document
9
The 2.2-Kilobase Latency-Associated Transcript of Herpes Simplex Virus Type 2 Does Not Modulate Viral Replication, Reactivation, or Establishment of Latency in Transgenic Mice
... HSV-2 latency and the factors that induce reactivation have been the subjects of extended ...in latency. The gene encoding these latency-associated transcripts (LATs) (5, 22) is about 9 kb ... See full document
7
A Novel Herpes Simplex Virus Type 1 Transcript (AL-RNA) Antisense to the 5′ End of the Latency-Associated Transcript Produces a Protein in Infected Rabbits
... LAT transcript that do not block transcription of the remainder of LAT (21, ...this transcript does not overlap any of the LAT RNA it is unlikely to account for the altered virulence seen for mutants ... See full document
8
Two herpes simplex virus type 1 latency-active promoters differ in their contributions to latency-associated transcript expression during lytic and latent infections.
... primary transcript, perhaps the ...recombinant virus that contained the simian virus 40 poly(A) site upstream of the putative LAT splice acceptor sequence ... See full document
10
Tissue-Specific Splicing of the Herpes Simplex Virus Type 1 Latency-Associated Transcript (LAT) Intron in LAT Transgenic Mice
... Abundant LAT expression is seen in a variety of tissues and is not age dependent. The transgenic mouse was then analyzed for the amount of LAT RNA produced in different tissues by real-time RT-PCR using primers specific ... See full document
10
A herpes simplex virus type 1 latency-associated transcript mutant reactivates with normal kinetics from latent infection.
... Expression of herpes simplex virus type 1 latency-associated transcripts in the trigeminal ganglia of mice during acute infection and reactivation of latent infection.. Expression of her[r] ... See full document
10
The herpes simplex virus type 1 2.0-kilobase latency-associated transcript is a stable intron which branches at a guanosine.
... Is LAT intron stability mediated through a guanosine branchpoint? Some introns use nonadenosine branch points in vivo (reviewed in reference 48). The second intron of the human immunodeficiency virus type 1 ... See full document
10
Characterization of Herpes Simplex Virus 2 Primary MicroRNA Transcript Regulation
... in latency and reactivation is unclear (19, 35, 47–54), with a possible LAT-inde- pendent role in viral recurrence reported in ...primary transcript, which starts just downstream of the LAT tran- scription ... See full document
12
Herpes Simplex Virus Type 1 Latently Infected Neurons Differentially Express Latency-Associated and ICP0 Transcripts
... HSV-1 latency (20, ...(TG) neurons (9, ...during latency, as recently reported by Chen et ...sensory neurons in vivo (6, 26, 27, * Corresponding ... See full document
12
CTCF-Dependent Chromatin Boundary Element between the Latency-Associated Transcript and ICP0 Promoters in the Herpes Simplex Virus Type 1 Genome
... activity associated with the larger ...systematic characterization and molecular definition of a viral insulator that appears to func- tion as chromatin boundary element to separate the regulatory activity ... See full document
10
Coregulatory Interactions among CD8α Dendritic Cells, the Latency-Associated Transcript, and Programmed Death 1 Contribute to Higher Levels of Herpes Simplex Virus 1 Latency
... leukemia virus (MuLV) reverse transcriptase from a High Capacity cDNA reverse tran- scription kit (Applied Biosystems, Foster City, CA), in accordance with the manufacturer’s ... See full document
12
The latency-associated transcript gene of herpes simplex virus type 1 (HSV-1) is required for efficient in vivo spontaneous reactivation of HSV-1 from latency.
... In both experiments, the decreased spontaneous reactivation rate of the LAT deletion mutant compared with the parental or rescued virus was statistically significant McKrae versus dLAT29[r] ... See full document
11
Importance of NKT Cells in Resistance to Herpes Simplex Virus, Fate of Virus-Infected Neurons, and Level of Latency in Mice
... We have shown recently that CD1d-dependent NKT cells are important in the early stages of the immune response to HSV-1 (15). Others have made similar observations in infec- tions with other viruses (13, 18, 40). NKT ... See full document
11
Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript.
... In summary, we have i used transient CAT assays in neuron-derived cells to map LAT-associated promoter activity to a location over 660 nucleotides upstream from the 5' end of the stable [r] ... See full document
10
The Herpes Simplex Virus Type 1 Locus That Encodes the Latency-Associated Transcript Enhances the Frequency of Encephalitis in Male BALB/c Mice
... LAT transcript is indicated by the large ...recombinant virus that was constructed using dLAT2903, and it contains a fragment spanning from ⫺ 1800 to ⫹ ...recombinant virus that was constructed using ... See full document
5
Herpes simplex virus type 1 latency-associated transcript (LAT) promoter deletion mutants can express a 2-kilobase transcript mapping to the LAT region.
... The data for KOS/29 LAT-related RNA expression suggest the presence of a second promoter in the LAT gene which can function in tissue culture infection, at low levels in acute infection [r] ... See full document
8
Herpes Simplex Virus Type 1 2-Kilobase Latency-Associated Transcript Intron Associates with Ribosomal Proteins and Splicing Factors
... longer associated with the intact translational ...remains associated with the intact translational machin- ery, reinforcing the idea that maintenance of efficient transla- tion is critical for viral RNA ... See full document
11
Detection of herpes simplex virus type 1 latency-associated transcript expression in trigeminal ganglia by in situ reverse transcriptase PCR.
... We had previously demonstrated that use of LAT expression detected by ISH as a measure of the number of genome- containing cells underestimates the number of latent HSV genome-containing cells in a trigeminal ganglion. ... See full document
5
Related subjects