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Multiscale Modelling

Multiscale modelling of endocrine systems: new insight on the gonadotrope axis

Multiscale modelling of endocrine systems: new insight on the gonadotrope axis

... Abstract. In vertebrates, the gonadotrope axis is made up of the hypothalamus, belonging to the central nervous system, the pituitary gland and the gonads. These organs communicate with one another within entangled ...

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A multiscale modelling approach for estimating the effect of defects in unidirectional carbon fiber reinforced polymer composites

A multiscale modelling approach for estimating the effect of defects in unidirectional carbon fiber reinforced polymer composites

... A multiscale modelling approach was developed in order to estimate the e ff ect of defects on the strength of unidirectional carbon fiber ...The modelling approach was tested with a unidirectional ...

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Seven challenges in the multiscale modelling of multicellular tissues

Seven challenges in the multiscale modelling of multicellular tissues

... with multiscale modelling of multicellular tissue ...infer multiscale model parameters from partial information on processes at each scale) to the computational (how to unambiguously define such ...

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Multiscale modelling of intestinal crypt organization and carcinogenesis

Multiscale modelling of intestinal crypt organization and carcinogenesis

... and multiscale modelling to study later steps in colorectal ...by modelling a vertical cross-section through a crypt as a U-shaped chain of growing, deformable elastic ...

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Multiscale modelling of cancer progression and treatment control : the role of intracellular heterogeneities in chemotherapy treatment

Multiscale modelling of cancer progression and treatment control : the role of intracellular heterogeneities in chemotherapy treatment

... complex, multiscale process involving interactions at intracellular, intercel- lular and tissue scales that are in turn susceptible to microenvironmental ...hybrid multiscale modelling approaches, ...

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How does multiscale modelling and inclusion of realistic palaeobathymetry affect numerical simulation of the Storegga Slide tsunami?

How does multiscale modelling and inclusion of realistic palaeobathymetry affect numerical simulation of the Storegga Slide tsunami?

... a multiscale simulation, where grid resolution varies spatially, often by orders of magnitude (Piggott et ...2008). Multiscale models often use an unstructured mesh, so in addition can accurately represent ...

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Multiscale Modelling of Microstructure Evolution under Radiation Damage of Steels Based on Atomistic to Mesoscale Methods

Multiscale Modelling of Microstructure Evolution under Radiation Damage of Steels Based on Atomistic to Mesoscale Methods

... In order to simulate the microstructure evolution with the objective to predict it, multiscale modelling tools are developed (Fig. 1). For this purpose different simulation methods are used and developed in ...

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Multiscale modelling of drug polymer nanoparticle assembly identifies parameters influencing drug encapsulation efficiency

Multiscale modelling of drug polymer nanoparticle assembly identifies parameters influencing drug encapsulation efficiency

... the multiscale simulations the solvent is only modelled at the coarse-grained level and so does not have any electrostatic ...Our multiscale parameterisation increases the coarse-grained phosphate-water ...

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Multiscale modelling methods in biomechanics

Multiscale modelling methods in biomechanics

... As a resolution to the problem MSK_PA6 posed ear- lier, Szczesny and Elliot, in two consecutive papers, 45,46 reported predictive accuracy for their multiscale model of a tendon fascicle comprising dis- ...

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Accelerating multiscale modelling of fluids with on the fly Gaussian process regression

Accelerating multiscale modelling of fluids with on the fly Gaussian process regression

... We present a scheme for accelerating hybrid continuum-atomistic models in multiscale fluidic systems by using Gaussian process regression as a surrogate model for computationally expensive molecular dynamics ...

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Nonlinear multiscale modelling of quasi solid state behaviour of PET/MWCNT nanocomposites : 3D RVE based approach

Nonlinear multiscale modelling of quasi solid state behaviour of PET/MWCNT nanocomposites : 3D RVE based approach

... The rheological behaviour of entangled polymers and their nanocomposites under those conditions is challenging to capture with a mathematical model that can further be used in numerical simulations and optimization of ...

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Multiscale modelling of materials chemomechanics : brittle fracture of oxides and semiconductors

Multiscale modelling of materials chemomechanics : brittle fracture of oxides and semiconductors

... Modelling the crack tip region at the QM level in this way reproduces the expected brittle behaviour of silicon, as illustrated in Fig. 2(b). For the case of silicon, the fracture initiates at a much reduced ...

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Multiscale modelling of auxin transport in the plant root elongation zone

Multiscale modelling of auxin transport in the plant root elongation zone

... using multiscale asymptotic methods which enable us to derive simplified descriptions of the tissue-scale dynamics, identifying the key contributions of the cell-scale pro- ...

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Multiscale Modelling for Cerebrospinal  Fluid Dynamics: Multicompartmental Poroelacticity and the Role of AQP4

Multiscale Modelling for Cerebrospinal Fluid Dynamics: Multicompartmental Poroelacticity and the Role of AQP4

... physical multiscale model can explore the relationship between CSF and glial cells via the incorporation of AQPs (as microscopic channels) and elaborate on the macroscopic manifestations of this ...

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Multiscale Modelling Of Platelet Aggregation

Multiscale Modelling Of Platelet Aggregation

... the multiscale model did not treat whole-clot fracture from the surface (embolism), the steady state clot thickness of 50 μm (~85% occlusion of the 60-μm channel) occurred when the wall shear rate experienced on ...

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1 A multiscale modelling approach for estimating the

1 A multiscale modelling approach for estimating the

... with a unidirectional carbon fiber composite beam, from which the micromechanical model was.. 20.[r] ...

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Multiscale modelling tool : mathematical modelling of collective behaviour without the maths

Multiscale modelling tool : mathematical modelling of collective behaviour without the maths

... MuMoT is available as source code, as a package for Python 3 [27] via PyPI ( pypi.python. org), and as a server-based installation currently exemplified by free-to-use access to the interactive user manual and other ...

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Multiscale modelling of industrial flighted rotary dryers

Multiscale modelling of industrial flighted rotary dryers

... their modelling. However, there is extensive description of modelling both unflighted and flighted drums in ...the modelling strategy for the flighted sections was based on a compartment ...

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Multiscale modelling of the respiratory track: 
a theoretical framework

Multiscale modelling of the respiratory track: a theoretical framework

... a modelling point of view, the suitability of this approach is highly questionable, as our 2D upper tree cannot be expected to reproduce all features of the real, three-dimensional ...

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Multiscale Modelling of Nuclear Fuels under Irradiation

Multiscale Modelling of Nuclear Fuels under Irradiation

... a multiscale modeling scheme of nuclear fuels will be presented, with some examples of applications making use of atomic scale approaches: First-principles electronic structure calculations used to get insight ...

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