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Type I Error Rate

Sample size re-assessment leading to a raised sample size does not inflate type I error rate under mild conditions

Sample size re-assessment leading to a raised sample size does not inflate type I error rate under mild conditions

... tive under the conditions of this paper. From this follows that the normal approximation of G(r) is non-positive for k satisfying the above condition. Finally, invoke the fast convergence of the binomial distribution ...

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A Simulation Based Comparison of Correlation Coefficients with Regard to Type I Error Rate and Power

A Simulation Based Comparison of Correlation Coefficients with Regard to Type I Error Rate and Power

... In general, Permutation-based Pearson correlation coefficient and especially the Winsorized correlation coef- ficient are most robust to the distribution shape, sample size, and outliers. Thus, it is possible to ...

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Minimum number of clusters and comparison of analysis methods for cross sectional stepped wedge cluster randomised trials with binary outcomes: A simulation study

Minimum number of clusters and comparison of analysis methods for cross sectional stepped wedge cluster randomised trials with binary outcomes: A simulation study.

... good type I error rate and bias characteristics when compared to the other methods while maintaining similar if not superior power despite the distribution of the random intercept being ...

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A Quick Method for Computing Approximate Thresholds for Quantitative Trait Loci Detection

A Quick Method for Computing Approximate Thresholds for Quantitative Trait Loci Detection

... genome-wise type I error rate of tests for quantitative trait locus (QTL) detection in interval mapping (IM) and composite interval mapping ...

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Dichotomizing partial compliance and increased participant burden in factorial designs: the performance of four noncompliance methods

Dichotomizing partial compliance and increased participant burden in factorial designs: the performance of four noncompliance methods

... hypothesis of the study question. In this case, employing ITT to estimate the treatment effect will not inflate the type I error rate of the test. This great benefit of ITT comes at the cost ...

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Mapping Quantitative Trait Loci in Noninbred Mosquito Crosses

Mapping Quantitative Trait Loci in Noninbred Mosquito Crosses

... The results from the mosquito intercross data at marker positions as well as results from interval QTL mapping scanning through the chromosome at every 2 cM are plotted in Figure 3 for chromosome 2 and in Figure 4 for ...

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On the Prospects of Whole-Genome Association Mapping in Saccharomyces cerevisiae

On the Prospects of Whole-Genome Association Mapping in Saccharomyces cerevisiae

... higher type I error rate in cis-based association ...the type I error rate was again elevated above nominal ...expected rate of 0.05, we found that the ...

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Population Admixture: Detection by Hardy-Weinberg Test and Its Quantitative Effects on Linkage-Disequilibrium Methods for Localizing Genes Underlying Complex Traits

Population Admixture: Detection by Hardy-Weinberg Test and Its Quantitative Effects on Linkage-Disequilibrium Methods for Localizing Genes Underlying Complex Traits

... the type I error rate of association studies under various scenarios of population differentiation and ...elevates type I error rate for detecting genes underlying ...

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Comparison of three tests of homogeneity of odds ratios in multicenter trials with unequal sample sizes within and among centers

Comparison of three tests of homogeneity of odds ratios in multicenter trials with unequal sample sizes within and among centers

... the type I error rate of the three homogeneity tests is approximately close to the nominal level of ...same type I error rate, power comparisons are ...

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Two stage phase II oncology designs using short term endpoints for early stopping

Two stage phase II oncology designs using short term endpoints for early stopping

... Ray-Coquard et al. [16] used nine-month progression-free survival. This delay causes problems in trials with interim analyses, such as the Simon two-stage design. In this paper we assume that recruitment is paused once ...

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An internal pilot study with interim analysis for Gaussian linear models

An internal pilot study with interim analysis for Gaussian linear models

... of type I error rate, power (under any alternative), and expected sample size for any general linear univariate model with Gaussian errors and fixed ...maximum type I ...

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Increased risk of type I errors in cluster randomised trials with small or medium numbers of clusters: a review, reanalysis, and simulation study

Increased risk of type I errors in cluster randomised trials with small or medium numbers of clusters: a review, reanalysis, and simulation study

... the type I error rate even with a small number of clusters; however, it can lead to reduced power compared to mixed-effects models or GEEs; as such, these latter approaches are much more ...

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A Comparison of Statistics for Assessing Model Invariance in Latent Class Analysis

A Comparison of Statistics for Assessing Model Invariance in Latent Class Analysis

... noninvariant LCA model provided better fit to the data, while the BIC, CAIC and aBIC all suggested that the best fit was given by the constrained model. Based on the results of the simulation study described previously, ...

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Value of information methods to design a clinical trial in a small population to optimise a health economic utility function

Value of information methods to design a clinical trial in a small population to optimise a health economic utility function

... the type I error rate, α , is usu- ally restricted at a one-sided ...the error rate for that hypothesis test on the primary outcome is consistent with a utility maximisation ...

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Psioda_unc_0153D_16507.pdf

Psioda_unc_0153D_16507.pdf

... the type I error rate and statistical power of the design over a range of possible parameter values for the generative model in the new ...

139

A Comparative Study on Sensitivity of Multivariate Tests of Normality to Outliers

A Comparative Study on Sensitivity of Multivariate Tests of Normality to Outliers

... the Type I error rate and power of some multivariate normality tests at various levels of significance under different sample sizes and dimensions of multivariate ...that Type 1 ...

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Controlling the False Discovery Rate of the Association/Causality Structure Learned with the PC Algorithm    (Special Topic on Mining and Learning with Graphs and Relations)

Controlling the False Discovery Rate of the Association/Causality Structure Learned with the PC Algorithm    (Special Topic on Mining and Learning with Graphs and Relations)

... discovery rate (FDR) (see Benjamini and Yekutieli, 2001; Storey, 2002), defined as the expected ratio of falsely discovered positive hypotheses to all those discovered, has become an important and widely used ...

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Non-Normality and Heteroscedasticity in Regression and ANOVA

Non-Normality and Heteroscedasticity in Regression and ANOVA

... the Type I error rate drastically increases when the lowest variance is in the largest sample size group and greatest variance in the smallest sample size ...on Type I ...

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How does under-reporting of negative and inconclusive results affect the false-positive rate in meta-analysis? A simulation study

How does under-reporting of negative and inconclusive results affect the false-positive rate in meta-analysis? A simulation study

... the type I error rate for the publication bias tests were also ...Additionally, I estimated the type I error rate for the test of the mean effect size using ...

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CPMCGLM: an R package for p-value adjustment when looking for an optimal transformation of a single explanatory variable in generalized linear models

CPMCGLM: an R package for p-value adjustment when looking for an optimal transformation of a single explanatory variable in generalized linear models

... We applied the various types of correction method described in this article to correct the type-I error rate in the model defined above. These corrections are easy to apply with the CPMCGLM ...

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