[PDF] Top 20 Allele Frequency Distribution Under Recurrent Selective Sweeps
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Allele Frequency Distribution Under Recurrent Selective Sweeps
... the frequency spectrum under the recurrent sweep ...low frequency, background selection may further skew the frequency spectrum in the di- rection of negative Tajima’s D (C harlesworth ... See full document
12
Selective Sweeps in the Presence of Interference Among Partially Linked Loci
... called selective sweeps, assumed that at most one beneficial allele is on the way to fixation at a given ...of recurrent selective sweeps is ...on recurrent ... See full document
10
Linkage Disequilibrium as a Signature of Selective Sweeps
... evolutionary Selective sweeps cause drastic changes in (i) the spatial process of great interest is the occurrence of a beneficial distribution of polymorphic sites, (ii) the frequency ... See full document
12
A Microsatellite-Based Multilocus Screen for the Identification of Local Selective Sweeps
... recent selective sweep at one or a few loci by the reduction in ...4.—Frequency distribution of the number of sig- expansion for highly variable loci (large ... See full document
11
Selective Sweeps in Multilocus Models of Quantitative Traits
... an allele that affects a polygenic trait selected toward a phenotypic ...an allele at a given locus is less likely when it starts at low frequency and the other locus is polymorphic (with alleles at ... See full document
23
Limited Evidence for Classic Selective Sweeps in African Populations
... specific selective pressures often remain ...hard selective sweeps using several haplotype and allele-frequency statistics with a data set of nearly 500,000 genome-wide single- ... See full document
111
Refining the Use of Linkage Disequilibrium as a Robust Signature of Selective Sweeps
... the distribution of each statistic under neutrality by simulating 1000 samples for each demo- graphic and recombination ...the distribution of the test statistics given a positive selective ... See full document
41
Detecting Bottlenecks and Selective Sweeps From DNA Sequence Polymorphism
... of allele frequencies is identical to ...expected under constant population size and low , together sites of equal “size” ...the frequency distribution of these alleles), incompatible with ... See full document
7
DISTRIBUTION OF GENE FREQUENCY AS A TEST OF THE THEORY OF THE SELECTIVE NEUTRALITY OF POLYMORPHISMS
... In the absence of selec- tion, the steady-state variation in frequency of an allele at a locus from popula- tion t o population, or from time to time, is entirely a reflection of [r] ... See full document
21
Soft Shoulders Ahead: Spurious Signatures of Soft and Partial Selective Sweeps Result from Linked Hard Sweeps
... as sweeps in the human genome using iHS (Voight et ...completed sweeps (Williamson et ...the frequency of recurrent hitchhiking events, which may cause much of the genome to resemble a ...soft ... See full document
31
Effects of Linked Selective Sweeps on Demographic Inference and Model Selection
... inference (@a@i) (Gutenkunst et al. 2009), use the probability density of the site frequency spectrum (SFS) under a given de- mographic model and parameterization to calculate the likeli- hood of the ... See full document
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Detection of selective sweeps in structured populations : a comparison of recent methods
... Figure Legends Figure 1: Results for the island model: a trace of the allele frequency of the selected variant in the selected population, Y, and in a neutral population, Z with migratio[r] ... See full document
30
Patterns of Neutral Diversity Under General Models of Selective Sweeps
... the recurrent full-sweep model, in which newly arisen selected alleles fix ...of recurrent selective sweeps in a coalescent framework, one that generalizes the recurrent full-sweep model ... See full document
22
Gene-specific selective sweeps in bacteria and archaea caused by negative frequency-dependent selection
... prokaryotes under NFDS was devel- oped (our model is very similar to that described in Hodgson and Otto [41], except that it incorporates neu- tral loci, but does not assume modifier ...beneficial allele ... See full document
11
Selective Sweeps and Parallel Pathoadaptation Drive Pseudomonas aeruginosa Evolution in the Cystic Fibrosis Lung
... ABSTRACT Pulmonary infections caused by Pseudomonas aeruginosa are a recalcitrant problem in cystic fibrosis (CF) patients. While the clinical implications and long-term evolutionary patterns of these infections are well ... See full document
14
Joint Effects of Self-Fertilization and Population Structure on Mutation Load, Inbreeding Depression and Heterosis
... spatial distribution of organisms and their mode of reproduction have important effects on the change in allele frequencies within ...against recurrent deleterious ...the frequency of ... See full document
16
On the Distribution of Temporal Variations in Allele Frequency
... locus under the null hypothesis (drift is homogeneous throughout the genome) and simultaneously controls the rate of false positive among loci declared as departing significantly from the ... See full document
6
Selective Sweeps
... Chevin et al. (2008) explicitly modeled the case of two closely linked, selected loci, and one neutral locus for infi- nitely large populations using ordinary differential equations. Similar to Kim and Stephan (2003), ... See full document
9
Original Article Association of MSX1 genetic polymorphisms with non-syndromic cleft lip with or without cleft palate in a uyghur population in Xinjiang, China
... and allele through snapshot ...and allele whether fit Hardy-Weinberg law of genetic ...Results: Distribution of rs3821949 genotypes, Minor allele carriers (AG+GG) and Minor allele ... See full document
6
THE SAMPLING DISTRIBUTION OF LINKAGE DISEQUILIBRIUM UNDER AN INFINITE ALLELE MODEL WITHOUT SELECTION
... T h e sampling distributions of several statistics that measure the association of alleles on gametes (linkage disequilibrium) are estimated under a two-locus neutral infinite [r] ... See full document
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