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[PDF] Top 20 Intermolecular interactions and protein dynamics by solid state NMR spectroscopy

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Intermolecular interactions and protein dynamics by solid state NMR spectroscopy

Intermolecular interactions and protein dynamics by solid state NMR spectroscopy

... The research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013)/ ERC Grant Agreement 639907. J.R.L. also acknowledges ... See full document

7

Probing intermolecular interactions in a diethylcarbamazine citrate salt by fast MAS 1 H solid state NMR spectroscopy and GIPAW calculations

Probing intermolecular interactions in a diethylcarbamazine citrate salt by fast MAS 1 H solid state NMR spectroscopy and GIPAW calculations

... Probing intermolecular interactions in a diethylcarbamazine citrate salt by fast MAS 1 H solid-state NMR spectroscopy and GIPAW ...calculations. Solid State Nuclear ... See full document

22

Methods for the determination of the structures and dynamics of proteins by solid state NMR spectroscopy

Methods for the determination of the structures and dynamics of proteins by solid state NMR spectroscopy

... the protein samples used in SSNMR experiments must still be hydrated in order for internal dynamic processes to ...within protein molecules have a substantial averaging effect on the anisotropic ... See full document

225

Investigating interactions using solid state NMR: applications to biomolecular complexes

Investigating interactions using solid state NMR: applications to biomolecular complexes

... solution NMR if a protein tumbles too ...and dynamics measurements, but for the samples that are fully protonated 90-100 kHz MAS is used to get high quality ...large protein complexes or other ... See full document

183

Investigating sensitivity improvement methods for quadrupolar nuclei in solid state nuclear magnetic resonance

Investigating sensitivity improvement methods for quadrupolar nuclei in solid state nuclear magnetic resonance

... the NMR phenomenon and NMR spec- troscopy. The interactions described in the previous chapter, the static magnetic field and the application of RF pulses, are controlled by the user and, as such, are ... See full document

489

Unraveling the complexity of protein backbone dynamics with combined 13C and 15N solid state NMR relaxation measurements

Unraveling the complexity of protein backbone dynamics with combined 13C and 15N solid state NMR relaxation measurements

... picosecond-nanosecond protein motions in solution and hydrated protein ...that intermolecular interactions, ...of dynamics in solution and hydrated crystal are very consistent over a ... See full document

13

Conformational dynamics of a seven transmembrane helical protein anabaena sensory rhodopsin probed by solid state NMR

Conformational dynamics of a seven transmembrane helical protein anabaena sensory rhodopsin probed by solid state NMR

... interactions (and on the effective reduction of heteronuclear dipolar interactions under MAS) through the dilution of the proton bath by perdeuteration with back-exchange of the amide and other ... See full document

52

Solid state NMR of a protein in a precipitated complex with a full length antibody

Solid state NMR of a protein in a precipitated complex with a full length antibody

... 20 solid-state NMR spectroscopy of proteins with high concentrations of protons at magic-angle spinning (MAS) frequencies of 60 − 100 kHz, in the absence and presence of paramagnetic doping to ... See full document

8

Solid State NMR Spectroscopic Approaches to Investigate Dynamics, Secondary Structure and Topology of Membrane Proteins

Solid State NMR Spectroscopic Approaches to Investigate Dynamics, Secondary Structure and Topology of Membrane Proteins

... significant protein systems ...membrane-bound protein systems make the crystallization process very ...membrane protein structures have been obtain via X-ray crystallography ...natively, ... See full document

8

Protein Ligand Interactions by NMR and EPR Spectroscopy

Protein Ligand Interactions by NMR and EPR Spectroscopy

... the protein (Yagi et ...frozen state are very likely maintained in liquid ...molecular dynamics simulations of molecules without tag at about 300 K, which were combined with rotamers of the metal tag ... See full document

206

Probing intermolecular crystal packing in γ indomethacin by high resolution (1)H solid state NMR spectroscopy

Probing intermolecular crystal packing in γ indomethacin by high resolution (1)H solid state NMR spectroscopy

... of NMR crystallography of organic solids employs experimental solid-state NMR usually in combination with calculation to probe solid-state ...the interactions that govern ... See full document

25

Probing intermolecular interactions and three dimensional packing of organic molecules by solid state NMR

Probing intermolecular interactions and three dimensional packing of organic molecules by solid state NMR

... high-resolution solid-state NMR spectra (under Magic Angle Spinning) such that key structural information can be determined for crystalline powder sam- ...the NMR signal are described, notably ... See full document

228

Biological Membrane Structure By Solid-State NMR

Biological Membrane Structure By Solid-State NMR

... (NMR) spectroscopy has become a method of choice for the study of the structure and dynamics of natural and synthetic ...multidimensional NMR techniques has brought a versatile approach to the ... See full document

7

Longer range distances by spinning angle encoding solid state NMR spectroscopy

Longer range distances by spinning angle encoding solid state NMR spectroscopy

... acquisition of the free-induction decay, so as to obtain optimum sensitivity. The retention of both ideal resolution and long-range distance sensitivity was achieved by redesigning a 600 MHz HX MAS NMR probe to ... See full document

6

Structural Insights into Group 14 Compounds from Solid-State NMR Spectroscopy

Structural Insights into Group 14 Compounds from Solid-State NMR Spectroscopy

... computational NMR studies. Previous computational studies of 73 Ge NMR parameters 14,15,18,25 have made use of the plane wave pseudopotential method in the CASTEP program, which has proven to be an ... See full document

231

Evaluating lithium diffusion mechanisms in the complex spinel Li2NiGe3O8

Evaluating lithium diffusion mechanisms in the complex spinel Li2NiGe3O8

... (Fig. 9), in good agreement with the value obtained from EIS data on a pellet sintered for 6 h (0.46 0.01 eV), but considerably lower than that observed after a 24 h sinter (0.53 0.01 eV). This is further evidence that ... See full document

9

The development of solid state NMR methodology to study the dynamics of proteins and ice

The development of solid state NMR methodology to study the dynamics of proteins and ice

... Two types of ultracentrifuge rotors are used with these tools: fixed angle and swinging bucket (Figure 3.6). A fixed angle rotor can typically reach higher speeds than a swinging bucket rotor, however the force produced ... See full document

258

How does ytterbium chloride interact with DMPC bilayers?:A computational and experimental study

How does ytterbium chloride interact with DMPC bilayers?:A computational and experimental study

... mixture of lipids and proteins that form the cellular membrane determine the dynamics and structure of the bilayer. In order to explain the role that lipids play within the cell both in struc- ture and signalling ... See full document

11

Bio-Solid State NMR

Bio-Solid State NMR

... Magic angle spinning solid state NMR narrows anisotropically broadened spectra.. Small (Mr ~ 3k) peptide in fluid lipid bilayers Static NMR spectrum.[r] ... See full document

44

Techniques of solid-state NMR

Techniques of solid-state NMR

... Sanchez 'Surface and bulk characterisation of titanium oxo clusters and nanosized titania particles through 17O solid state NMR.' J. All transitions exhibit second order effects[r] ... See full document

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