[PDF] Top 20 The pattern of neutral molecular variation under the background selection model.

... Infinite sites population model: The approximate analytical results generated previously suggested that, at least with low mutation rates, no difference in the effect [r] ... See full document

... effectively neutral mutations and is greater for smaller mutation sizes (Figure 5), which is consistent with the decrease of the mean selection coefficients of larger mutations (Figure ...behavior ... See full document

... this model include only coding ...X/A neutral diversity values; an excess variance in male re- productive success due to sexual competition, or a female- biased sex ratio, would cause an even higher value ... See full document

... genetic variation, ...general model for the interaction of a major mutation or a novel environment with the additive genetic basis of a quantitative character under stabilizing ...genetic ... See full document

... null model (P ⫽ 0.08). However, when the non-African sequence variation at two introns of Dmd in a worldwide populations are considered collectively, there is a sig- sample of 41 humans and found that these ... See full document

... Approximate formulas are derived for the reduction below classical neutral values resulting from such background selection against deleterious mutations, for the mean times [r] ... See full document

... directional selection on favorable alleles (causing hitchhiking effects on linked neutral polymorphisms) is expected to occur while a deleteri- ous mutation-selection balance is present in a ... See full document

... and background selection on statistics such as the number of segregating sites, the number of haplotypes, and measures of linkage disequilibrium, which are often included in inference methods ...include ... See full document

... To test whether patterns of mitochondrial DNA (mtDNA) variation are consistent with a neutral model of molecular evolution, nucleotide sequences were determined for the 1041 bp of the NA[r] ... See full document

... a model that considers that all deleterious mutations have the same effect on fitness is a simplifica- tion, we also studied the pattern of neutral variation under a two-type ... See full document

... multiallelic model is untractable analyt- then considered a set of d identical demes of constant ically and was analyzed using simulations (see computer size ... See full document

... window selection, noise, the number o f segments ...proper selection o f this parameters is even more im portant and difficult to p redict if calculating bicoherence ... See full document

... to model ‘ion-scale’ flux tubes in the Earth’s ...quasineutral model approaches a nonlinear force-free configuration in the limit of a vanishing electron to ion mass ...their model, current is ... See full document

... of selection for driving adaptive evolution ...natural selection of favourable variations, and that those variations are con- stituted by random mutations and recombination in a Mendelian ...natural ... See full document

... radicals produced by complex I are vectored only in the direction of matrix, while the superoxide radi- cals from complex III are released both into matrix and into intermembrane space (and hence into cyto- sol). Other ... See full document

... Purifying selection against number of segregating (or polymorphic) sites, we define slightly deleterious mutations is not efficient in popula- S * ⫽ S/a 1 , ... See full document

... small molecular bonding ...the molecular design of NPBAs could have high fiexibility which can change the solubility of NPBAs in the slurry by adjusting the composition and content of ... See full document

... The results provide strong support for variable selection intensity among amino acid sites The neutral model is rejected in favor of the positive-selection model, indicating the operatio[r] ... See full document

... Now regard k as a random variable with probability-generating function given by (1) and let the random variable x be the mobility difference between the protein products of two [r] ... See full document

... We also obtain results on the possible strength of selection induced on a tightly linked neutral modifier, and show that it is on the order of the variation in equili[r] ... See full document