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D-optimal experimental design

Optimization and Validation of the Simultaneous Determination of Vildagliptin and Metformin, in Bulk and Formulation by A Reverse Phase HPLC Method Using D-Optimal Experimental Design

Optimization and Validation of the Simultaneous Determination of Vildagliptin and Metformin, in Bulk and Formulation by A Reverse Phase HPLC Method Using D-Optimal Experimental Design

... A simple, rapid, sensitive and economical analytical method has been effectively created utilizing the precise approach for evaluation of VLD and MET in bulk drug and also in-house tablet formulations. The ideal setting ...

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Simulation-Based Bayesian Experimental Design using Mutual Information.

Simulation-Based Bayesian Experimental Design using Mutual Information.

... a D-optimal experimental ...on D- optimal points from local D-optimal designs centered at maximum likelihood estimates could converge to a D-optimal ...a ...

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Design and Optimization of Controlled Release Felbamate Tablets by D-optimal Mixture Design: In vitro-in vivo Evaluation

Design and Optimization of Controlled Release Felbamate Tablets by D-optimal Mixture Design: In vitro-in vivo Evaluation

... the experimental procedures were carried out as per the guidelines of the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA), ...

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Process Improvement of Experimental Measurements Using D-optimal Models

Process Improvement of Experimental Measurements Using D-optimal Models

... non-linear design space, but they are unstable and they need a broad range of sample points, particularly in high ...the design space into ...engineering design is multi- objective. Barton 5 has ...

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Optimization of Moisturizing Clay Soap Containing Pitaya (Hylocereus Polyrhizus) Seed Extract using D Optimal Mixture Experimental Design

Optimization of Moisturizing Clay Soap Containing Pitaya (Hylocereus Polyrhizus) Seed Extract using D Optimal Mixture Experimental Design

... The responses were applied in order to fit the suitable model (linear or quadratic) after the formulation had been analysed. The model was tested for goodness of fit correlation of determination (R 2 ) and analysis of ...

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Optimal Design of Non-equilibrium Experiments for Genetic Network Interrogation

Optimal Design of Non-equilibrium Experiments for Genetic Network Interrogation

... SE- optimal design criteria resulted in lower normalized standard errors (NSE) for each parameter as compared to optimizing the time points τ or the naive experimental design (Table ...SE- ...

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Optimal Design Based on Dynamic Characteristics and Experimental Implementation of Submersible Electromagnetic Actuators

Optimal Design Based on Dynamic Characteristics and Experimental Implementation of Submersible Electromagnetic Actuators

... with the optimization results. Figs. 7b and d are the calculated velocity and acceleration according to the displacement of the plunger. They clearly differ from the simulated velocity and acceleration shown in ...

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A two-loop optimization strategy for multi-objective optimal experimental design

A two-loop optimization strategy for multi-objective optimal experimental design

... The D-optimal criterion is used to measure the data information and the design result is shown in Table ...the design result suggests the measurement of S to be taken from 10 to 15 minutes and ...

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The Construction of Locally D Optimal Designs by Canonical Forms to an Extension for the Logistic Model

The Construction of Locally D Optimal Designs by Canonical Forms to an Extension for the Logistic Model

... a design can be easily ...for optimal experimental design theory: the general equivalence ...proposed design is D -optimal or ...

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An optimal experimental design perspective on redial basis function regression

An optimal experimental design perspective on redial basis function regression

... predictive D-optimality via RVM in multivariate ...of optimal experimental design for linear models, with an emphasis on the maximum a posteriori (MAP) estimation and the corresponding ...

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Optimal Experimental Design For Semiconductor Lifetime Mission Profile Testing

Optimal Experimental Design For Semiconductor Lifetime Mission Profile Testing

... the optimal selection of the design ...chosen design, an approximated full factorial design, a D-optimal design without prior and a D-optimal design ...

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Optimal Design for Parameter Estimation in EEG Problems in a 3D Multilayered Domain

Optimal Design for Parameter Estimation in EEG Problems in a 3D Multilayered Domain

... as Optimal Experimental ...finding optimal number and locations for sensors for source identification in a 3D unit sphere from data on its ...classical D-optimal criterion for ...

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Optimal Raw Material Mix for the Production of Rice Husk Ash Blended Cement

Optimal Raw Material Mix for the Production of Rice Husk Ash Blended Cement

... (14) experimental runs of RHA-blended cements were generated using three-factor D- optimal design (RHA, Ordinary Portland Cement (OPC) clinker and ...determined. Design- Expert ...The ...

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Experimental design approach to optimal and kinetic evaluation of coag flocculation performance of afzelia bella extract in coal washery effluent

Experimental design approach to optimal and kinetic evaluation of coag flocculation performance of afzelia bella extract in coal washery effluent

... pinning optimal conditions for ABC driven coag-flocculation performance in ...response. Optimal operation was recorded at pH6, 300mg/l dosage and 30 minutes settling time at the conditions of the ...

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Enhancement of physicochemical properties of nanocolloidal carrier loaded with cyclosporine for topical treatment of psoriasis: in vitro diffusion and in vivo hydrating action

Enhancement of physicochemical properties of nanocolloidal carrier loaded with cyclosporine for topical treatment of psoriasis: in vitro diffusion and in vivo hydrating action

... A D-optimal mixture experimental design was used in the optimization of nanoemulsion compositions, in order to understand the relationships behind the effect of independent variables (oil, ...

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Experimental Investigations to Determine Optimal Cutting Parameters in Grinding Operations by Design of Experiments
Bareddy Ramamohan Reddy & Sri P Ch Sreenivasababu

Experimental Investigations to Determine Optimal Cutting Parameters in Grinding Operations by Design of Experiments Bareddy Ramamohan Reddy & Sri P Ch Sreenivasababu

... The following works are done by some authors on grinding operations B. Dasthagiri, Dr. E. VenugopalGoud[1], mainly focuses on developing the empirical models using response surface methodology for surface roughness and ...

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Optimal design techniques for distributed parameter systems

Optimal design techniques for distributed parameter systems

... believe optimal design is useful when the number of observations that can be collected is similar to the number of parameter values to be ...without optimal design will work well, although it ...

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Optimal Design for Minimizing Uncertainty in Dynamic Equilibrium Systems

Optimal Design for Minimizing Uncertainty in Dynamic Equilibrium Systems

... Current efforts in modeling the host immune response to HIV infection and RNA3 recruitment in the Brome Mosiac Virus (BMV) replication cycle have elucidated the relationship between disturbances that drive biological ...

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Development and validation of RP-HPLC method for pitavastatin calcium in bulk and formulation using experimental design

Development and validation of RP-HPLC method for pitavastatin calcium in bulk and formulation using experimental design

... simplex design. A simplex centroid design with axial points in a pseudo-component representation was generated from the pure mixture ...augmented design points were tested to separate the drug in ...

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Optimization of a synthetic mixture composed of major Trichoderma reesei enzymes for the hydrolysis of steam-exploded wheat straw

Optimization of a synthetic mixture composed of major Trichoderma reesei enzymes for the hydrolysis of steam-exploded wheat straw

... In the present study, we analyzed the hydrolysis of a single substrate, steam-pretreated wheat straw, by a six component mixture at different stages. An experimental mixture plan was set up for the four major T. ...

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