HPMC K15M
HPMC K15M and Carbopol 940 mediated fabrication of ondansetron hydrochloride intranasal mucoadhesive microspheres
... polymers; HPMC K15M and Carbopol 940 ...and HPMC K15M (P-series)/Cb (N-series) were dissolved in 50 mL of ethanol by means of a magnetic ...
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FORMULATION OF PIOGLITAZONE FLOATING TABLETS: A COMPARATIVE EVALUATION OLIBANUM, STARCH ACETATE AND HPMC K15M
... employing HPMC K15M, olibanum and starch acetate were of good quality with regard to drug content, hardness and ...and HPMC K15M and sodium bicarbonate at 20% ...and HPMC as matrix ...
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IN VITRO RELEASE KINETICS STUDY OF TRAMADOL HCl SUSTAINED RELEASE MATRIX TABLET FROM HPMC K15M
... cellulose K15M, Lactose, Microcrystalline cellulose (Avicel pH 101), Magnesium Stearate, and Talc was obtained from Dhaka University laboratory 12 ...(HPMC K15M), and excipients (Avicel, lactose) ...
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Optimization of Polymer Concentration for Designing of Oral Matrix Controlled Release Dosage Form
... Diclofenac sodium 300 mg tablets were prepared with different concentrations (20, 30, 40 and 50%) of HPMC (K15M). Tablets were uniform in weight and hardness. Figure 3 shows the mean percentage of drug ...
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Formulation and invitro evaluation of floating matrix tablets of mitiglinide
... using HPMC K15M, as release retarding polymer along with other ionic and anionic polymeric ...using HPMC K15M and sodium alginate, as release retarding polymers were giving satisfactory ...
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Formulation and Evaluation of Floating Tablets using Nimesulide as a Model Drug
... The tablets prepared with low viscosity grade HPMC K4M (i.e. F1, F2, and F3) exhibited short Floating Lag Time and longer Floating Time, when compared with the formulations containing high viscous grade ...
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EFFECT OF DIFFERENT GRADES OF HPMC AND EUDRAGIT ON DRUG RELEASE PROFILE OF DOXOFYLLINE SUSTAINED RELEASE MATRIX TABLETS AND IVIVC STUDIES
... viz., HPMC K4M, HPMC K15M and hydrophobic matrix polymer ...of HPMC used, HPMC K15M having better controlled release profile than HPMC ...using HPMC polymer alone ...
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Formulation and Characterisation of Clarithromycin controlled released Bioadhesive Tablets
... methylcellulose K15M, Hydroxypropyl methylcellulose K4M, Carbopol 974P, used as hydrophilic matrix forming and bioadhesive polymer in varying concentration along with Magnesium stearate, talc and Lactose as ...
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Development and evaluation of ranitidine hydrochloride floating matrix tablet
... In conclusion, in the present research, the floating tablet of ranitidine hydrochloride were successfully prepared by using HPMC K4M, HPMC K15M and Carbopol 940 to increase the gastric residence time ...
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Formulation and evaluation of controlled release matrix tablet of Albuterol sulphate
... of HPMC K15M (X1) and HPMC K100M (X2) were selected as independent variables, whereas initial release at the (Y1, % drug release), (Y2, % drug Content) the concentration of Were chosen as dependent ...
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FORMULATION DEVELOPMENT AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS OF VERAPAMIL HYDROCHLORIDE
... CONCLUSION: The Sustain released matrix tablet form of Verapamil hydrochloride was prepared by wet granulation technique. Various pre compression properties of the prepared formulations were done which include bulk ...
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FORMULATION AND EVALUATION OF ACYCLOVIR MATRIX TABLET USING MUCOADHESIVE POLYMER
... FT-IR spectra matching approach was used for detection of any possible chemical interaction between the acyclovir and polymers. The samples were ground, mixed thoroughly with KBr and compressed at a pressure of 15tons ...
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FORMULATION, DEVELOPMENT & EVALUATION OF NOVEL SUSTAINED RELEASE ORODISPERSIBLE TABLETS OF ROPINIROLE HCL BY SPRAY DRYING TECHNIQUE
... The in-Vitro release data was applied to various kinetic models to predict the drug release kinetic mechanism. The release constant was calculated from the slope of appropriate plots and the regression coefficient (r 2 ) ...
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Formulation of gastro retentive drug delivery of ciprofloxacin and its evaluation
... Ciprofloxacin, obtained from Fourrts India Ltd, India as a gift sample. HPMC K15M, sodium alginates were purchased from central drug house, Mumbai. Sodium bicarbonate, Calcium carbonate, Micro crystalline ...
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Effect of polymer diluent ratio on physicochemical properties of matrix tablets of aceclofenac sodium for oral controlled drug delivery
... of HPMC K15M and Pharmatose 200M ratio in the ...of HPMC K15M forms loose network gel layer which rapidly diffuses the drug at higher pH ...of HPMC K15M in the matrix tablets ...
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EFFET OF COMBINATION OF HPMC AND CARBOPOL 934P ON THE PROPERTIES OF THE GASTRIC FLOATING TABETS OF TIMOLOL MALEATE
... Optimum swelling index was seen for tablets of batch F8 containing 120 mg of HPMC K100M and 20 mg of Carbopol 934P as compared to other formulations. The nominal viscosity of F8 was found to be more than 1,04,120 ...
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Development of modified release tablet dosage forms of capecitabine for better therapeutic efficacy
... & HPMC K15M) as drug release ...of HPMC used, K15M was selected as release retardant based on viscosity in controlling the CPC release during ...of HPMC K15M and MCC (Avicel ...
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FORMULATION AND EVALUATION OF SUSTAINED RELEASE FLOATING TABLETS OF LORATADINE
... CONCLUSION: The present investigation was carried out to develop gastro-retentive sustained release formulation of Loratadine for an effective and safe therapy by using a natural polymer and a synthetic polymer, i.e. ...
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FORMULATION AND IN-VITRO EVALUATION GASTRORETENTIVE DRUG DELIVERY OF TINIDAZOLE
... The aim of the current study was to design oral controlled release gastro-retentive drug delivery of Tinidazole. that are designed to retain in the stomach for a long time and have developed as a Local drug delivery ...
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Journal of Applied Pharmaceutical Science
... of HPMC K100M and K15M is ...use HPMC K15M as the swellable polymer in our further ...from HPMC K15M matrix formulations is shown in Figure ...of HPMC K15M ...
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