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Estimating Effective Population Size or Mutation Rate With Microsatellites

Estimating Effective Population Size or Mutation Rate With Microsatellites

... sample size and mean square error (MSE) for the corresponding n → ∞, ␪ ˜ F has a limit value, which does not depend on estimates are then computed and the results are summa- ...sample size is rized in Table ... See full document

10

Mutation Rate Variation at Human Dinucleotide Microsatellites

Mutation Rate Variation at Human Dinucleotide Microsatellites

... and mutation rate is thus an important parameter governing the extent of genetic ...variation. Microsatellites are highly informative genetic markers that have been widely used in genetic ...the ... See full document

8

A Low Mutation Rate For Chloroplast Microsatellites

A Low Mutation Rate For Chloroplast Microsatellites

... of mutation rates at SSR loci is im- eters: (1) initial denaturation at 948 for 3 min; (2) 30 cycles of denaturation at 948 for 15 sec, annealing at 608 for 15 sec, portant because they determine levels of ... See full document

5

Estimating effective population size or mutation rate using the frequencies of mutations of various classes in a sample of DNA sequences.

Estimating effective population size or mutation rate using the frequencies of mutations of various classes in a sample of DNA sequences.

... The neutral Wright-Fisher model is the simplest model in coalescent theory and is often selected to be the null model in studying DNA polymorphisms.. Simulated samples[r] ... See full document

12

Estimating effective population size and mutation rate from sequence data using Metropolis-Hastings sampling.

Estimating effective population size and mutation rate from sequence data using Metropolis-Hastings sampling.

... The method is somewhat more successful when it begins from a reasonable genealogy (data not shown). Genealogies from the short chains should not be used in the final es[r] ... See full document

10

Microsatellite Mutations and Inferences About Human Demography

Microsatellite Mutations and Inferences About Human Demography

... of population variability does not tion variance depends linearly on features of the muta- depend on making the correct assumption about a par- tion mechanism (the mutation mean square, ␩ 2 , and ticular ... See full document

15

The Amount of DNA Polymorphism Maintained in a Finite Population When the Neutral Mutation Rate Varies Among Sites

The Amount of DNA Polymorphism Maintained in a Finite Population When the Neutral Mutation Rate Varies Among Sites

... Fu, Y.-X., 1994b Estimating effective population size or mutation rate using the frequencies of mutations of various classes in a sample of DNA sequences. B., 1983 Es[r] ... See full document

9

Once lost, diversity of gene pools cannot be restored

Once lost, diversity of gene pools cannot be restored

... Levels of genetic diversity within species are controlled by mutation rates, the size of the breeding population effective population size, and the pattern and strength of natural select[r] ... See full document

6

Joint Prediction of the Effective Population Size and the Rate of Fixation of Deleterious Mutations

Joint Prediction of the Effective Population Size and the Rate of Fixation of Deleterious Mutations

... the minimum number of mutations, will get an additional deleterious mutation at any locus and the least-loaded class will disappear to be replaced by a new fittest class with one more mutation. Without ... See full document

28

Neutrality Tests Using DNA Polymorphism From Multiple Samples

Neutrality Tests Using DNA Polymorphism From Multiple Samples

... a population reflects not A number of statistical tests can be extended for multi- only mutations in the ancestors of the sequences but ple ...molecular population genet- difference between two estimates of ... See full document

6

Estimating Effective Population Size and Migration Rates From Genetic Samples Over Space and Time

Estimating Effective Population Size and Migration Rates From Genetic Samples Over Space and Time

... focal population, but it does not make any assumptions ...for estimating assumption affects only the precision, not the accuracy the effective size, migration rate, or their product N e ... See full document

18

Polymorphism aware species trees with advanced mutation models, bootstrap and rate heterogeneity

Polymorphism aware species trees with advanced mutation models, bootstrap and rate heterogeneity

... the effective population size which is assumed con- ...birth rate was set such that the expected number of species for the given height is ...HKY mutation model (Hasegawa et ... See full document

8

Empirical Bayes Procedure for Estimating Genetic Distance Between Populations and Effective Population Size

Empirical Bayes Procedure for Estimating Genetic Distance Between Populations and Effective Population Size

... Kitada, S., K. Hiramatsu and H. Kishino, 1994 Estimating mortal- Wright, S., 1969 Evolution and Genetics of Populations: The Theory of ity rates from tag recoveries: incorporating over-dispersion, corre- Gene ... See full document

18

Multivariate analysis of genomic variables, effective population size, and mutation rate

Multivariate analysis of genomic variables, effective population size, and mutation rate

... Finally, we performed EFA analysis to disclose any hid- den relationships among genomic variables and Neu. Perhaps Neu affects genome evolution by indirectly mod- ulating genomic variables, and we may see some hidden ... See full document

6

Population Genetics of Caenorhabditis elegans: The Paradox of Low Polymorphism in a Widespread Species

Population Genetics of Caenorhabditis elegans: The Paradox of Low Polymorphism in a Widespread Species

... sample size 23, under a given set of parameter ...stepwise mutation model with a mutation rate of ...current effective population size was set at 14,000, which is ... See full document

12

The Effects of Variable Mutation Rates Across Sites on the Phylogenetic Estimation of Effective Population Size or Mutation Rate of DNA Sequences

The Effects of Variable Mutation Rates Across Sites on the Phylogenetic Estimation of Effective Population Size or Mutation Rate of DNA Sequences

... Under the neutral Wright-Fisher model without re- combination and population subdivision, we study the effects of multiple hits due to mutation rate heterogene- ity among s[r] ... See full document

11

A phylogenetic estimator of effective population size or mutation rate.

A phylogenetic estimator of effective population size or mutation rate.

... These two estimates are unbiased under the infinite- site neutral Wright-Fisher model, that is under the assumptions that the population evolves according to the Wright-Fishe[r] ... See full document

8

Estimating Mutation Rate: How to Count Mutations?

Estimating Mutation Rate: How to Count Mutations?

... Mutation rate is an essential parameter in genetic ...premeiotic mutation events, so that the number of mutant individuals can be significantly larger than the number of mutation events ... See full document

10

The Effective Size of a Subdivided Population

The Effective Size of a Subdivided Population

... identity due to coalescence in some particular genera- tion, T '. This is given by the probability of a coalescence in some deme k at time T ' , multiplied by the probability tha[r] ... See full document

15

EFFECTS OF RESTRICTED POPULATION SIZE AND INCREASE IN MUTATION RATE ON THE GENETIC VARIATION OF QUANTITATIVE CHARACTERS

EFFECTS OF RESTRICTED POPULATION SIZE AND INCREASE IN MUTATION RATE ON THE GENETIC VARIATION OF QUANTITATIVE CHARACTERS

... The effects of population size and increase in mutation rate on the mean and genetic variance of quantitative characters and the genetic load associated with these characters ha[r] ... See full document

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