microarray experiments
Microarray experiments and factors which affect their reliability
... of microarray studies are limited, since the measurement of transcript levels provides only a rough estimate of the intracellular conditions at a spe- cific time point, and is affected by a plethora of ...
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Distributional fold change test – a statistical approach for detecting differential expression in microarray experiments
... microarray experiments, different statistical methods have been used to systematically extract biological information and to quantify the associated ...
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Advanced spot quality analysis in two colour microarray experiments
... standardize microarray data analysis pipelines ...of microarray platforms [5]. A critical component of the microarray data analysis pipe- line is image ...improving microarray anal- ysis, one ...
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How many replicates of arrays are required to detect gene expression changes in microarray experiments? A mixture model approach
... size/power calculations in clinical trials and other experi- ment designs; the (to-be-determined) sample size in microarray experiments refers to the number of replicates, whereas the number of genes is not ...
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Fast Gene Ontology based clustering for microarray experiments
... gene sets with hundreds of genes that are typically seen in microarray experiments. We then combined expression data and GO annotations using hierarchical clustering and a heat map visualisation that ...
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Design of Microarray Experiments for Genetical Genomics Studies
... slide, microarray experi- ments using two-color systems impose a block structure with blocks of size ...slide, microarray experiments involve an additional blocking factor to be accounted for, which ...
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A Normalized Tree Index for identification of correlated clinical parameters in microarray experiments
... (the microarray data) help to formulate new hypothesis and aid to obtain new insights into the complex mechanisms of ...the microarray data are probably not based on direct causal ...the microarray ...
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HAMSTER: visualizing microarray experiments as a set of minimum spanning trees
... for microarray data, our application of MSTs is most related to the work on data clustering by researchers at the Oak Ridge National Laboratory/University of ...a microarray data set and then apply ...
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GeneRank : using search engine technology for the analysis of microarray experiments
... a microarray experiment, where we would like a gene to be highly ranked if it is linked to other highly ranked genes, even if its own position is lower, ...
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Development and application of a microarray meter tool to optimize microarray experiments
... optimization experiments are almost always required [1- ...a microarray control set. A robust microarray control set should a) be easy to implement, b) be applicable to a wide variety of spotting ...
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Automated detection of regions of interest for tissue microarray experiments: an image texture analysis
... The standard procedure in clinical assessment of invasive breast cancer is the classification of the tumor into one of the three distinct histology grades [1]. Main difficulties related to grading of breast cancer in a ...
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Identification of novel long non-coding RNAs in clear cell renal cell carcinoma
... the microarray experiments using an independent cohort of 55 ccRCC and 52 normal renal tissue samples and to confirm the success of siRNA-mediated lncRNA knock- ...
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A novel dimensionality reduction technique based on independent component analysis for modeling microarray gene expression data
... DNA microarray experiments generating thousands of gene expression measurements, are being used to gather infor- mation from tissue and cell samples regarding gene expres- sion differences that will be ...
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Development and Clinical Evaluation of a Highly Sensitive DNA Microarray for Detection and Genotyping of Human Papillomaviruses
... DNA microarray hybridization shows a high degree of ...DNA microarray analysis with cell ...DNA microarray, we carried out HPV DNA microarray hybridization with HPV-positive and -negative cell ...
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Glutamine supplementation suppresses herpes simplex virus reactivation
... RNA microarray experiments comparing gene expression of latently HSV-1–infected mouse trigeminal ganglia for animals treated with supplemental glutamine and those treated with ...independent ...
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Transcriptome analysis of leaf and root of rice seedling to acute dehydration
... plants. Microarray experiments using mRNA from air-dried leaves and roots of rice were performed in an attempt to study genes involved in dehydration ...
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Differential timing of gene expression regulation between leptocephali of the two Anguilla eel species in the Sargasso Sea
... of microarray experiments with American and European eel leptocephali collected in the Sargasso Sea in order to test the alternative hypotheses of (1) differential timing of gene expression regulation ...
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LONETSSOM Platform: Enabling Distributed Processing, Managing and Mining of Biological Data through Fusion of Logical Network and Web Technologies in NETWORK Infrastructure
... DNA microarray processing scenarios, can be particularly variable, even for the first part of the quantitative analysis, which concerns the signal processing phase and the derivation of significant gene lists, the ...
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Assessing the translatability of In vivo cardiotoxicity mechanisms to In vitro models using causal reasoning
... from microarray experiments from dif- ferent sources, models and chips, thus overcoming tech- nical and biological variability that otherwise make the comparison at the gene level ...
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Differential timing of gene expression regulation between leptocephali of the two Anguilla eel species in the Sargasso Sea
... of microarray experiments involv- ing leptocephali of American and European eels collected at the same time and in the same environment in the Sargasso Sea with the goal of documenting for the first time ...
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