[PDF] Top 20 Temperature-sensitive transformation by Rous sarcoma virus and temperature-sensitive protein kinase activity.
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Temperature-sensitive transformation by Rous sarcoma virus and temperature-sensitive protein kinase activity.
... Although it could be argued that endogenous p6farc does not transform a normal cell because of a fundamental and as yet undetected difference between it and viral p6src, it can equally w[r] ... See full document
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Localization of temperature-sensitive transformation mutations and back mutations in the Rous sarcoma virus src gene.
... 694 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Cloning and sequencing of two temperature-sensitive transforming mutations of Rous sarcoma virus reveal that their l[r] ... See full document
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p21 of Kirsten murine sarcoma virus is thermolabile in a viral mutant temperature sensitive for the maintenance of transformation.
... SCOLNICK Laboratory of Tumor Virus Genetics, National Cancer Institute, Bethesda, Maryland 20205 We have recently described an intracellular protein, p21, in nonproducer cells transforme[r] ... See full document
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Vaccinia virus morphogenesis is blocked by temperature-sensitive mutations in the F10 gene, which encodes protein kinase 2.
... isolated temperature-sensitive (ts) mutants of vaccinia virus WR (ts28, ts54, ts61, and ts15) composing a single complementation group have been mapped by marker rescue to the F10 open reading frame ... See full document
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Cooperative transformation studies with temperature-sensitive mutants of Rous sarcoma virus.
... The present report deals with the methods used for the isolation of ts mutants from stocks of Bryan high-titer RSV of the morphr and morpht type of morphological conversion 14, with the [r] ... See full document
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Product of in vitro translation of the Rous sarcoma virus src gene has protein kinase activity.
... We have therefore addressed the question of the temperature sensitivity of the protein kinase associated with the p6O8rc of ts NY68 by comparison of the specific activities of the protei[r] ... See full document
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Temperature-Sensitive Transformation by an Abelson Virus Mutant Encoding an Altered SH2 Domain
... leukemia virus (Ab-MLV) encodes the v-Abl protein tyrosine kinase and induces transfor- mation of immortalized fibroblast lines and pre-B ...cells. Temperature-sensitive mutations ... See full document
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Intracellular localization and processing of pp60v-src proteins expressed by two distinct temperature-sensitive mutants of Rous sarcoma virus.
... 876 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The transforming protein of Rous sarcoma virus, pp6Ov-src, is known to be a tyrosine protein kinase, but the mechani[r] ... See full document
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Cellular localization of the transforming protein of wild-type and temperature-sensitive Fujinami sarcoma virus.
... In cells infected by mutants of FSV temperature sensitive for cellular transformation, most of the P140 is particulate at the permissive temperature, whereas most is soluble at the nonpe[r] ... See full document
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Temperature-Sensitive Mutants of Fujinami Sarcoma Virus: Tumorigenicity and Reversible Phosphorylation of the Transforming p140 Protein
... To determine whether synthesis and phosphorylation of the p140 FSV protein are necessary for the maintenance of cellular transformation, we have isolated several spontaneous and chemical[r] ... See full document
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Changes in synthesis of DNA-binding proteins during the onset of transformation in NRK cells transformed by a temperature-sensitive mutant of Rous sarcoma virus.
... If changes in the synthesis of DNA-binding proteins occur after a to 330C resulted in decreased R values, ranging shift to the permissive temperature, it might be from 0.90 to 0.98 for t[r] ... See full document
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Membrane association of the transforming protein of avian sarcoma virus UR2 and mutants temperature sensitive for cellular transformation and protein kinase activity.
... In this paper, we describe the plasma membrane localization of P68 in UR2-transformed cells by subcellular fractionation and characterize differences between its membrane association and[r] ... See full document
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Mutants of Fujinami sarcoma virus which are temperature sensitive for cellular transformation and protein kinase activity.
... A Fujinami sarcoma virus-specific protein of 130,000 daltons, p130, was synthesized in mutant-infected cells regardless of the temperature, but the immunoprecipitates of p130 from extrac[r] ... See full document
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Two independent mutations are required for temperature-sensitive cell transformation by a Rous sarcoma virus temperature-sensitive mutant.
... MAYER,- TATSUO TAKEYA,3 TADASHI YAMAMOTO,' KUMAO TOYOSHIMA,' HIDESABURO HANAFUSA,2 AND SADAAKI KAWAI1* Inistitlite of Medical Science, University of Tokyo, Minato-ki, Tokyo 108, Jaipan'1[r] ... See full document
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Distinguishable transformation-defective phenotypes among temperature-sensitive mutants of Rous sarcoma virus.
... Although the PTD mutant-infected cells, unlike cells infected with other transformation mutants, exhibit a cell-bound plasminogen activator protease at the nonpermissive temperature, thi[r] ... See full document
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Recombination between a temperature-sensitive mutant and a deletion mutant of Rous sarcoma virus.
... Transformed cell colonies induced by infection of chf-positive gs+chf+, C/E type cells with the progeny viruses were isolated from soft-agar cultures and the type of cell transformation [r] ... See full document
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Site-directed mutagenesis of the src gene of Rous sarcoma virus: construction and characterization of a deletion mutant temperature sensitive for transformation.
... Src gene product from different strains of avian sarcoma virus: kinetics and possible mechanism of heat inactivation of protein kinase activity from cells infected by transformation-defe[r] ... See full document
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Temperature-sensitive mutants of Abelson murine leukemia virus deficient in protein tyrosine kinase activity.
... 4242-4251 0022-538X/90/094242-10$02.00/0 Copyright © 1990, American Society for Microbiology Temperature-Sensitive Mutants of Abelson Murine Leukemia Virus Deficient in Protein Tyrosine [r] ... See full document
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Biochemical characterization of temperature-sensitive rabies virus mutants.
... Production of viral complementary RNA in cells infected by wild-type rabies virus at 39.60C in the presence or absence of cycloheximide.. Total unlabeled RNAs were extracted from rabies-[r] ... See full document
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DNA clone of avian Fujinami sarcoma virus with temperature-sensitive transforming function in mammalian cells.
... Our result, that the morphology of mouse 3T3 cells transformed by transfection with DNA from a temperature-sensitive strain of FSV is temperature sensitive for a transformation, provides[r] ... See full document
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