Finding quantitative trait loci for stature
Targeted Methods for Finding Quantitative Trait Loci
... phenotypic trait is the recorded time to death for each mouse upon in- fection with ...phenotypic trait distribution, violating the normality assumption in traditional approaches of QTL mapping (Figure ...
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Quantitative Trait Loci: A Meta-analysis
... 2; see large arrows in Figure 1). QTL 1–11 would be First, the candidate gene can be chosen on an a priori representative of a first QTL at 30.30 cM, QTL 16–24 belief that, due to its function, the gene is associated ...
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Quantitative Trait Loci for Murine Growth
... We examine the effects of quantitative trait loci (QTLs) on age-specific body weights and growth in the F2 intercross of the LG/J and SM/J strains of inbred mice.. Interv[r] ...
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Multiple trait analysis of genetic mapping for quantitative trait loci.
... We examined, in detail, various advantages and disadvantages of the joint analysis as compared to sepa- rate analyses for mapping QTL and also for testing a number of hyp[r] ...
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Multiple-trait multiple-interval mapping of quantitative-trait loci
... The trait correlations were chosen to be ...each trait there were two QTLs in the model, Q 1 at 35 centiMorgans (cM) and Q 2 at 85 cM, with the effects described in Table ...
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Modeling Quantitative Trait Loci and Interpretation of Models
... A quantitative genetic model relates the genotypic value of an individual to the alleles at the loci that contribute to the variation in a population in terms of additive, dominance, and epistatic ...
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A new method for Quantitative Trait Loci Detection
... Percentage of QTL truly identified (QTL found) and number of QTL found (nb of QTL found) as a function of the number of QTL, their effects, their locations and the method. threshold obta[r] ...
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Robust Methods for Analysing Quantitative Trait Loci
... trait value (the neutral marker assumption). 10. A dense map of markers can improve the accuracy and precision of QTL map- ping but there is a point where adding more tightly linked markers does not add any more ...
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Genetic complexity at expression quantitative trait loci
... was set at 0.05 for the trait Q1 that was not associated with any SNPs in the trait generating model. Table 3 reports the power analysis of the simulated DBP data, when conditioning sequentially on the MAP4 ...
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Genetic mapping of quantitative trait loci in crops
... detect quantitative trait loci (QTL) by identifying marker–trait associations, and the only fundamental difference between them is that between mapping populations, which directly determine ...
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New methods for mapping quantitative trait loci
... observed trait values are randomly shuffled over individuals (genotypes) generating a sample with the original marker information, but with trait values randomly assigned over ...
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Mapping Quantitative Trait Loci With Censored Observations
... The existing statistical methods for mapping quantitative trait loci (QTL) assume that the phenotype follows a normal distribution and is fully observed. These assumptions may not be satisfied when ...
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Multiple Interval Mapping for Quantitative Trait Loci
... the quantitative trait can region for ...a quantitative trait in the broad sense, can be shown that if epistasis is present and ignored in where V G and V p are the genetic and phenotypic ...
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Mapping Environment-Specific Quantitative Trait Loci
... Environment-specific quantitative trait loci (QTL) refer to QTL that express differently in different environments, a phenomenon called QTL-by-environment (Q 3 E) ...yield trait of ...
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Bayesian LASSO for Quantitative Trait Loci Mapping
... POSTERIOR SUMMARY AND INTERPRETATION The proposed Bayesian hierarchical models can pro- vide various graphical and tabular summaries that assess the contribution of individual loci while adjusting for effects of ...
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Mapping Quantitative Trait Loci for Expression Abundance
... regular quantitative trait to be included as an expression trait and subject to the same clustering ...expression trait links to a locus where a quantitative trait also links, ...
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A nonparametric approach for mapping quantitative trait loci.
... Parametric interval mapping allows efficient de- tection and localization of QTLs for normally distrib uted traits, while keeping the false positive rate low through the[r] ...
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Review of Quantitative Trait Loci Identified in the Chicken
... major trait categories (Table 1): “growth” for traits related to BW, body composition, and feed intake; “egg” for traits related to egg production, egg quality and skeleton; “dis- ease resistance” (DR) for traits ...
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Statistical Power of Expression Quantitative Trait Loci for Mapping of Complex Trait Loci in Natural Populations
... the trait of interest may be ...expression-level trait and disease and the power to map eQTL for that expression-level ...expression-level trait is on a disease-causative eQTL, the easier it is to ...
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Interval mapping of quantitative trait loci employing correlated trait complexes.
... Besides of increased power of the statisti- cal test and higher precision of estimation of the ge- netic parameters, the proposed approach allows for an integral evaluati[r] ...
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