[PDF] Top 20 Characterization of major recognition sequences for a herpes simplex virus type 1 origin-binding protein.
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Characterization of major recognition sequences for a herpes simplex virus type 1 origin-binding protein.
... 4096-4103 0022-538X/88/114096-08$02.00/0 Copyright C 1988, American Society for Microbiology Characterization of Major Recognition Sequences for a Herpes Simplex Virus Type 1 Origin-Bind[r] ... See full document
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Purification and characterization of UL9, the herpes simplex virus type 1 origin-binding protein.
... Two binding sites for the herpes simplex virus type 1 UL9 protein are required for efficient activity of the oriS replication origin.. Genetic analysis of temperature-sensitive mutants w[r] ... See full document
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Properties of the novel herpes simplex virus type 1 origin binding protein, OBPC.
... whose origin binding sites are occupied by OBPC and not OBP would not serve as templates but rather would be directed to the packaging ...C protein, which in- hibits further rounds of replication ... See full document
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Genome Replication and Progeny Virion Production of Herpes Simplex Virus Type 1 Mutants with Temperature-Sensitive Lesions in the Origin-Binding Protein
... 7. Brown, S. M., D. A. Ritchie, and J. H. Subak-Sharpe. 1973. Genetic studies with herpes simplex virus type 1. The isolation of temperature sensitive mutants, their arrangement into ... See full document
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ICP4, the major transcriptional regulatory protein of herpes simplex virus type 1, forms a tripartite complex with TATA-binding protein and TFIIB.
... Specifically, the simultaneous addition of ICP4, rTFIIB, and rTBP to a DNA template containing an ICP4 binding site and a TATA box resulted in a unique complex lower in electrophoretic m[r] ... See full document
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Characterization of herpes simplex virus 2 temperature-sensitive mutants whose lesions map in or near the coding sequences for the major DNA-binding protein.
... In cells infected with certain of these mutants at the nonpermissive temperature, the association of the major DNA-binding protein with the cell nucleus was defective.. In these cells, t[r] ... See full document
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Interaction with nucleic acids and stimulation of the viral DNA polymerase by the herpes simplex virus type 1 major DNA-binding protein.
... 727 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The interaction of the herpes simplex virus type 1 HSV-1 major DNA-binding protein, infected-cell polypeptide 8 ICP8[r] ... See full document
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Helicase Motif Ia Is Involved in Single-Strand DNA-Binding and Helicase Activities of the Herpes Simplex Virus Type 1 Origin-Binding Protein, UL9
... Western blot analysis. Western blot analysis was performed as previously described (4). Anti-UL9 primary antibodies recognizing the C-terminal residues 841 to 851 (R250, a kind gift from M. Challberg, National Institutes ... See full document
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Mutational analysis of sequences downstream of the TATA box of the herpes simplex virus type 1 major capsid protein (VP5/UL19) promoter.
... While it has been clear for a long time and has been reconfirmed in the accompanying report 11 that such assays of HSV promoter activity do not always accurately reflect kinetics or iden[r] ... See full document
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Structural requirements in the herpes simplex virus type 1 transactivator Vmw65 for interaction with the cellular octamer-binding protein and target TAATGARAT sequences.
... 2716 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Herpes simplex virus type 1 virion protein Vmw65 forms a complex TRF.C with TAATGARAT sequences and the cellular tr[r] ... See full document
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Use of transdominant mutants of the origin-binding protein (UL9) of herpes simplex virus type 1 to define functional domains.
... by binding origin DNA into an inactive ...ATP binding and hydrolysis, since they contain the estab- lished ATP-binding consensus sequences (32, ...ATPase binding and/or ... See full document
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Origin Binding Protein-Containing Protein-DNA Complex Formation at Herpes Simplex Virus Type 1 oriS: Role in oriS-Dependent DNA Replication
... on origin-dependent HSV DNA replication, the mutOBP and mutR(C-G) mutations were in- troduced into the wild-type oriS-containing plasmid, pOS822, and the effects of these mutations were evaluated in in ... See full document
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Mutations in the major DNA-binding protein gene of herpes simplex virus type 1 result in increased levels of viral gene expression.
... We have found that at the nonpermissive temperature, the synthesis of certain immediate early, early, and late viral polypeptides was greater in cells infected with the temperature-sensi[r] ... See full document
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Genetic analysis of temperature-sensitive mutants which define the gene for the major herpes simplex virus type 1 DNA-binding protein.
... 354-366 0022-538X/83/010354-13$02.00/0 Copyright C 1983, American Society for Microbiology Genetic Analysis of Temperature-Sensitive Mutants Which Define the Gene for the Major Herpes Si[r] ... See full document
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Structural Characterization of the UL25 DNA-Packaging Protein from Herpes Simplex Virus Type 1
... Cluster 1 is located in the apical region of the protein lo- cated on the same face as the view shown in ...cluster 1, traverses laterally across the entire molecule and abuts disordered loop ... See full document
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Expression of herpes simplex virus type 1 major DNA-binding protein, ICP8, in transformed cell lines: complementation of deletion mutants and inhibition of wild-type virus.
... In addition to cell lines which complemented ts mutants, two lines, U-27 and U-35, significantly inhibited plaque formation by wild-type virus, contained 30 and 100 copies of the ICP8 ge[r] ... See full document
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Herpes simplex virus type 1 UL14 tegument protein regulates intracellular compartmentalization of major tegument protein VP16
... Aggregates of VP16GFP, UL46, and UL14(3P) were surround by vimentin and sequestered in the cytoplasm, indicating aggresome formation. Aggresomes are formed in cells when there is a large amount of misfolded or insoluble ... See full document
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Surface lysine and tyrosine residues are required for interaction of the major herpes simplex virus type 1 DNA-binding protein with single-stranded DNA.
... 11 0022-538X/92/116273-07$02.00/0 Copyright © 1992, American Society for Microbiology Surface Lysine and Tyrosine Residues Are Required for Interaction of the Major Herpes Simplex Virus [r] ... See full document
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Characterization of a major DNA-binding domain in the herpes simplex virus type 1 DNA-binding protein (ICP8).
... ICP8, the major DNA-binding protein from herpes simplex virus type 1 HSV-1, belongs to a class of singlestranded DNA-binding proteins.. These proteins are required for DNA replication, p[r] ... See full document
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Phosphorylation of the Herpes Simplex Virus Type 1 Origin Binding Protein
... The herpes simplex virus type 1 (HSV-1) origin binding protein (OBP), the product of the UL9 gene, is one of seven HSV-encoded proteins required for viral ... See full document
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